Senior Principal Protein Scientist — Leadership & CRO Oversight
IDEAYA Inc
IDEAYA is seeking a Senior Principal Research Scientist to lead the Protein Sciences group at our South San Francisco headquarters. The role focuses on solving protein production challenges, mentoring scientists, and coordinating CROs for expression and characterization across multiple programs. The successful candidate will have deep experience with recombinant protein production, purification strategies, and diverse expression systems, including bacterial and insect cells, and will work onsite #J-18808-Ljbffr IDEAYA Inc
$140k - $210k
...Senior Scientist/Principal Scientist, Protein Sciences: Analytical & Biophysical Characterizations Department: Technology/Protein Sciences Work Location... ...spend time at the bench while contributing strategic leadership on analytical and developability matters....PrincipalSeniorFull timeTemporary workFlexible hours- ...Xaira Therapeutics seeks a Principal Scientist to lead protein engineering efforts in AI-driven therapeutic... ...on experimental work with scientific leadership, partnering with computational designers... ...program communication and CRO management Requirements Ph.D....Principal
$141.5k - $262.9k
...Opportunity:The responsibilities of this Senior Scientist position will :1. Portfolio... ...pharmaceutical, biotechnology, or CRO environments.Senior Principal Scientist: Ph.D. with >5+ years of... ...experience demonstrating successful safety leadership and cross-functional impact within...PrincipalSeniorFull timeLocal areaRelocation package$167.4k - $310.8k
...Intelligence (AI) to assist our scientists in both pRED and gRED to... .... We are seeking a Senior or Principal Machine Learning Scientist... ...this role, you will:Technical Leadership & Strategy: Lead the design... ...molecular modalities (e.g., protein sequences, chemical graphs,...PrincipalSeniorFull timeLocal areaWorldwideRelocation package$173.1k - $321.5k
...Safety Toxicologists provide scientific leadership across drug development, from early... ...development and marketed products. This Senior Principal Scientist role is intended for an experienced... ...experience in the pharmaceutical/biotechnology/CRO industry related to toxicology....PrincipalSeniorFull timeLocal areaImmediate startRelocation package3 days per week$180k - $223k
...and highly collaborative Senior Principal Research Scientist to make significant hands‑on contributions to our Protein Sciences function while supervising... ...of scientists, CRO coordination, and cross‑functional... ...teams and research leadership. Requirements PhD with 9+...PrincipalSeniorTemporary workWork at officeLocal areaWork from home1 day per week- ...Therapeutics in the San Francisco Bay Area is seeking a Principal Scientist to lead AI-driven protein engineering for therapeutic proteins and antibodies.... ...through early discovery with a hands-on, on-site leadership role in a fast-paced startup environment. #J-18808-Ljbffr...Principal
- ...IDEAYA Biosciences seeks an experienced Senior Principal Research Scientist to lead protein production and characterization efforts for oncology drug discovery... ...and findings to project teams and research leadership Requirements PhD with 9+ years hands-on recombinant...PrincipalSenior
- ...The Role We are seeking a Senior or Principal Analytical Scientist with deep, hands‑on... ...built for high-throughput protein profiling in neurons. You... ...proportionally more manual oversight as run volume grows. Plan... ...robotic system. Scientific Leadership & External Engagement...PrincipalSeniorContract workShift work
$164k - $205k
...development of generative AI models to design protein and antibody therapeutics, enabling the creation... ...engineering with computational design. As a Principal Scientist, you will provide scientific and technical leadership from program conception through early discovery...PrincipalFlexible hours$194.1k - $305.6k
...seeking an accomplished and highly collaborative Senior Principal Scientist to provide scientific leadership across drug conjugate discovery and development programs... ..., and regulatory packages. Provide scientific oversight for LM ADME experimentation strategy and...PrincipalSeniorFull timeContract workFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$173.1k - $321.5k
...Safety Toxicologists provide scientific leadership across drug development, from early... ...development and marketed products. This Senior Principal Scientist role is intended for an experienced... ...experience in the pharmaceutical/biotechnology/CRO industry related to toxicology....PrincipalSeniorLocal areaImmediate startRelocation package3 days per week$177k - $235k
...breakthroughs. Position Description:We are seeking an innovative Senior Scientist / Principal Scientist to bridge the gap between traditional antibody... ...(for Principal Scientist) post-PhD experience in antibody/protein engineering within the biotech or biopharma...PrincipalSenior$173.1k - $321.5k
...so that we all have more time with the people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical Strategy... ...stakeholders around shared objectives.Recognized scientific leadership through publications, presentations, patents, regulatory...PrincipalSeniorFull timeLocal areaRelocation package$150k - $200k
