Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist, Biomarker Data Sciences

$141k - $188k

Biogen

About This Role:

As a Principal Scientist in Biomarker Data Sciences within the Clinical Biomarkers group at the West Coast Hub, you will lead the charge in multi-omics analyses of extensive clinical trial datasets, with a particular focus on NGS and proteomics. This role is pivotal in generating biological insights that will directly inform clinical development strategies. You will be advancing the understanding of CD38 immune cell-driven biology, collaborating closely with clinical teams, biostatistics, medical affairs, and key medical experts. Your ability to translate complex data into impactful insights will bring immense value to our business, ensuring our developments are both innovative and effective. With a seat at the heart of our operations, you will contribute strategically to our clinical biomarker initiatives, aligning closely with our overarching business goals.

What You'll Do:

• Lead and execute integrative multi-omics analyses from large clinical cohorts.

• Translate complex NGS and proteomics data into actionable biological and clinical insights.

• Partner closely with clinical teams, medical experts, biostatistics, and medical affairs to address critical clinical trial questions.

• Contribute to biomarker strategy, exploratory endpoints, and interpretation of clinical trial results.

• Communicate findings clearly and effectively to cross-functional, clinical, and scientific stakeholders.

Who You Are:

You are a highly collaborative individual with outstanding communication skills. Your ability to clearly translate complex data into impactful insights sets you apart. You thrive in cross-functional environments, where your expertise in bioinformatics and your passion for advancing clinical research drive you. Your approach is both analytical and creative, enabling you to contribute significantly to clinical biomarker strategies. Your enthusiasm for working with diverse teams and your commitment to excellence make you an invaluable asset to our organization.

Required Skills:

• PhD in Bioinformatics, Computational Biology, Immunology, or a related field.

• 5+ years of relevant industry experience.

• Hands-on experience analyzing NGS and/or proteomics data from large clinical datasets.

• Outstanding written and verbal communication skills and a demonstrated ability to work in highly collaborative, cross-functional environments.

Preferred Skills:

• Relevant postdoctoral training.

• Background in immunology and/or autoimmune disease biology.

• Experience supporting biomarker discovery and mechanism-of-action studies in clinical trials.

Job Level: Professional

Additional Information

The base compensation range for this role is: $141,000.00-$188,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.


In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:
  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
Vacancy posted 5 hours ago
Similar jobs that could be interesting for youBased on the Principal Scientist, Biomarker Data Sciences in San Francisco, CA vacancy
  • $140k - $187k

     ...About This Role: As a Principal Scientist in Clinical Biomarkers, you will play a pivotal role in the design...  ...delivery of high-quality biomarker data. This role is crucial in aligning study...  ...or cellular biology, translational sciences, or a related discipline. • 5+... 
    Principal
    Contract work
    Temporary work
    Local area

    Biogen

    San Francisco, CA
    1 day ago
  • $182.54k - $211.14k

     ...collaborative, innovative, and science based. If you have a passion...  ...your career. Principal Scientist - Computational Biology & Translational...  ...Agentic AI), multi-modal data integration, combined with strong...  ...foundation in clinical biomarkers and translational science.... 
    Principal
    Remote work
    Flexible hours

    Amgen

    South San Francisco, CA
    4 days ago
  • $142k - $190k

     ...motivated and accomplished Principal Scientist with deep drug discovery and...  ...foundation in experimental design, data interpretation, and...  ...validate novel drug targets, biomarkers, and pathways critical to immune...  ..., and computational sciences-to advance target identification... 
    Principal
    Temporary work
    Local area
    Relocation

    Biogen

    San Francisco, CA
    4 days ago
  •  ...Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational...  ...to translate the benchtop science of preclinical discovery into compounds...  ...in full development Development of biomarker strategies through cross-functional teams... 
    Principal
    Worldwide

    Merck

    San Francisco, CA
    1 day ago
  • Client is seeking an experienced and driven scientist/engineer to lead late-stage upstream cell culture process development activities for clinical and commercial-stage large molecule programs. This individual will serve as the upstream lead for scale-up and tech transfer... 
    Principal
    Contract work

    CeDent

    San Francisco, CA
    4 days ago
  • $288k

     ...the hardest problems in medicine. Within Life Sciences AI (LSAI), we are standing up a new AI for Cell...  ...imaging, genetics, and multi-modal experimental data. We are seeking a Principal or Sr. Principal BioML Scientist to be a co-architect of how Lila's autonomous... 
    Principal
    Full time
    Work at office
    Local area
    Flexible hours
    Shift work

