Electron Microscope Scientist

Job Family: Scientist Travel Required: None Clearance Required: Ability to Obtain Public Trust Job Title Electron Microscope Scientist What You Will Do Provide scientific, technical, and operational oversight of the cryo-EM facility. Support structural biology research through high‑quality cryo‑EM data acquisition and analysis. Manage facility operations, including instrument performance, user access, and workflow optimization. Oversee operation, maintenance, and troubleshooting of cryo‑EM instrumentation. Perform cryo‑EM sample preparation, data collection, and computational analysis. Train and support users, including students, postdocs, and senior scientists. Collaborate with NIH investigators and provide guidance on experimental design. Develop and implement standardized workflows, SOPs, and best practices. Monitor project timelines, instrument usage, and overall facility performance. What You Will Need Ph.D. in Biology or a closely related field. A minimum of THREE (3) years of experience in cryo‑electron microscopy, structural biology, or related research. Demonstrated expertise in cryo‑EM workflows, instrumentation, and facility operations. Experience with cryo‑EM data collection, processing, and analysis. Ability to maintain, calibrate, and troubleshoot advanced microscopy instrumentation. Strong organizational, project management, and multitasking skills. Ability to support and train a diverse scientific user base. Strong collaboration, communication, and leadership skills. Proficiency with Microsoft Office Suite and scientific data tools. Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred. Nice To Have Background supporting shared scientific core facilities or user‑based research environments. Familiarity with high‑throughput cryo‑EM data collection and automation tools. Exposure to negative‑stain EM workflows and complementary imaging techniques. Ability to optimize workflows for improved throughput, reproducibility, and data quality. Salary The annual salary range for this position is $74,000.00–$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs. Benefits Medical, Rx, Dental & Vision Insurance Personal and Family Sick Time & Company Paid Holidays Parental Leave 401(k) Retirement Plan Group Term Life and Travel Assistance Voluntary Life and AD&D Insurance Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts Transit and Parking Commuter Benefits Short-Term & Long-Term Disability Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities Employee Referral Program Corporate Sponsored Events & Community Outreach Care.com annual membership Employee Assistance Program Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.) Position may be eligible for a discretionary variable incentive bonus Equal Opportunity Employer Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco. #J-18808-Ljbffr US132 Guidehouse Digital, LLC