Principal Translational Modeling Scientist for Decision
Flagship Pioneering
Flagship Pioneering's Pioneering Intelligence team in Cambridge, MA seeks a Principal Scientist to lead translational modeling and decision science. You will build mechanistic models to reduce uncertainty in drug development decisions and provide quantitative insights across programs. You will shape product requirements for AI-enabled translational tools, define context of use, and communicate results to stakeholders with defensible assumptions and transparent uncertainty. #J-18808-Ljbffr Flagship Pioneering
$146k - $236k
...portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms... ...Intelligence (PI) is building AI systems that accelerate translational decision making. This forward-deployed role bridges the gap from capability...Principal- ...Pioneering Intelligence is building AI systems that accelerate translational decision making across Flagship’s portfolio. This forward-deployed... ...uncertainty behind drug development through mechanistic modeling, quantitative analysis, and transparent uncertainty. #J-1...Principal
$138.6k - $257.4k
...motivated and experienced scientist to lead a small group... ...team within the Translational Profiling group in Discovery... ...Job Title: Senior Principal Scientist/Associate DirectorPosition... ...and tissue-based models, with hands on... ...insight generation and decision-making.Target and drug...PrincipalFull time- ...We are seeking a Senior Principal Scientist to join the US Neuromuscular... ...Cambridge, MA and help drive translational biology drug discovery efforts... ...of in vitro and in vivo models as well as cellular and biochemical... ...employer. All employment decisions will be made without regard...PrincipalLocal area
$173.2k - $272.6k
...accomplished and highly motivated Principal Scientist to provide strategic and... ..., and communication of translational and clinical biomarker strategies... ...candidate will develop decision-centric biomarker... ...Dedication to Patient Care, Disease Models, Disease Research, Imaging...PrincipalFull timeFor contractorsLocal areaFlexible hours$93.8k - $174.2k
...Research to advance the next generation of translational preclinical models for drug discovery. In this highly... ...is well suited to a collaborative scientist who enjoys troubleshooting, managing... ...and enable data-driven, real-time decisions on automated platforms.Establish,...Full timeRelocation package$114.1k - $211.9k
...motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the... ...plans are aligned with key program decisions and support target engagement, pharmacodynamic... ...biomarker plans encompassing assays, models, samples, analyses, timelines, and...PrincipalFull timeLocal areaFlexible hours$117k - $195.13k
...Development Job Sub Function: Translational Discovery & Development... ...for the best talent for a Principal Scientist, Translational Science... ...human disease biology into decision‑linked evidence plans that... ...scientists and study leads, model rigorous and inclusive scientific...PrincipalContract workImmediate start$138.6k - $257.4k
...Biomarkers group within Oncology Translational Research at Novartis... ...seeking an accomplished Imaging Scientist to join the Image Analysis... ..., optimize, and apply AI/ML models and reproducible workflows for... ..., Data, Data Analysis, Decision Making, Design Of Experiments...PrincipalFull time- Principal Scientist, Translational Computational Biology At Bristol Myers Squibb, our employees often ask,... ...science to empower key data-driven decisions across a rich pipeline of next-generation... ...and emerging biological foundation models. Given strategic direction, you will...Principal
- ...UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Principal
- ...BMS is seeking a Principal Scientist in Translational Informatics and Predictive Sciences to apply computational, bioinformatics, and ML approaches... ...tumor oncology. You will analyze data, build predictive models, and collaborate with biomarker and clinical teams to inform...Principal
$255.8k - $402.7k
...have an exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development in the... ...research, biostatistics, drug metabolism, modeling and simulation, regulatory affairs, and...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours- Sanofi in Cambridge, MA, seeks a Principal Scientist to lead Quantitative Systems Pharmacology modeling across programs. You will develop multiscale disease models... ...will collaborate with biology, chemistry, and translational teams, apply machine learning and differential...Principal
$160k - $235k
Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Boston, MA Salary Band: $160,000-$235,000 Location: Downtown... ..., and communicate results to project teams to aid in decision making as we advance molecules into and through...Principal$156.9k - $247k