...Job Description Principal Scientist – Histopathology & Translational Biomarkers \n \n Location... ...Scientist to provide scientific leadership across histopathology, translational biomarker... ...\n - Biotechnology, pharmaceutical, CRO, or translational research environment...PrincipalSeniorPermanent employmentFull time$168.6k - $313k
...Opportunity We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative research and development team. This is a technical leadership position within our Peptide Therapeutics department, focused on advancing...PrincipalSeniorLocal areaRelocation package- ...Consultants is seeking a Lead, Senior, or Principal Biologist with experience... ..., and the potential for leadership. Responsibilities may include... ...that meet professional and oversight agency standards.Technical... ...with SWCA’s other resource scientists, planners, on natural and cultural...PrincipalSeniorFull timeFor contractorsFor subcontractorWork at officeLocal areaRemote work
- Genentech is seeking a Senior Principal Scientist in Translational Safety to provide scientific leadership across drug development, from discovery to clinical stages. This role leads independent toxicology and safety programs for multiple development projects, integrating...PrincipalSenior
$198.9k - $369.3k
...Safety Pathologists provide scientific leadership across drug development, from early... ...development and marketed products. This Senior Principal (SE8) role is intended for an experienced... .... The Senior Principal Pathologist-Scientist is expected to operate with a high degree...PrincipalSeniorFull timeLocal areaImmediate startRelocation package3 days per week- Denali Therapeutics Inc in South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies, establish shelf life, and support comparability across development stages...Principal
- Denali is seeking a Principal Scientist to lead formulation and drug product process development for its protein biologics portfolio in California. You will drive formulation studies, understand degradation mechanisms, and support scale-up and validation. The role requires...Principal
$165.2k - $306k
...at Genentech is excited to announce an opportunity for a Senior Principal Scientist, Lab Head, to join the Synthetic Immunity division encompassing... ...skills are essential. Key Responsibilities Research Leadership: Lead and manage a high-performing team in the discovery and...PrincipalSeniorLocal areaRelocation package$167.4k - $310.8k
...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more... ...prioritization. We are seeking a highly motivated Senior Machine Learning Scientist to join the... ...learning machine learning models for protein and antibodies in zero-shot and few-shot...SeniorFull timeLocal areaWorldwideRelocation packageShift work$101.4k - $154.7k
POSITION SUMMARY:The Senior Field Application Scientist, Protein XI (FAS) will play a critical role in supporting the launch and ongoing success of a... ...documentation, and usability.Early Access Program (EAP) Leadership• Serve as field lead for the EAP in partnership with...SeniorFull timeTemporary workFlexible hours$159k - $207k
...team while providing hands‑on scientific leadership in analytical method development,... ...program teams, collaborating with discovery scientists, process chemists, formulation,... ...analytical methods and providing technical oversight of CRO/CDMO activities, including review and...PrincipalLocal area$196k - $242k
...forward. Position Summary We are seeking an accomplished Senior Principal Research Scientist in Computational Chemistry with significant... ...Experience working on challenging target classes, including protein-protein interactions and allosteric pockets. Track record...PrincipalSeniorTemporary workWork at officeLocal areaWork from home1 day per week$159k - $207k
...seeking a talented and motivated Principal Scientist to provide strategic technical leadership for late phase and commercial... ...characterization activities as well as oversight of control strategy development... ...development experience for protein therapeutics in the biotech/...PrincipalContract workLocal area- Amgen is seeking a highly skilled scientist for the Pharmacokinetics & Drug Metabolism - Bioanalytical Sciences group to advance LC-MS... ...develop and apply fit‑for‑purpose methods to quantify target proteins, evaluate target engagement and biomarker kinetics, and support...Senior
- Amgen seeks a scientist in Pharmacokinetics & Drug Metabolism - Bioanalytical Sciences (PKDM-BA) to develop and apply LC-MS-based bioanalytical assays for endogenous proteins, proteoforms, and target-drug complexes. The role spans discovery to regulatory support, requiring...Senior
- ...Senior Scientist role focused on developing and deploying automated computational pipelines for large-scale protein binder design. The position supports molecular discovery efforts by accelerating generation of design candidates and libraries across multiple therapeutic...Senior
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