Principal Scientist, Protein Formulation & Drug Product
Denali Therapeutics
Denali is seeking a Principal Scientist to lead formulation and drug product process development for its protein biologics portfolio in California. You will drive formulation studies, understand degradation mechanisms, and support scale-up and validation. The role requires a PhD with 10+ years in protein therapeutics formulation, hands-on analytical characterization, and strong regulatory and CMO transfer experience. Collaboration across discovery, analytics, bioprocess, and quality is essential. #J-18808-Ljbffr
$159k - $207k
...meaningful therapeutics to patients. We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a formulation and... ...process development lead for our growing portfolio of protein biologics. This individual will provide technical...PrincipalContract workLocal area- ...AbbVie in South San Francisco, CA, seeks a Principle Scientist I for the Drug Product Development group. This on-site role leads external CDMO interactions, guiding formulation and process development for biologics, and ensuring compliant, efficient outsourcing. You...Principal
$167.4k - $310.8k
...sciences are transforming drug discovery and... ...Intelligence (AI) to assist our scientists in both pRED and gRED... ...seeking a Senior or Principal Machine Learning... ...workflows.Research-to-Production Impact: Partner with researchers... ...modalities (e.g., protein sequences, chemical...PrincipalFull timeLocal areaWorldwideRelocation package- ...and neuroscience - and products and services in our... ...Job Description The Drug Product Development group... ...drug product formulations and manufacturing processes... ...exciting opportunity for a Scientist I/II to join our team... ...understanding of protein degradation pathways and...SuggestedFull timeTemporary workLocal area
- IDEAYA Biosciences in South San Francisco seeks a Senior Principal Research Scientist to lead Protein Sciences programs, supervise a small team, and solve complex protein-production challenges across multiple drug-discovery projects. You will master recombinant...Principal
- ...South San Francisco seeks a Senior Principal Research Scientist to lead Protein Sciences, supervise a small team, and solve challenging protein-production problems across multiple programs. You... ...systems, contributing to a diverse drug-discovery portfolio. You will work onsite...Principal
$129k - $151k
...an energetic, technically versatile scientist to join our Drug Product Development team and take ownership... ...and characterizing biomolecules (proteins, polysaccharide conjugates, vaccines... ...with vaccines and adjuvant-containing formulations is a plus.In addition, Vaxcyte is...Flexible hoursShift work$175k - $190k
...Principal Scientist / Associate Director, Developability & Protein Sciences About Cartography Biosciences Cartography... ...peptide mapping LC-MS), and early formulation development. Help define... ...Oversee research-stage protein production from 1 mL to 10 L scale, in house...Principal$164k - $205k
Principal Scientist, Protein Engineering South San Francisco, California, United States Xaira is an innovative... ...focused on leveraging AI to transform drug discovery and development. The company... ...therapeutic hypotheses and target product profiles, and develop integrated, AI-...PrincipalFlexible hours- AbbVie Inc. in South San Francisco, CA, seeks a Principle Scientist I to lead outsourced drug product development as the primary technical interface with CDMOs. This on-site role drives formulation and process development, ensuring alignment of strategy, timelines, risks...Principal
- ...and neuroscience - and products and services in our... ...Job Description The Drug Product Development (DPD... ...characterizing drug product formulations and manufacturing... ...opportunity for a Principle Scientist I to join our team at... ...techniques used for protein characterization and...PrincipalContract workLocal area
$201.3k - $373.8k
...computational sciences are transforming drug discovery and development.... ...(AI) to assist our scientists in both pRED and gRED to deliver... ...looking for an exceptional Principal Scientist who can architect how... ...research-stage models into production-ready components with clear interfaces...PrincipalLocal areaWorldwide- IDEAYA is seeking a Senior Principal Research Scientist to lead the Protein Sciences group at our South San Francisco headquarters. The role focuses on solving protein production challenges, mentoring scientists, and coordinating CROs for expression and characterization...Principal
- ...in South San Francisco, CA, invites a Principal Scientist in Structural Biology to lead cross-functional... ...and computational modeling to reveal protein dynamics and ligand interactions. You... ..., and translate insights into drug discovery strategies. The role emphasizes...Principal
