Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist, AI-Driven Pipeline Strategy

Flagship Pioneering, Inc.

Flagship Pioneering, Inc. seeks a Principal Scientist for Pioneering Intelligence to lead AI-powered clinical and commercial pipeline strategy. The role fuses scientific leadership with agentic AI to codify and scale decision-making across the portfolio. The successful candidate brings deep translational medicine experience, strong expertise in pipeline strategy, and proven use of frontier LLMs to advance therapeutic development in collaboration with Flagship ecosystem partners. #J-18808-Ljbffr Flagship Pioneering, Inc.

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Principal Scientist, AI-Driven Pipeline Strategy in Cambridge, MA vacancy
  • $166.77k - $202.09k

     ...more: careers.bms.com/working-with-us. Principal Scientist, AI-Driven Oncology Target Discovery The...  ...data-driven decisions across a rich pipeline of next-generation medicines. In doing...  ...nomination, validation, and portfolio strategy. In partnership with cross-functional... 
    Principal
    Pipeline
    Hourly pay
    Full time
    Temporary work
    Part time
    For contractors
    Summer work
    Live in
    Work at office
    Local area
    Remote work
    Flexible hours
    Shift work

    Bristol Myers Squibb EU Policy

    Cambridge, MA
    1 day ago
  • $144.65k - $216.97k

     ...and visionary Associate Principal Scientist to lead Biologics AI innovation at AstraZeneca...  ...defining and executing the AI strategy that integrates state‑of‑...  ...measurable impact on pipeline goals.Program ownership:...  ...shaping the future of AI-driven biologics discovery and engineering... 
    Principal
    Pipeline
    Full time
    Temporary work

    AstraZeneca

    Cambridge, MA
    3 days ago
  • Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects...  .... You will define pragmatic AI strategies and oversee cross-functional...  ...protein design and omics pipelines with agentic workflows. The role... 
    Principal
    Pipeline

    Pioneering Intelligence

    Cambridge, MA
    22 hours ago
  •  ...Intelligence, part of Flagship Pioneering, seeks a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational programs accelerating...  ...platform companies. You will define pragmatic AI strategies, oversee method and platform development across omics... 
    Principal

    Socket

    Cambridge, MA
    3 days ago
  • $115k - $215k

     ...building an industry-leading pipeline of oral small molecule degraders...  ...shared, our decisions data-driven and our camaraderie genuine....  ...Leadership and Experimental Strategy:Partner with cross-functional...  ...organized, solutions-oriented scientist with the ability to manage multiple... 
    Principal
    Pipeline

    Kymera Therapeutics

    Watertown, MA
    3 days ago
  • $148.5k - $214.5k

    Job title: Senior Principal Scientist/Principal Scientist, Real-...  ...direct impact on R&D strategy You will operate in an...  ...immunoscience meets bold, AI-powered research. In R...  ...SanofiWe’re an R&D-driven, AI-powered biopharma...  ...system - and innovative pipeline - enables us to invent... 
    Principal
    Pipeline
    Full time

    Sanofi

    Cambridge, MA
    2 days ago
  • $142.5k - $256.5k

     ...setting experimental strategy and partnering...  ...is intended for a scientist ready to own and evolve...  ...integrates with AI- and structure-...  ...across Moderna’s pipeline.The candidate in this...  ...-based, or AI-driven protein design workflows...  ...consistent with a Principal Scientist role.... 
    Principal
    Pipeline
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    4 days ago
  • $142.5k - $256.5k

     ...and highly motivated Principal Scientist to build, optimize, and...  ...computational biology, AI/ML, functional assay...  ...-end TCR optimization pipeline that connects library...  ...recommend optimization strategies.Support current and future...  ...a fast-paced, program-driven environment.A desire... 
    Principal
    Pipeline
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    4 days ago
  • $142.5k - $256.5k

     ...accomplished and highly motivated Principal Scientist to join the Antibody...  ...enable new treatment strategies across Moderna's therapeutic pipeline.This Principal...  ...sequence analysis, and data-driven lead selection.Design,...  ..., structural modeling, AI/ML-enabled discovery... 
    Principal
    Pipeline
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    22 hours ago
  •  ...accomplished and experienced Scientist to lead the Immune Cell Depletion...  ...Responsible for refining the strategy and biology focus within this...  ...into the drug discovery pipeline Proven experience in managing...  ...critical evaluation and data‑driven decision making. Provide expert... 
    Principal
    Pipeline
    Work experience placement