    Lila Sciences

    San Francisco, CA
    4 hours ago
  • $360k

     ...hardest problems in medicine. Within Life Science AI (LSAI), we are launching a new...  ..., and multi-modal experimental data that integrate deep biological expertise...  ...systems. We are seeking a Sr. Principal or Distinguished ML Scientist to be the founding senior ML Scientist... 
    Principal
    Full time
    Work at office
    Local area
    Flexible hours

    Lila Sciences

    San Francisco, CA
    2 days ago
  •  ...discovery, hit validation, dose-response studies, SAR and MOA studies) Proficiency in: Managing a team of exceptional scientists and research associates Target/indication selection Animal models of cancer (GEMM, orthotopic, xenograft models), in vivo... 
    Principal

    General Proximity

    San Francisco, CA
    3 hours ago
  • $268k - $384k

     ...Senior / Principal ML Scientist, Foundation Models for Life Sciences San Francisco, CA USA Your Impact at LILA Lila is building a platform where AI and...  ...state-of-the-art machine learning and life science data, spanning biological sequences, molecular structures... 
    Principal
    Full time
    Work at office
    Local area
    Flexible hours

    Lila Sciences

    San Francisco, CA
    1 day ago
  • $180k - $215k

     ...collaborative, detail-oriented Principal Scientist to join our Translational...  ...advance, support, and execute biomarker discovery, mechanism-of-...  ...investigations, and translational data analysis from clinical...  ...Strong foundation in biological sciences, with experience or interest... 
    Principal
    Work at office
    Flexible hours
    Shift work

    Nkarta Inc

    South San Francisco, CA
    3 hours ago
  • $163.67k - $221.44k

     ...collaborative, innovative, and science based. If you have a passion...  ...your career. Principal Scientist-PKDM, Modeling and Simulation...  ...archive contributions including data analyses, mathematical models...  ...chemistry, biology, toxicology, biomarkers and protein scientists... 
    Principal
    Flexible hours

    Amgen

    South San Francisco, CA
    3 days ago
  • $139.9k - $274.8k

     ...and Azure OpenAI. We are looking for a Principal Applied Scientist to join our team! Microsoft's...  ...Bachelor's Degree inComputer Science, Computational Linguistics, or related...  ...in Computer Science, Machine Learning, Data Science, or a related field. ~5+ years... 
    Principal
    Ongoing contract
    Work at office
    Local area
    Shift work

    Microsoft Corporation

    San Francisco, CA
    1 day ago
  • $197.3k - $313.7k

     ...duplicating efforts. Job Category Data Job Details About Salesforce...  .... Position Overview: As a Decision Scientist within the Data & Analytics organization,...  ...gains and organic trends using various data science and modeling techniques at your disposal.... 
    Principal

    Salesforce.Com Inc

    San Francisco, CA
    4 days ago
  • $180k - $260k

     ...as much on our people as it does on our science and are building a workplace that...  ...Senior Staff level for a Bioinformatics / Data Scientist to join Rezo's Computational Biology and...  ...spanning from mechanism of action to patient biomarker selection strategies. Build internal... 
    Summer work
    Local area
    Flexible hours

    Rezo Therapeutics

    San Francisco, CA
    4 days ago
  • $142.8k - $274.8k

     ...#VivaEngage About this Job As aPrincipalApplied Scientist at Viva Engage, your role is to build Agentic...  ...quality, time saved). Own end-to-end delivery of applied science solutions: problem framing data/labels modeling/prompting evaluation experimentation (A... 
    Principal
    Ongoing contract
    Work at office
    Local area

    Microsoft Corporation

    San Francisco, CA
    22 hours ago
  • $228.7k - $309.4k

     ...initiatives in robotic intelligence. As a Principal Applied Scientist, you'll spearhead the development of...  ...such as perception, manipulation, science understanding, sim2real transfer, multi...  ...perception using images, videos, and sensor data, to sophisticated manipulation... 
    Principal
    Full time
    Temporary work
    Seasonal work
    Local area
    Flexible hours

    Amazon

    San Francisco, CA
    4 hours ago
  •  ...Senior / Staff / Principal Machine Learning Engineer Location: Onsite...  ...deep learning models. Data Handling: Preprocessing,...  ...Collaboration: Working with data scientists, software engineers, and...  ..., or scikit-learn. Data Science Fundamentals: Solid understanding... 
    Principal

    Lead Allies Inc.

