Synthetic Organic Chemist
Quadratic 3D, Inc.
We are seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation 3D printing resins . This position involves rapid exploration of chemical space through organic synthesis to develop photochemical and photophysical structure-property relationships. This role will be particularly appealing to chemists with a passion for both synthetic and physical organic chemistry. Our process uses a small amount of each lead candidate, so synthetic creativity is not limited by the scalability concerns that usually narrow the available chemical space in materials applications. Responsibilities Design, execute, and troubleshoot small molecule synthetic routes, with a focus on divergent or modular approaches to rapidly generate lead candidates. Characterize lead candidates via UPLC, NMR, UV/Vis and IR spectroscopy, and mass spectrometry. Contribute to the development of high-throughput analytical capabilities, small molecule databases, and virtual libraries. Work with cross-functional teammates to explore photochemical and photophysical structure–property relationships that drive 3D printing performance. Maintain excellent electronic lab notebook documentation. Minimum Qualifications PhD in Organic Chemistry or BS in Chemistry and 5+ years of experience in a small molecule discovery role. Strong expertise in both synthetic and physical organic chemistry, demonstrated through publications and other activities. Significant experience designing and executing multi-step synthetic routes. Extensive experience with modern computing and data analysis tools relevant to synthetic chemistry. Excellent communication, organizational, and time management skills. Demonstrated ability to independently drive an idea from conception to project completion. Evidence of strong collaboration and teamwork talents/skills. Strong publication record, both as lead author and as contributor to other projects . Preferred Qualifications Expertise in photochemistry and/or radical chemistry. Significant experience with synthesis of heterocyclic and/or extended aromatic systems, especially those relevant to organic (opto)electronics. Experience with cheminformatics and/or computational chemistry tools (e.g. DFT) relevant to the production of structure-property relationships. We offer competitive compensation packages in our VC-backed startup. Benefits include a full suite of offerings covering medical, dental, vision and 401k plan. Beautiful setting looking out over a river and seaport; outdoor seating and picnic areas. Highly collaborative work environment. Additional Information Travel: Occasional travel may be required from time to time We value diversity in our company and are an Equal Opportunity Employer. #J-18808-Ljbffr Quadratic 3D, Inc.
$66.8k - $124k
...Sciences team is seeking a Research Scientist to work as an organic medicinal chemist at Novartis’ Biomedical Research headquarters in Cambridge... ...of small molecules Analyze and interpret data, solve synthetic issues and design follow-up experiments Collaborate with...Suggested$110k - $170k
...your contributions to directly shape a company's trajectory, this could be a great fit. You'll be our first full-time synthetic organic chemist hire. You'll own the chemistry around and beyond the electrochemical step, from route design to characterized, written-up...SuggestedFull timeInternshipFlexible hours$115k - $165k
...house automated foundry for designing and building new organisms. Senior Engineer I, Computational Synthetic ChemistBoston, MassachusettsAbout Ginkgo... ...Small Molecules team is looking for a synthetic organic chemist to support computationally enabled synthetic chemistry...SuggestedWork at office$45 - $49.5 per hour
Yoh Life Sciences is seeking an Organic Chemist / Platform Chemistry Scientist to support a leading pharmaceutical company's Encoded Technologies... ...experimental chemist who can independently plan and execute synthetic chemistry experiments, troubleshoot challenging reactions,...SuggestedContract workMonday to Friday$66.8k - $124k
Job Description Lab-based role carrying out multi-step organic chemistry synthesis routes to prepare organic molecules testing molecular... ...of small molecules. Analyze and interpret data; troubleshoot synthetic issues; design follow-up experiments. Collaborate effectively as...Suggested$50 per hour
...into an innovative lab environment in Cambridge, MA, with a top-tier global pharmaceutical leader. We are seeking a dedicated Organic Chemist to join the Encoded Technologies team onsite, playing a key role in advancing on-DNA binder confirmation platforms and driving...Hourly payContract workTemporary workWork experience placement- Scorpion Therapeutics in Cambridge, MA is seeking chemists to perform multi-step organic syntheses and data-driven analysis to test disease-related hypotheses. You will apply mechanistic chemistry and modern methods, purify products, and confirm structures by characterization...
- ...leading advanced materials firm is seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation... ...should possess a strong background in synthetic and physical organic chemistry and demonstrate excellent collaboration skills....
- ...Cambridge, MA 02140 Fully onsite Duration: 09/16/2026 to 09/10/2027 Shift: 9:00 AM - 5:00 PM EST We are currently looking for an Organic Chemist to join our team in Cambridge, MA. The primary focus of this role is to support our on-DNA binder confirmation platform and on-...Work at officeShift work
- LanceSoft, Inc. in Cambridge, MA is seeking an Organic Chemist to join our onsite team to support our on-DNA binder confirmation platform and on-DNA reaction optimization. The role emphasizes synthesizing on-DNA compounds, developing DNA-compatible reactions for DNA-encoded...Work at office
- Ginkgo Bioworks is seeking a Senior Engineer I in Computational Synthetic Chemistry to design and execute multi-step syntheses of novel... ...into practical workflows. You will mentor junior chemists, evaluate predictions, and feed outputs back into planning to...