    BioSpace

    Cambridge, MA
    22 hours ago
  • $187.63k - $207.38k

     ...highly motivated and innovative Principal Scientist in Immunology to lead...  ...mechanism-based therapeutic strategies, advancing degrader programs...  ...to a high-impact pipeline addressing significant unmet...  ...chemistry data to enable data-driven decisions and portfolio prioritization... 
    Principal
    Pipeline

    C4 Therapeutics Inc

    Watertown, MA
    1 day ago
  •  ...client is looking for a Principal Quality Assurance...  ...frameworks, and introducing AI-assisted quality engineering...  ...and compliance-driven testing environments What...  ...Tech Breakdown 35% QA strategy, team leadership, and offshore...  ...CI/CD integration, and pipeline support Daily... 
    Principal
    Pipeline
    Full time

    Motion Recruitment

    Boston, MA
    22 hours ago
  • $192k - $265k

     ...oriented machine learning scientist to join our Model-Driven Design team. This role will...  ...the ML methods, data strategies, and closed-loop systems that...  ...biology company pioneering the AI revolution in drug design...  ...are advancing a growing pipeline of clinical and... 
    Pipeline
    Work at office
    Shift work

    Generate Biomedicines

    Somerville, MA
    4 days ago
  • $117k - $201.25k

     ...at Position Summary The Principal Scientific Data Scientist will lead the design,...  ...products and integration strategies supporting AI-enabled drug discovery and...  ...models to support data-driven translational safety decision...  ...deliver scalable data pipelines and data products.... 
    Principal
    Pipeline
    Local area
    Immediate start

    Johnson & Johnson Innovative Medicine

    Cambridge, MA
    2 days ago
  • $71.25k - $187k

     ...work worth doing. If you’re driven by purpose and ready to...  ...seeking an exceptional Senior Principal Scientist to join our growing team. In...  ...refine analytical testing strategies for circular RNA and lipid...  ...studies for lead candidates and pipeline programs. Troubleshoot... 
    Principal
    Pipeline
    Full time
    H1b
    Visa sponsorship
    Work visa
    Flexible hours

    BioSpace

    Watertown, MA
    4 days ago
  • Sanofi in Cambridge, MA is seeking a Senior Scientist in Systems Biology to decode disease...  ...mechanisms at cellular resolution and develop AI-powered workflows that accelerate...  ...multiomic data, building agentic analysis pipelines, and collaborating across biology, data science... 
    Pipeline

    BioSpace

    Cambridge, MA
    22 hours ago
  •  ...command of data engineering, AI/ML systems, and...  ...solutions encompassing data pipelines, model training and...  ...family.WHAT YOU'LL DOAs a Principal AI Solution Architect...  ...problems, or advising on strategy and ROI, you will flex...  ...long-term technology-driven success.By combining your... 
    Principal
    Pipeline
    Apprenticeship
    Immediate start
    Easy work
    Flexible hours

    McKinsey & Company

    Boston, MA
    4 days ago
  • $220k - $290k

     ...RoleCloudZero is hiring Staff and Principal Software Engineers...  ...CloudZero's push into AI cost intelligence. You'...  ...want to work on the pipeline that processed 14...  ...rebuilt around a new AI-driven detection engine. The team...  ...you've worked around. Strategy-deck AI doesn't qualify... 
    Principal
    Pipeline
    Immediate start

    CloudZero

    Boston, MA
    3 days ago
  • $182k - $242.6k

     ...Secure. Role OverviewAs Principal Data Scientist, GTM Data Science,...  .... You will shape the strategy and production systems...  ...solutions that have driven measurable business outcomes...  ...data and feature pipelines for production ML...  ...Experience applying modern AI/ML techniques,... 
    Principal
    Pipeline
    Work at office

    SimpliSafe

    Boston, MA
    22 hours ago
  • $200k - $270k

     ...mindset and modern methods, fusing strategy, consulting and customer...  ...Experience, Engineering, and Data & AI to tackle the biggest...  ...leveraging human ingenuity and AI-driven tools to drive innovation.Our...  ...scalable offerings that drive joint pipeline, revenue growth, and market... 
    Principal
    Pipeline
    Worldwide
    Flexible hours

