Senior & Principal Scientist Translational AI for Drugs
Pioneering Intelligence
Pioneering Intelligence is building AI systems that accelerate translational decision making across Flagship’s portfolio. This forward-deployed role bridges capability to impact by applying PI technologies to translational challenges and business decisions.
The successful candidate will reduce scientific uncertainty behind drug development through mechanistic modeling, quantitative analysis, and transparent uncertainty.
#J-18808-Ljbffr$168k - $252k
...accelerate the application of AI and agentic systems across drug discovery. Working at the... ...-analyze (DMTA) cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design... ..., data scientists, and senior leaders across a matrixed organization...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week- ...UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...PrincipalSenior
- ...We are seeking a Senior Principal Scientist to join the US Neuromuscular group based in Cambridge, MA and help drive translational biology drug discovery efforts with an emphasis on muscle biology . This is an opportunity for a scientific leader to advance portfolio projects...PrincipalSeniorLocal area
$138.6k - $257.4k
...motivated and experienced scientist to lead a small group... ...team within the Translational Profiling group in Discovery... ..., the group supports drug discovery projects... ...DescriptionInternal Job Title: Senior Principal Scientist/Associate... ..., including AI-enabled approaches for...PrincipalSeniorFull time$168k - $252k
...DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing,... ...computational methods and agentic AI systems for drug discovery. In this role, you will... ...applicationsDemonstrated success translating scientific opportunities into...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week$146k - $236k
...ventures, harnessing recent advances in AI, machine learning, and data to accelerate... ...) is building AI systems that accelerate translational decision making. This forward-deployed role... ...scientific uncertainty behind Flagship’s drug development and investment decisions...PrincipalSenior$119.7k - $222.3k
...artificial intelligence (AI) enabled strategies to... ...seamlessly in the translational and/or clinical space,... ...therapeutic proteins, antibody drug-conjugates,... ...to be considered for Principal Scientist II. 4+ years of experience... ...to be considered for Senior Principal Scientist.Extensive...PrincipalSeniorFull time$168k - $252k
...Vertex Pharmaceuticals seeks a senior scientific leader to advance... ...agentic systems in small-molecule drug discovery. This role bridges... ..., and engineering to develop AI-enabled workflows that enhance... ...teams to develop and deploy AI co-scientists supporting design, analysis,...PrincipalSenior$138.6k - $257.4k
...Biomarkers group within Oncology Translational Research at Novartis... ...seeking an accomplished Imaging Scientist to join the Image Analysis team... ...computational image analysis, AI/ML, and tissue-based oncology... ...supporting oncology drug discovery or early clinical development...PrincipalSenior- ...Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA seeks a Senior Principal Scientist / Associate Director to lead a matrix team focused on imaging, spatial biology, and translational profiling. You will drive assay development, experimental design, and...PrincipalSenior
- ...Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia Innovation Research Center (PIRC) is seeking a highly motivated and experienced... ..., including cytokines, antibodies, antibody-drug-conjugates, cell-based therapies and small molecules...PrincipalSeniorContract work
- Biogen is seeking a Sr. Principal Scientist, Oral Drug Product Development to lead formulation design, process development, and technology transfer for small molecule oral dosage forms across development stages. You will drive enabling formulation strategies for challenging...PrincipalSenior
- ...Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects across preclinical to clinical... ...and agent orchestration to accelerate discovery and translation within Flagship's ecosystem. #J-18808-Ljbffr...Principal
$168k - $252k
...Vertex Pharmaceuticals seeks a Senior Principal Scientist to develop and deploy agentic AI systems for drug discovery. The role combines computational expertise with... ...engineering capabilities. Responsibilities Translate scientific requirements into autonomous...PrincipalSenior$268k - $384k
...'re building a talent-dense, high-agency AI safety team at Lila that will engage all... ...scientific systems. We are seeking a materials scientist to map risk across the material sciences... ...assessment of the risk landscape. Translate dual-use judgments into policy boundaries...PrincipalSeniorFull timeWork at officeLocal areaImmediate startFlexible hours$169.8k - $355.4k