- Ginkgo Bioworks in Boston, MA seeks a Senior Engineer I, Synthetic Chemistry to design and execute multi-step syntheses of novel drug-like molecules, including singleton analogs and small focused sets that cannot be made in plate format. You will own route selection, execution...
- Novartis is seeking a Research Scientist I/II to join the Discovery Sciences team as an organic medicinal chemist at our Biomedical Research headquarters in Cambridge, MA. In this lab-based role you will design and execute multi-step syntheses, optimize routes, and use...
- Novartis Discovery Sciences in Cambridge, MA seeks a Research Scientist to perform organic medicinal chemistry in a lab-based role, designing and synthesizing small molecules to test biological hypotheses and interrogate disease pathways. The position is onsite and involves...
- ...to optimize metabolic flux in sugar polymer biosynthesis through fermentation and computational methods. You will collaborate with Synthetic Biology and Polymer Chemistry teams to improve production strains and methods, while documenting results and contributing to IP...
- ...polymer biosynthesis pathways. Create experimental workflows to perform fermentation and collect data. Collaborate frequently with the Synthetic Biology and Polymer Chemistry teams to optimize sugar polymer biosynthesis pathways in the production strains. Communicate methods...Full timeInternship
- Novartis is seeking a Medicinal Organic Chemist in Cambridge, MA to join the Discovery Sciences unit. The role focuses on designing and synthesizing small molecules that test biological hypotheses, using modern purification and analytical methods in a lab-based setting....
- ...safely, rapidly, and cost effectively. Summary We are seeking a synthetic chemist to lead small-scale chemistry characterization and... ...things Required Qualifications B.S., M.S., or PhD in Chemistry, Organic Chemistry, Catalysis, or a related discipline 5+ years of professional...Permanent employment
$125.19k - $208.65k
Job DescriptionJoin Agilent in driving advancements that improve the quality of life globally. As a leader in life sciences, diagnostics, and applied markets, Agilent provides innovative instruments, services, and expertise that empower laboratories worldwide. We seek a...Full timeLocal areaRemote workWorldwide- Adiabatic Materials is building a novel electrochemical synthesis platform in Somerville, MA. You will own chemistry around and beyond the electrochemical step, from route design to documented results, working directly with the Chief Scientific Officer and founders. We ...
$100k - $126.5k
...modality. We are pioneering the development of Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional scientists who are passionate about driving therapeutic...- Job title : Senior Analytical Chemist - Solid State Characterization Location: Cambridge, MA About The Job Sanofi is seeking a highly... ...for Solid State Characterization. The group is part of the synthetic platform within Global CMC Development that is striving to become...
$150k - $200k
...Job Description Job Description Synthetic Chemist - Develop the chemistry behind next-generation energetics manufacturing Waltham, Massachusetts... ...~ Bachelor's, Master's, or PhD in Chemistry, Organic Chemistry, Synthetic Chemistry, Catalysis, or a related field...- Boston University seeks a Mass Spectrometry Instrumentation Specialist to oversee the operation of shared MS instruments in the Chemical Instrumentation Center. The role provides technical and scientific support to faculty, students, staff, and other researchers, helping...
- ...workflows and collect quantitative measurements using GPC, SEC, DSC, HPLC, and FTIR. You will collaborate with Metabolic Engineering and Synthetic Biology teams to optimize production strains, communicate results internally and externally with scientists and industry partners,...
- ...ELISA, gene expression analysis, western immunoblotting, and RNAi.• Basic knowledge of statistics and experimental design Excellent organization, communication, and presentation skills High level of initiative in performing experiments, multi-tasking and troubleshooting...Immediate start
- Massachusetts General Hospital is seeking a Sr. Research Lab Tech to join the laboratory of Thierry Nordmann, MD, PhD. The role focuses on running and maintaining the lab's mass spectrometry platform and executing cutting-edge workflows in inflammatory skin disease. Ideal...
$37 - $41 per hour
Eurofins CDMO Alphora Inc is seeking a highly skilled scientist to join their Analytical Development team in Boston, MA. This full-time role involves testing non-GMP samples, developing analytical methods, and providing testing support for product characterization and stability...Hourly payFull time$37 - $41 per hour
Job Description Eurofins is seeking a highly skilled, passionate, and motivated scientist to join our client Analytical Development team to support testing non‑GMP samples for development studies such as comparability assessments, process development, stability, product...Hourly payFull timeMonday to FridayDay shift- Biognosys, an entity of Bruker Scientific, established a Newton, MA laboratory to offer proteomics and metabolomics services. We seek a motivated Research Associate to support sample preparation and LC-MS/MS data acquisition, ensuring compliance with our quality standards...
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