    Publicis Media

    Boston, MA
    22 hours ago
  • Principal or Senior Principal, Anthropic AI Solutions (East Region)AI Systems & Platforms |...  ...on the sales side of the pipeline — not as an account executive...  ...usage, and integration strategies to ensure scalable,...  ...a consulting or partner-driven model. * Working knowledge... 
    Principal
    Pipeline
    Temporary work
    Work at office
    Local area

    Slalom

    Boston, MA
    2 days ago
  • $199.8k - $270.3k

     ...will define and execute the technical strategy to modernize and future-proof...  ...including SIEM/SOAR, security data pipelines, automation frameworks, and detection...  ...and response, leveraging automation, AI-enabled workflows, and data-driven decision making.Serve as a senior... 
    Principal
    Pipeline
    Full time
    Temporary work
    Local area
    Flexible hours

    Alnylam Pharmaceuticals

    Cambridge, MA
    1 day ago
  •  ...our Boston office).The Principal Full Stack Software Engineer...  ...enterprise technology strategy.- Design clean,...  ...for low‑latency, event‑driven, and API‑first systems...  ...and responsible use of AI across the SDLC to improve...  ...Snowflake and ingestion pipelines.- Practical experience... 
    Principal
    Pipeline
    Work at office
    Local area
    2 days per week
    3 days per week

    Liberty Mutual

    Boston, MA
    4 days ago
  • $126k - $234k

     ...Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal...  ...areas with a robust and diverse pipeline of innovative therapies. We...  ...that shape program strategies. As part of a truly translational...  ...modeling workflows (e.g., agentic AI).• Proactively seek... 
    Principal
    Pipeline
    Full time

    Novartis

    Cambridge, MA
    1 day ago
  • $169.1k - $314k

     ...Data Science innovation strategy within Product...  ...The Opportunity:The IA Principal Data Scientistplays a pivotal...  ...building and deploying AI/ML-powered digital solutions...  ...scalable, reproducible pipelines for data processing,...  ...approaches to construct data-driven priors for drug... 
    Principal
    Pipeline
    Full time
    Temporary work
    Local area

    Genentech

    Boston, MA
    2 days ago
  • $122.25k - $176.58k

    Job title: Principal ScientistLocation: Waltham...  ...role of Senior Scientist. The Genomic Medicine...  ...genomic medicine pipeline. This position is...  ...influencing process strategy, and serving as a...  ...immunoscience meets bold, AI-powered research....  ...:We’re an R&D-driven, AI-powered... 
    Principal
    Pipeline
    Full time

    Sanofi

    Waltham, MA
    2 days ago
  • $244k - $366k

     ...for autonomous, agent-driven experiences. Klaviyo's...  ...by a growing number of AI agents acting on...  ...Expectations align to Lead/Principal IC behaviors: establishing...  ...authoring and testing pipelines to catalog/search and...  ...isolation/replication strategies, privacy‑by‑design,... 
    Principal
    Pipeline

    Klaviyo

    Boston, MA
    22 hours ago
  • $143k - $214.5k

     ...an innovative and strategic Principal Scientist, Molecular Cloning Technologies...  ...define and drive cloning strategies that accelerate discovery, platform...  ...supporting company pipeline activities. Conceive, develop...  ...may also be reviewed using AI-assisted screening tools. We... 
    Principal
    Pipeline

    Seres Therapeutics

    Cambridge, MA
    4 days ago
  • $122.25k - $176.58k

    Job Title: Principal Scientist, Systems and Disease BiologyLocation: Cambridge...  ...resolution and pioneer AI-powered workflows that accelerate...  ....About Sanofi:We’re an R&D-driven, AI-powered biopharma...  ...immune system - and innovative pipeline - enables us to invent medicines... 
    Principal
    Pipeline
    Full time

    Sanofi

    Cambridge, MA
    3 days ago
  • $200k - $275k

     ...to technically anchor our new AI Data Engine team. This pivotal...  ...role will drive the technical strategy, architecture, and execution of...  ...the development cycle for new pipelines, ML models and get us...  ...and accessible reality. We’re driven by something more.Our journey... 
    Principal
    Pipeline
    Work at office
    Remote work

    Motional

    Boston, MA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist, AI-Driven Pipeline Strategy. Be the first to apply!