Scientist II, Clinical Pharmacology & Pharmacometrics

Immunome seeks a Scientist II in Clinical Pharmacology and Pharmacometrics to develop quantitative pharmacology strategy for oncology assets across preclinical and clinical stages. The role involves applying PK/PD modeling and simulation to inform dose selection and development decisions for targeted cancer therapies.

Responsibilities

• Develop clinical pharmacology and pharmacometrics strategy for early-stage and late-stage assets
• Apply modeling and simulation approaches to characterize drug absorption, disposition, and effect dynamics
• Collaborate with preclinical and clinical CROs to conduct and monitor pharmacology studies
• Maintain study records and ensure timely study completion aligned with program timelines

Requirements

• Extensive experience in oncology quantitative pharmacology and pharmacometrics
• Clinical pharmacology strategy development in oncology drug programs
• Proficiency with PK/PD, PBPK, and pharmacometric modeling and simulation
• Experience managing clinical pharmacology studies with CROs
• Knowledge of dose selection and go/no-go decision frameworks
• Strong communication and cross-functional collaboration skills