Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal / Senior Principal Biostatistician

$119.7k - $222.3k

Development

Summary

#LI-Hybrid 
Location: Cambridge, USA 

This role is based in Cambridge, USA. Novartis is unable to offer relocation support for this role. Please only apply if this location is accessible for you.  

We are in search of a Principal or Senior Principal Biostatistician to join a passionate team in early phase drug development. Come to an industry leader where you will lead implementation of modern and innovative trial/experimental designs, statistical models, and analysis and data exploration methodologies at the study or project level, and you will be responsible for all statistical work, scientific and operational, in collaboration with the clinical trial teams and other quantitative partners in the Early Development – Advanced Quantitative Science's team.

About the Role

Your Key Responsibilities:

  • Responsible for all statistical tasks on the assigned trials.
  • Protocol development in alignment with the development plan, developing statistical analysis plan, reporting activities.
  • Contribute to planning and execution of statistical analyses and statistical consultation within your cross-functional teams.
  • Initiate, drive and implement novel methods and innovative trial designs in alignment with the Lead Statistician.
  • Collaborate with clinical, regulatory and other strategic functions to drive quantitative decision making in assigned indications/program with oversight.
  • Collaborate cross-functionally (e.g., data management, programming, medical writing) to ensure timeliness and quality of statistical deliverables.
  • Contribute to external engagement with consultants, advisory boards, health authorities, congresses, and scientific meetings.

Essential Requirements:

  • PhD in Statistics, Biostatistics, or a related quantitative field preferred or MS with extensive experience. Principal or Senior Principal Biostatistician, level commensurate with experience.
  • Fluent English (oral and written).
  • Strong communication and presentation skills.
  • Proficiency in R and/or SAS

Novartis Compensation Summary:

The salary for this position is expected to range between $119,700.00 - $222,300.00 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a 

variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here .

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?

Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call View phone number on us.fitly.work and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Principal / Senior Principal Biostatistician in Cambridge, MA vacancy
  • $151k - $215k

     ...driving force to help patients live longer and healthier lives. Join us and be part of our inspiring journey. The Senior Principal Biostatistician (Epidemiology) will represent the Biostatistics department on all aspects of the clinical development process, ranging... 
    Principal
    Senior
    Full time
    Remote work

    Edwards Lifesciences

    Boston, MA
    2 days ago
  • $203k - $247k

    The OrganizationWhat's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible...
    Principal
    Work at office
    Local area
    Remote work

    Entrada Therapeutics

    Boston, MA
    2 days ago
  • $123k - $163k

    About This Role: As a Principal Biostatistician, you will provide project leadership in Biostatistics for specific company products or therapeutic areas. You will play a pivotal role in developing standards across protocols, including protocol development, analysis plans... 
    Principal
    Full time
    Temporary work
    Local area
    Worldwide

    Biogen Idec

    Cambridge, MA
    1 day ago
  • $132.2k - $198.2k

    Job DescriptionGeneral Summary:The Senior Biostatistician II will perform scientific statistical analyses in support of the company's Global Medicines Development and Affairs area with guidance and mentoring on new and complex issues. The incumbent will complete assigned... 
    Senior
    Full time
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    3 days ago
  •  ...Senior Principal StatisticianA healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people... 
    Principal
    Local area

    Genentech

    Boston, MA
    5 days ago
  • Job TitlePROMETRIKA is a full-service clinical research organization (CRO) with extensive experience in clinical operations, data management, biostatistics, medical writing, and pharmacovigilance. We're driven by our passion for the human aspect of our work and our compassion...
    Principal
    Work experience placement

    Prometrika

    Cambridge, MA
    6 days ago
  • $156k - $234k

     ...Senior Principal Statistician, BiostatisticsThe Senior Principal Statistician, Biostatistics will be a lead statistician on individual studies, across related studies, and for integrated summaries and will design and report Phase I to IV clinical studies and regulatory... 
    Principal
    Flexible hours

    American Statistical Association - ASA

    Boston, MA
    4 days ago
  • Brigham and Women's Hospital, Inc. seeks a doctoral-level Senior Computational Scientist to provide intermittent leadership for epigenomics projects and to maintain a proprietary set of analytical frameworks. This per-diem role supports manuscripts in revision and publication... 
    Principal
    Daily paid

    Brigham and Women's Hospital, Inc.

