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Senior Director, Clinical Operations

$262.06k - $306.73k

Madrigal Pharmaceuticals

Madrigal Pharmaceuticals seeks a Senior Director of Clinical Operations to lead strategic planning and execution of global Phase I-IV clinical trials. The role involves overseeing complex programs from initiation through closeout, managing regulatory compliance, directing vendor partnerships, and building high-performing operational teams within a growing biopharmaceutical company.

Responsibilities

  • Provide strategic and operational leadership across Phase I-IV clinical development programs
  • Oversee study execution from start-up through closeout, ensuring compliance with timelines, quality, and budgets
  • Lead CRO selection, contracting, and performance monitoring through governance and key metrics
  • Manage site identification, feasibility, activation, enrollment, and retention strategies globally
  • Direct line management, coaching, and career development for clinical operations staff

Requirements

  • Extensive experience leading global clinical development programs across multiple phases
  • Demonstrated success managing complex cross-functional clinical operations initiatives
  • Strong knowledge of ICH-GCP, FDA, EMA, and regional regulatory requirements
  • Proven ability to develop and mentor high-performing clinical operations teams
  • Experience with CRO selection, contracting, and performance oversight
  • Track record of operational planning, budgeting, and risk management in clinical trials
Vacancy posted 21 days ago
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