- Genentech's Department of Protein Sciences in South San Francisco seeks a Principal Scientist in Structural Biology to drive drug discovery by integrating structural data, computational modeling, and biophysical insights. You will oversee protein construct design, expression...Principal
$167.4k - $310.8k
...computational sciences are transforming drug discovery and development. Roche’s Research... ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative... ...representation learning machine learning models for protein and antibodies in zero-shot and few-shot...Full timeLocal areaWorldwideRelocation packageShift work- ...and neuroscience - and products and services in our... ...Job Description The Drug Product Development group... ...drug product formulations and manufacturing processes... ...exciting opportunity for a Scientist I/II to join our team... ...understanding of protein degradation pathways and...Full timeTemporary workLocal area
- ...AbbVie seeks a Principal Research Scientist I to serve as the primary technical liaison between its Drug Product Development group and external Contract... ...role manages outsourced formulation and process development... ...Hands-on experience with protein characterization...PrincipalContract work
- ...Vir Biotechnology seeks a Senior Scientist I for a 12+ month temporary contract to lead drug product and device development efforts. The role combines technical laboratory work with scientific leadership for formulation development of biologics, supporting clinical-stage...Contract workTemporary work
- Genentech is seeking a talented and highly motivated Scientist to focus on formulation development within the PharmDev Department. You will engage in innovative process development, formulation, analytical/biophysical characterization, and analytical method optimization...
$177k - $235k
...industry partners, its vibrant drug-development pipeline,... ...seeking an innovative Senior Scientist / Principal Scientist to bridge the gap... ...-PhD experience in antibody/protein engineering within the biotech... ...vitro library design, protein production, and screening assaysAbility...Principal- Nurix Therapeutics is seeking a Principal Engineer, Pharmaceutical Development Engineering to own hands-on engineering turning a molecule into a manufacturable drug product. You will lead process development, scale‑up, and CDMO operations for late‑stage programs, with...Principal
$201.3k - $373.8k
...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early... ...transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and...PrincipalFull timeLocal areaWorldwideShift work$201.3k - $373.8k
...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early... ...transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and...PrincipalFull timeWork experience placementLocal areaWorldwideRelocation package$150.7k - $279.9k
...PositionThe Department of Protein Sciences at Genentech... ...-versed in protein production and purification, structure... ...environment for drug discovery and biomedical... .... We collaborate with scientists throughout the... ...therapeutics.The OpportunityAs a Principal Scientist in...PrincipalFull timeWork at officeLocal areaWorldwideRelocation package$176.2k - $277.3k
...Program Leader (DPL) to represent Nonclinical Drug Safety (NDS) on discovery research teams... ...on preclinical studies to support product development. Qualifications, skills and... ...industry experience as a non-clinical safety scientist (e.g. Toxicology, Pathology etc.) and/or...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$147.8k - $320.2k
Genentech is looking for a highly motivated Senior/Principal Machine Learning Scientist in South San Francisco. This role is pivotal in developing machine learning models for drug discovery, requiring a deep understanding of perturbation data and collaboration with diverse...Principal- IDEAYA Biosciences in South San Francisco seeks a Senior Principal Research Scientist in Computational Chemistry with a strong industry track record... ...modeling, and mentor teams to develop potent, selective drug candidates. The role requires independence, deep technical...Principal
- ...leading biotechnology company in South San Francisco is seeking a Senior or Principal Machine Learning Scientist. In this role, you will lead the development of large language models for drug discovery tasks. You will work on designing scalable systems and translating...Principal
$159k - $207k
...starting materials, intermediates, drug substances, and drug products. Lead analytical activities for assigned... ...synthesis, purification, formulation, and degradation pathways to resolve... ...teams, collaborating with discovery scientists, process chemists, formulation, quality...PrincipalLocal area
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