    Boston, MA
    3 days ago
  •  ...Who Are You? An experienced Principal Biostatistician with a passion for clinical development and analysis, adept at utilizing advanced statistical methods, you will lead one Phase I-IV clinical studies across your region. You are excited and enthusiastic, motivate... 
    Principal
    Full time

    Cytel

    Cambridge, MA
    more than 2 months ago
  • Responsibilities Manage a moderate or large volume of complex tasks with minimal supervision across one or more drug programs Proactively assess and adapt solutions for the Biometrics department, resolving technical issues Make decisions at the study level across various...
    Principal
    Worldwide

    Jobtailor

    Cambridge, MA
    3 days ago
  • $116k - $151k

     ...forge new paths as we move toward a common goal of elevating science and service for rare patients. Position Summary: The Senior Biostatistician will work under the general direction of the Associate Director, Biostatistics in providing statistical support to Health... 
    Senior
    Temporary work
    Remote work

    Travere Therapeutics

    Boston, MA
    1 day ago
  • $59.1k

     ...Maximus is currently seeking a Senior Biostatistician The Senior Biostatistician supports the short- and long-term well-being of SOF warriors and their families by applying advanced analytical expertise to human performance programs. This role uses mathematical and... 
    Senior
    Contract work
    Temporary work
    Remote work

    MAXIMUS

    Boston, MA
    2 days ago
  • Cytel Inc. is seeking an experienced Principal Biostatistician to drive statistical leadership across Phase I-IV trials. You will embed with a sponsor, influence clinical development plans, and guide analyses from concept to reporting using SAS and R. This role emphasizes... 
    Principal
    Remote job

    Cytel Inc.

    Cambridge, MA
    3 days ago
  • Entrada Therapeutics is seeking a senior statistician to lead daily statistical activities and shape methodologies for multiple trials. You will collaborate with internal/external teams to manage a growing portfolio and advance the biostatistics function in a fast-paced... 
    Senior
    Remote job

    Entrada Therapeutics

    Boston, MA
    3 days ago
  • $325 per month

     ...Hispanic, Latino, African American, or Two or More Races 64% Of our Senior Leadership Team and Board is made up of women and minorities...  ...to know that what you do every day matters.” Haoming Liu, PhD Principal Scientist, Discovery Biology Picture Yourself at Entrada... 
    Principal
    Remote job
    Freelance
    Work at office
    Local area
    Flexible hours

    Entrada

    Boston, MA
    3 days ago
  • $56.59 - $82.31 per hour

     ...join us and experience what it means to be part of Mass General Brigham. Job Summary The Chai Laboratory seeks a doctoral-level Senior Computational Scientist to provide specialized, intermittent computational leadership to an active portfolio of epigenomics and... 
    Principal
    Hourly pay
    Daily paid
    Full time
    Part time
    Immediate start
    Remote work
    Shift work

    Mass General Brigham

    Boston, MA
    13 days ago
  • Vertex Pharmaceuticals LLC in Boston, MA, seeks a Senior Biostatistician II to lead statistical analyses in Global Medicines Development and Affairs, applying SAS and R to trial design and data interpretation. Flexibility in hybrid work is available; the role emphasizes... 
    Senior

    Vertex Pharmaceuticals LLC

    Boston, MA
    2 days ago
  • The Chai Laboratory at Mass General Brigham seeks a doctoral-level Senior Computational Scientist to provide intermittent computational leadership for epigenomics and hematologic malignancy projects. This per diem role maintains production research software and serves... 
    Senior
    Daily paid