...for patients across the globe.We have an exciting opportunity for a new Associate Principal Scientist to join our Oncology health economic modeling team in the Health Economic and Decision Sciences group. The preferred location for this role is West Point, PA; although...PrincipalFull timeFor contractorsWork experience placementWork at officeLocal areaFlexible hours- Senior/Principal Scientist, MPN Biology, Translational Sciences Job summary: PharmaEssentia Innovation Research Center... ...pathways, in vivo MPN mouse models and biomarker discovery to guide proof... ...scientific insights to inform decision-making and optimize study outcomes...PrincipalContract work
- Role Principal Scientist in Translational Informatics and Predictive Sciences at BMS, focusing on applying computational, bioinformatics, and machine... ...molecular data (e.g., genomics, proteomics), develop predictive models, generate mechanistic insights, and partner with...Principal
- Principal Scientist, Translational Computational Biology within BMS's Oncology Translational IPS team, focusing on embedding computational expertise... ...validation, IND-enabling studies, and early clinical decisions develop and deploy AI-enabled methods for evidence integration...Principal
$260.3k - $409.7k
...Disease and related conditions. The Principal Scientist (Clinical Director) must have a strong... ...background in basic and/or clinical translational research and a desire to work collaboratively... ..., biostatistics, drug metabolism, modeling and simulation, regulatory affairs,...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours$215k - $245k
Principal Scientist, Translational Data Science Cambridge Parabilis Medicines is a clinical-stage biopharmaceutical company dedicated to creating extraordinary... ...critical questions and analyses needed to drive Project decisions, and integrate internal and external data to establish...PrincipalShift work- ...Clinical Development Job Sub Function: Translational Discovery & Development Biomarkers... ...searching for the best talent for a Principal Scientist, Translational Science Program Lead -... ...mechanism and human disease biology into decision-linked evidence plans that guide...Principal
- ...Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA seeks a Senior Principal Scientist / Associate Director to lead a matrix team focused on imaging, spatial biology, and translational profiling. You will drive assay development, experimental design, and...Principal
$148.5k - $214.5k
Job title: Senior Principal Scientist Type 2 ImmunologyLocation:Cambridge,... ...opportunity to join Sanofi's Translational Biology team as a Senior... ...strategies to support clinical decision making and asset life cycle... ...lung, gut), mouse disease models, and or organoid...PrincipalFull time$160k - $224k
...is seeking an accomplished Principal Scientist to lead Target Binding efforts... ..., and scientific decision-making.• Partner with protein... ...with scripting, quantitative modeling, data science, or machine-learning... ...single operating model, we translate this approach into clinical...PrincipalShift work$168k - $252k
...seeking an accomplished Senior Principal Scientist with proven record of... ...scientific workflows, improve decision-making, and increase... ..., including large language models, agentic systems, retrieval... ...applicationsDemonstrated success translating scientific opportunities into...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week$168k - $252k
...make-test-analyze (DMTA) cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design,... ...interpretation, hypothesis generation, and decision-making. Although the primary... ...guardrails governing model usage, data access, computational...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week$119.7k - $222.3k
...to work seamlessly in the translational and/or clinical space, offering... ...Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations... ...planning, analyses and decision quality.Represent the PK... ...strategy, to be considered for Principal Scientist II. 4+ years of experience...PrincipalFull time$142.5k - $256.5k
...accomplished and highly motivated Principal Scientist to join the Antibody... ...strategies that guide program decisions.Monitor emerging antibody... ...technologies and translate relevant advances into ideas... ...bioinformatics, structural modeling, AI/ML-enabled discovery tools...PrincipalPermanent employmentFull timeWork from home$121.28k - $202.13k
...Our approach to R&DPrincipal Scientist (m/f/d) Genomic Technologies... ...team, within GSK R&D Translational Sciences. In the Genomic Technologies... ...portfolio and pipeline decisions.The successful candidate will... ...phenotypic layers.Predictive modelling of presence, direction and magnitude...PrincipalFull timeWork at officeLocal area
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