Senior Scientist, DMPK & PK for RNA Therapeutics
Wave Life Sciences
Wave Life Sciences is seeking a highly motivated Scientist with expertise in bioanalytical and DMPK sciences to support RNA‑based drug programs from preclinical to clinical stages. This hybrid role is based in Lexington, MA and involves designing and interpreting PK/TK studies across cross‑functional teams. The ideal candidate will have a PhD or MS with significant industry experience, strong PK/PD knowledge, and experience with PK software tools. #J-18808-Ljbffr Wave Life Sciences
- Lilly, together with Orna Therapeutics, Inc., a Lilly subsidiary based in Watertown, MA, is seeking a Senior Principal Scientist to drive analytical characterization of circular RNA and lipid nanoparticle‑based therapeutics using LC‑MS/MS. You will partner with Platform...Senior
- Lilly is seeking a Senior Principal Scientist to drive analytical characterization of circular RNA and lipid nanoparticle-based therapeutics with a focus on mass spectrometry. The candidate will develop and qualify LC-MS/MS assays and lead method transfer to partners in...Senior
- Monte Rosa Therapeutics Inc. in Boston is seeking an experienced DMPK and ADME Scientist to lead efforts in the discovery and development of drug pipelines. The role involves close collaboration with medicinal chemistry teams and managing external collaborations, thus critical...Senior
$157k - $213k
...the broad potential of RNA medicines to transform... ...motivated and detail-oriented Scientist with strong expertise... ...and Pharmacokinetics (DMPK) sciences to support... ...interpreting pharmacokinetic (PK), toxicokinetic (TK),... ...advancement of RNA therapeutic programsAutonomously...SeniorTemporary workSummer workWork at officeLocal area$179k - $236k
...Scientific Officer, this role leads DMPK and bioanalytical strategy... ...DMPK and bioanalytical scientist with experience in PK study design, bioanalytical... ..., or nucleic acid / RNA therapeuticsFamiliarity with... ...indications. The company’s initial therapeutic programs are designed to...Senior$119.7k - $222.3k
...enthusiastic and motivated PK Sciences representative... ...molecules, biologics/therapeutic proteins, antibody drug... ...role overseeing ADME/DMPK project strategy in clinical... ...for Principal Scientist II. 4+ years of experience... ...experience to be considered for Senior Principal Scientist....SeniorFull time$119.7k - $222.3k
...enthusiastic and motivated PK Sciences representative... ...molecules, biologics/therapeutic proteins, antibody drug... ...role overseeing ADME/DMPK project strategy in clinical... ...for Principal Scientist II. 4+ years of experience... ...experience to be considered for Senior Principal Scientist....Senior$119.7k - $222.3k
...enthusiastic and motivated PK Sciences representative... ...molecules, biologics/therapeutic proteins, antibody drug... ...role overseeing ADME/DMPK project strategy in clinical... ...for Principal Scientist II. 4+ years of experience... ...experience to be considered for Senior Principal Scientist....Senior$129k - $203.1k
...Bioanalytics (PDMB) is seeking a curious and collaborative Senior Scientist for our growing Translational PK/PD organization. The Translational PK/PD Senior... ...strategy with a focus on biologics, protein therapeutics, and peptides.The Translational PK/PD Senior Senior...SeniorFull timeFor contractorsLocal areaFlexible hours- Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, seeks a Senior Principal Scientist to drive analytical characterization of circular RNA and LNP-based therapeutics, focusing on LC‑MS/MS methods and cross‑functional collaboration in a fast-paced...Senior
- ...of transformative precision allosteric therapeutics to address serious unmet patient needs... ...Position Summary: We are seeking a Senior Scientist, DMPK, to join our R&D group and work with an... ...and external audiences. Propose ADME/PK, biodistribution and PK-PD approaches...SeniorFlexible hours
- Noara Therapeutics, Cambridge, MA, is seeking a Senior Scientist or Scientist with deep expertise in cell biology, immunology, and assay development to lead the... ...biology, automation, and data science teams to develop scalable assays for our RNA‑LNP #J-18808-Ljbffr C10 LabsSenior
- Moderna Therapeutics in Cambridge, MA, seeks a Senior Research Associate to advance RNA modification biology within the RNA Innovation team. This lab-based role focuses on designing experiments to understand how RNA modifications affect RNA metabolism and performance. The...Senior
- ...using its proprietary RNA editing platform.... ...seeking a highly motivated Senior Associate Scientist to join our In Vivo... ...or more experimental therapeutic compounds. Serve as... ...pharmacokinetic/pharmacodynamic (PK/PD) relationships.... ...Biology, and DMPK teams to support exposure...SeniorWork at officeFlexible hours
$176.2k - $277.3k
...and collaborative Principal Scientist (director-level equivalent) to... ...metabolism and pharmacokinetic (DMPK) efforts across multiple... ...such as peptides and protein therapeutics as a project-team representative... ...and interpretation of PK and PK/PD data sets and through...Full timeFor contractorsLocal areaWorldwideFlexible hours$145k - $161k
...portfolio of investigational therapeutic programs organized around our... ...enthusiastic, self-motivated Senior Scientist to join the Nonclinical Development... ...with Pharmacology, DMPK, and other functions to support... ...delivery approaches, Lipid and RNA components, and emerging targets...SeniorFull timeTemporary workFlexible hours$98.7k - $183.3k
Job Description SummaryLI#-Onsite (Lab Based)Internal Title: Senior Scientist IILocation: CambridgeThis role is based in Cambridge, MA. Novartis... ...internal lab based bioanalytical support investigating the PK/TK properties of low molecular weight and novel modality compounds...SeniorFull timeLocal areaShift work- Monte Rosa Therapeutics is seeking an experienced DMPK and ADME Scientist to lead efforts in the discovery and development of drug pipelines. The role involves close collaboration with the medicinal chemistry team to ensure optimal drug properties and involves managing...
