Pharmacokinetics/PC(PK/PD) Principal Scientist

An established global biopharmaceutical organisation is seeking a talented PK/PD Scientist to join its Clinical Pharmacology and Modelling & Simulation function. This is an exciting opportunity to contribute to the development of innovative therapies within a science-led, collaborative environment. As a PK/PD Scientist, you will apply quantitative pharmacology principles to support drug development programmes across multiple therapeutic areas. Working alongside cross-functional teams, you will help drive critical development decisions through pharmacokinetic, pharmacodynamic, and modelling & simulation approaches. Key responsibilities Conduct pharmacokinetic (PK), pharmacodynamic (PD), and PK/PD analyses to support clinical development programmes. Develop and implement modelling and simulation strategies to inform dose selection, study design, and programme strategy. Perform population PK and exposure-response analyses using industry‑standard tools. Interpret and communicate complex scientific data to multidisciplinary project teams. Collaborate with Clinical Pharmacology, Biostatistics, Translational Medicine, Regulatory Affairs, and Clinical Development colleagues. Contribute to regulatory submissions, technical reports, publications, and scientific presentations. Support the advancement of quantitative clinical pharmacology capabilities across the organisation. What you'll need PhD, PharmD, MSc, or equivalent qualification in Pharmacology, Pharmacometrics, Pharmaceutical Sciences, Statistics, Mathematics, Engineering, or a related discipline. Experience in PK/PD modelling and simulation within a pharmaceutical, biotechnology, or CRO environment. Proficiency with relevant software such as NONMEM, Monolix, Phoenix WinNonlin, R, or equivalent platforms. Strong understanding of drug development and clinical pharmacology principles. Excellent analytical, communication, and problem‑solving skills. Ability to work effectively within a collaborative, matrixed environment. #J-18808-Ljbffr Barrington James Limited