    San Francisco, CA
    10 days ago
  • $204.5k - $267k

     ...Principal Data Scientist, Medical Imaging New York, NY; Boston, MA About Formation Bio Formation...  ...in clinical trials, incl. AI-based biomarkers and surrogate endpoints...  ...Qualifications ~ PhD in Computer Science, Biomedical Engineering, Medical Physics... 
    Principal
    Work at office
    Local area
    Relocation
    3 days per week

    Formation Bio (Formerly TrailSpark)

    San Francisco, CA
    18 hours ago
  •  ...Job Description Senior Data Engineer Principal, Lead on site Client is building a global consumer neobank, merging banking, payments, and crypto into a single product. Our initial focus is emerging markets, where traditional banking and local currencies fail... 
    Principal
    Local area
    Flexible hours

    Simple Solutions

    San Francisco, CA
    1 day ago
  • $201.7k - $267.3k

     ...Principal Data Scientist : Product to Market (P2M) Optimization Full time Two Folsom, San Francisco, CA, US 94105 Gap Inc. is seeking a...  ...driving enterprise-scale impact through optimization and data science initiatives spanning pricing, inventory, and assortment... 
    Principal
    Minimum wage
    Full time

    Gap Inc.

    San Francisco, CA
    22 hours ago
  •  ...Job Details: Duration: 12 months contract Summary: ~ Support biomarker discovery using human samples (whole blood, PBMCs), focusing on generating high-quality, reproducible data in a highly collaborative environment. Responsibilities: Execute and analyze... 
    Contract work

    US Tech Solutions

    South San Francisco, CA
    23 hours ago
  •  ...high-performing, fast-paced Growth/PLG leadership team that drives data-driven strategy across the organization. Program management...  ...functional teams, Exec reporting associated with OKR targets, and a data science team with an ambitious strategic roadmap. Duties... 
    Principal
    Shift work

    Mindlance

    San Francisco, CA
    3 days ago
  •  ...Principal AI Agent Engineer Liberate builds AI agents to automate manual tasks for the $2.7T insurance industry. We started with...  ...repeat incidents and toil Partner closely with Platform, Data Science, and Product to shape agent strategy Design reusable frameworks... 
    Principal
    Work at office
    2 days per week

    Venturefizz Product Management Community

    San Francisco, CA
    1 day ago
  • $157k - $281.93k

     ...Architecture, Engineering, and Construction), we are seeking a Senior Principal Content Strategist to lead system-level content strategy for...  ...Partner closely with Product, Design, Engineering, Research, Data Science, and Design Systems to shape agent behaviors and content... 
    Principal
    Remote work

    Autodesk

    San Francisco, CA
    4 days ago
  •  ...companies to build the foundational data layer that will power the...  ...our data strategy. We need a scientist who can lead—not just manage—...  .... The Role As our Principal Scientific Data Scientist,...  ...Pharmacology, or a closely related life sciences field. Domain Expertise:... 
    Principal
    For contractors

    Oakwell Hampton Group

    San Francisco, CA
    3 days ago
  •  ...and Construction), we are seeking a Senior Principal Content Strategist to lead content strategy for Forma Construction and Data. This team is responsible for the construction...  ..., Design, Engineering, Research, Data Science, and other cross-functional roles to ensure... 
    Principal
    For contractors
    Remote work

    Autodesk

    San Francisco, CA
    8 days ago
  • $132k - $264k

     ...Principal Data Scientist New York, NY: $132,000 - $264,000/yr San Francisco, CA: $143,000 - $286,000/yr Regular/ Permanent Salaried Position...  ...and business questions into well-scoped ML and data science work. Build, evaluate, and iterate on advanced deep learning... 
    Principal
    Permanent employment

    disABLEDperson Inc

    San Francisco, CA
    3 hours ago
  • $119.8k - $234.7k

     ...inCoreAI,you'llsit at the intersection ofproduct, engineering, and data, drivingexperimentation, learning velocity, andreal...  ...quality and confidence ~ Partner closely withProduct, Data Science, Design, and Researchto turn hypotheses into shipped learnings... 
    Principal
    Ongoing contract
    Local area

    Microsoft Corporation

    San Francisco, CA
    3 days ago
  •  ...Principal Product Manager, Data Procore has the richest construction dataset in the industry. We're looking for a Principal Product Manager, Data...  ...cross-functional collaboration with Engineering, Data Science, Data Engineering, and Go-to-Market teams through all phases... 
    Principal
    For contractors
    Work at office
    Immediate start

    Procore Technologies

    San Francisco, CA
    22 hours ago
  • $175k - $205k

     ...seeking a highly motivated and experienced Principal Scientist to join our Functional Genomics team...  ...technologies, and drive high-quality data generation and experimental innovation...  ...collaborating closely with computational and data science teams Demonstrated ability to... 
    Principal
    Flexible hours

    Xaira Therapeutics

    South San Francisco, CA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist, Biomarker Data Sciences. Be the first to apply!