Principal Statistical Analyst

Revolution Medicines is a late‑stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline comprises RAS‑(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS‑(ON) inhibitors daraxonrasib (RMC‑6236), a RAS‑(ON) multi‑selective inhibitor; elironrasib (RMC‑6291), a RAS‑(ON) G12C‑selective inhibitor; zoldonrasib (RMC‑9805), a RAS‑(ON) G12D‑selective inhibitor; and RMC‑5127, a RAS‑(ON) G12V‑selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity Position requires 14+ years of Statistical Programming experience with exploratory‑stage oncology clinical trials, providing programming support and oversight of one or more clinical programs (early or late phase) within Statistical Programming function. In addition to hands‑on programming, this position requires providing oversight and programming support and guidance for internal deliverables and regulatory submissions while ensuring conformance to CDISC standards and submission guidelines. Based on company needs, this position will be required to lead one or more early Phase or late phase studies/programs. Specific responsibilities include: Effective collaborating with cross‑functional teams to provide programming timelines for various deliverables. Provide SAS Programming technical support and guidance to programming team. Oversight/participation in any internal/mock or regulatory authority audits. Timeline and vendor management for deliverables, including submission‑related activities, complying with regulatory standards (e.g., FDA 21 CFR Part 11, GxP). Oversee the programming support for relevant deliverables, such as Investigator Brochures, publications, US and ex‑US regulatory submissions, including CDISC compliant datasets (SDTM, ADaM) and data documentation, Reviewer’s Guide, TLFs, Statistical Analysis Plans (study specific, ISS, ISE, Exposure‑Response), blank and annotated CRFs, and actual patient CRFs. Hands‑on programming and management of in‑house deliverables including but not limited to Dose Committee meetings, Board of Director meetings, Exploratory Analysis, etc. Oversight and Verification Review of documents, spreadsheets, slides for in‑house presentations and external publications. Titles may vary based on candidate experience. Required Skills, Experience and Education 14+ years of Statistical Programming experience with early or late phase oncology trial studies. BS/BA degree or other suitable qualification with relevance to the field. Experience leading one or more statistical programming contractors, and programming vendors. Proficiency in providing hands‑on SAS Programming support for production or validation of analysis datasets, tables, listings and figures. Demonstrated ability to multi‑task, prioritize options, anticipate challenges, and execute goals as a member of an interdisciplinary team is extremely important. Preferred Skills A demonstrable record of strong leadership and teamwork. Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high energy environment. Experience working in a small to mid sized biotech/pharma environment. Experience collaborating on development of processes, SOPs and guidance documents for the Statistical Programming function. The base pay salary range for this full‑time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job‑related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact View email address on click.appcast.io. Base Pay Salary Range

$186,000 - $233,000 USD

We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to View email address on click.appcast.io so we can share these impersonations with our IT team for tracking and awareness. #J-18808-Ljbffr Revolution Medicines