...Infrastructure (OCI) Generative AI science team is responsible... ...work with teams of applied scientists and engineers to deliver high... ...and development efforts. As a Senior Principal Applied Scientist in Generative... ...health mandates, and/or drug testing requirements. Range...PrincipalSeniorTemporary workFlexible hours$117k - $201.25k
...Johnson & Johnson seeks a Principal Scientist to design an AI-reasoning platform for translational safety in drug discovery. The role focuses on developing multimodal AI systems and agent architectures that integrate scientific data across discovery, preclinical, clinical...Principal$115k - $215k
...on urgency and program impact.Translate key program questions into... ...recommendations to project teams, senior leadership, and external... ...decision making within fast-paced drug discovery environments.... ...organized, solutions-oriented scientist with the ability to manage multiple...PrincipalSenior$148.5k - $214.5k
Job title: Senior Principal Scientist Type 2 ImmunologyLocation:Cambridge, MAAbout... ...to join Sanofi's Translational Biology team as a Senior Principal... ...technical capabilities, including AI enabled platforms, single... ...engages patients early in drug development and uses their...PrincipalSeniorFull time$214.1k - $337k
Job DescriptionSenior Principal Scientist - Boston, MAOverviewWe are seeking a Senior Principal Scientist to provide scientific... ..., exposure-response, and translational decision-making.Provide scientific... ...development and application to drug discovery.Strong understanding...PrincipalSeniorFull timeFor contractorsLocal area$214.1k - $337k
...Merck seeks a Senior Principal Scientist to lead mass spectrometry capabilities within the Quantitative... ...across discovery programs to advance drug discovery decision-making.... ...mechanism, potency, selectivity, and translational decisions Provide scientific guidance...PrincipalSeniorLocal area$188k - $259k
About This Role Biogen is seeking a Sr. Principal Scientist, Oral Drug Product Development to provide scientific and strategic leadership for the development... ...commercialization. The Sr. Principal Scientistserves as a senior drug product leader and mentor on cross-functional CMC and...PrincipalSeniorFull timeTemporary workLocal area$160k - $235k
Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Boston, MA Salary Band: $160,000-$235,000 Location: Downtown Boston, MA Position Summary Antares Therapeutics is seeking to add an enthusiastic and highly motivated scientist...PrincipalSenior$173.2k - $272.6k
...an accomplished and highly motivated Principal Scientist to provide strategic and scientific biomarker... ..., analysis, and communication of translational and clinical biomarker strategies... ...medicine, neurobiology, biomarker science, drug development, or a related discipline....PrincipalFull timeFor contractorsLocal areaFlexible hours$255.8k - $402.7k
...have an exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development in the... ...discovery research, biostatistics, drug metabolism, modeling and simulation, regulatory...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours- ...Intelligence team in Cambridge, MA seeks a Principal Scientist to lead translational modeling and decision science. You... ...models to reduce uncertainty in drug development decisions and provide... ...will shape product requirements for AI-enabled translational tools, define...Principal
$114.1k - $211.9k
...is seeking a highly motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative... ...research, biomarker strategy, biomarker discovery, or drug development within the pharmaceutical or biotechnology industry...PrincipalFull timeLocal areaFlexible hours$130.8k - $209.4k
The Role:Moderna is seeking a Senior Scientist to join the Infectious Disease Research Immunology... ...team in Cambridge, MA. You will lead translational immunology studies that help teams understand... ...is a smoke-free, alcohol-free, and drug-free work environment.Pay & BenefitsAt...SeniorFull timeLocal areaWork from home$109k - $174.8k
...Senior Scientist position focused on developing AI and machine learning models for drug safety prediction across discovery, preclinical, clinical, and real-world evidence... ...validate, and deploy AI/ML solutions for translational safety prediction using multimodal data...Senior$93.8k - $174.2k
...advance the next generation of translational preclinical models for drug discovery. In this highly... ...suited to a collaborative scientist who enjoys troubleshooting... ...Job Title: Senior Scientist I/IIPosition Location... ...or Spotfire; exposure to AI-enabled analysis tools is...SeniorFull timeRelocation package
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior & Principal Scientist Translational AI for Drugs. Be the first to apply!
- research scientist machine learning deep learning Cambridge, MA
- image scientist Cambridge, MA
- health scientist Cambridge, MA
- regulatory scientist Cambridge, MA
- scientist biology Cambridge, MA
- drug safety scientist Cambridge, MA
- lead scientist Cambridge, MA
- principal applied scientist Cambridge, MA
- machine learning research scientist Cambridge, MA
- cell culture scientist Cambridge, MA