    Mass General Brigham Incorporated

    Boston, MA
    4 days ago
  • Foundation Medicine in Boston, MA seeks a Sr Biostatistician to lead statistical analysis and data science for development and validation of cancer diagnostic devices. You will ensure robust study designs, timely data analyses, and high-quality regulatory documents while... 
    Senior

    Foundation Medicine

    Boston, MA
    1 day ago
  • Vertex Pharmaceuticals is seeking a Senior Biostatistician II in Boston to perform scientific statistical analyses in support of Global Medicines Development and Affairs. You will design and execute the statistical infrastructure for clinical trials, observational studies... 
    Senior

    Vertex Pharmaceuticals Inc (US)

    Boston, MA
    1 day ago
  • Vertex Pharmaceuticals in Boston, MA, is seeking a Senior Biostatistician II to lead scientific statistical analyses within Global Medicines Development and Affairs. You will design trials, evaluate data, and mentor teammates in statistical thinking. PhD or MS in Statistics... 
    Senior

    Vertex Pharmaceuticals

    Boston, MA
    2 days ago
  • Reference: 628547Posted: 2026-07-27Location: Boston, MassachusettsCompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts...
    Principal
    Senior

    Planet Pharma

    Boston, MA
    1 day ago
  •  ...about our exciting opportunities and why MMS is a great place to advance your career. Visit or follow MMS on LinkedIn . Senior Biostatistician: Responsibilities:  Create randomization and kit schedules independently, collaborate with sponsor, randomization and... 
    Senior
    Full time
    Remote work

    MMS

    Boston, MA
    more than 2 months ago
  •  ...Hasbro is hiring a Senior Principal, Technical Product Manager to translate complex workflows into scalable automation and AI-enabled capabilities that drive real business value across Marketing, Brand, and Commercial teams worldwide. This hands-on, globally oriented... 
    Principal
    Senior
    Temporary work
    Worldwide

    Hasbro

    Boston, MA
    2 days ago
  • $261k

    Atlanta Austin Boston Charlotte Chicago Cleveland Columbus Connecticut - Darien Dallas Denver Detroit Do you want to do work that matters, alongside supportive leaders who will help you grow faster than you ever thought possible? Are you a creative problem-solver...
    Senior
    Hourly pay
    Part time
    Apprenticeship
    Work at office
    Easy work

    McKinsey & Company

    Boston, MA
    5 days ago
  • Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, seeks a Senior Principal Scientist to drive analytical characterization of circular RNA and LNP-based therapeutics, focusing on LC‑MS/MS methods and cross‑functional collaboration in a fast-paced... 
    Principal
    Senior

    Eli Lilly and Company

    Watertown, MA
    4 days ago
  •  ...The Position Senior Principal Statistician A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more... 
    Principal
    Senior
    Local area

    Genentech

    Boston, MA
    5 days ago
  •  ...Senior Director, Principal Gifts About the Company Philanthropic organization supporting Indigenous culture & individuals Industry Non-Profit Organization Management Type Non Profit Founded 2017 Employees 11-50 Categories ~ Non-Profit &... 
    Principal
    Senior

    Confidential

    Boston, MA
    2 days ago
  • Klaviyo in Boston area is seeking an R&D Recruiting Lead to serve as the senior recruiting partner for the business. You will build hiring plans, run critical searches, advise leaders on talent strategy, and raise the overall quality of recruiting across the team. This... 
    Principal
    Senior

    Socket.dev

    Boston, MA
    1 day ago
  •  ...Kennedy School in Cambridge, MA seeks an experienced Director, Principal & Major Gifts to manage a 75-100 prospect portfolio and lead fundraising...  ...for School priorities. You will work closely with faculty, senior administration and University officials to identify, qualify,... 
    Principal
    Senior

    Harvard University

    Cambridge, MA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal / Senior Principal Biostatistician. Be the first to apply!