- Monte Rosa Therapeutics, Inc is looking for an experienced DMPK and ADME Scientist to lead efforts in drug discovery and development. The successful candidate will collaborate across teams to ensure optimal drug pipeline progression, overseeing all aspects of DMPK assessments...
- Prime Medicine is recruiting a Senior Scientist to join the Platform Technology & Innovation team in Cambridge, MA. You will design and engineer RNA components for Prime Editing systems, translating deep RNA biology expertise into platform-level advances with translational...Senior
- Prime Medicine is seeking an exceptionally driven Senior Scientist for the Platform Technology & Innovation team. This role focuses on RNA component design for Prime Editing systems, applying molecular biology and editing expertise to tackle platform-level challenges with...Senior
- Strand Therapeutics, a Boston-based biotech, seeks a Senior/Principal Associate Scientist to join the mRNA Programming group, advancing RNA LNP therapeutics in oncology and beyond. You will lead experiments, drive discovery, and collaborate across teams to shape next-generation...Senior
- Moderna, based in Cambridge, MA, seeks a Senior Research Associate for the RNA Innovation team to study the chemical biology of mRNA and how RNA modifications affect metabolism and performance. The role involves designing experiments using in vitro biochemistry and cell...Senior
- ...that are capable of working across multiple therapeutic areas and drug modalities. We are... ...of target‑specific in vivo pharmacology, PK/PD, and safety assessments throughout our... ...rapid, reliable preclinical efficacy data. DMPK and Toxicology: To align in vivo efficacy...SeniorContract workWork at office3 days per week
$126k - $234k
...Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal ScientistLocation: Cambridge... ...eager to accelerate oligonucleotide therapeutics (xRNA”), including antibody-xRNA... ...• Build and apply mechanistic models (PK/PD, QSP, and PBPK/PD) that link drug pharmacology...SeniorFull time$148k - $203.5k
...creative strategic alliances that accelerate therapeutic innovation by bringing together... ...accomplished and highly collaborative Senior Principal Scientist, In Vitro Pharmacology to lead the development... ...data with in vivo efficacy, PK/PD, and systems biology datasets to guide...Senior$105.04k - $127.29k
## Senior Associate Scientist, In Vivo Pharmacology, Oncology Discovery BiologyCambridge... ...of novel oncology therapeutics for patients. Centered at our... ...engineering/antibody development, DMPK and translational group.... ...in vivo efficacy and PK/PD studies and experiments...SeniorHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work- The client is seeking an experienced Senior Scientist to join their Bioanalytical Sciences team... ...IND-enabling studies for our mRNA-LNP therapeutics. You will be a subject matter expert in... .... You will report into the VP, Head of DMPK and Clinical Pharmacology, with the expectation...Senior
$89.6k - $166.4k
...OnsiteLocation: CambridgeInternal Title: Senior Scientist ISupport discovery and development... ...metabolic stability and permeability to support PK Science’s strategies.Interpret in vitro... ....BSc: 7+ years; MSc: 4+ years of ADME/DMPK experience.Experience working in a drug...SeniorFull time$137k - $215.27k
...Cambridge, MAPOSITION: Research Senior ScientistPOSITION DESCRIPTION... ...is seeking a Research Senior Scientist in Cambridge, MA with the following duties: serve as the DMPK representative on projects to... ...vivo studies to drive novel therapeutic development including animal...SeniorMinimum wageFull timeTemporary workWork at officeLocal area
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