Principal Translational Toxicologist & Safety Lead
F. Hoffmann-La Roche AG
Genentech, a member of the Roche group, seeks a Principal Scientist to provide scientific leadership across drug development, from discovery to clinical stages. You will synthesize toxicology data, shape safety strategies, and supervise safety studies in collaboration with pathologists, translational scientists, and clinicians. The role emphasizes timely decision-making, weight-of-evidence analyses, and early regulatory interactions to enable program progression. #J-18808-Ljbffr F. Hoffmann-La Roche AG
$173.1k - $321.5k
...Translational Safety Toxicologists provide scientific leadership across drug development, from early research... ...and marketed products. This Senior Principal Scientist role is intended for an... ...environment, the Senior Principal Scientist leads the safety assessment of Genentech...PrincipalFull timeLocal areaImmediate startRelocation package3 days per week$155k - $200k
...of unprecedented scale. This Position NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development. In this role, you will lead the discovery, development, and qualification of pharmacodynamic (PD...Principal$190.8k - $300.3k
...seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific... ...Diseases/Vaccines portfolios. This role will lead the design, execution, analysis, and communication of translational and clinical biomarker strategies across programs...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$110k - $140k
Job Description The Site Safety & Compliance Lead serves as the senior safety representative for an assigned market, creating a safe, compliant... ...conducting operational compliance or quality audits and translating findings into practical corrective actions Strong safety...SuggestedLocal area- ...a Senior Research Associate / Associate Scientist to support Translational Biology from early discovery through IND-enabling studies. You... ..., execute, and analyze in vitro and ex vivo assays to advance lead candidates and support immunology-driven programs. Ideal candidates...Suggested
$147.8k - $274.4k
...highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the... ...group in the Department of AI for Biology & Translation (AIBT) in Genentech Research and Early... ...ideas. The candidate is expected to lead high profile projects in collaboration with...PrincipalFull timeLocal areaWorldwide$268k - $384k
...yourself and report honestly when a contribution adds nothing. Co-design with ML scientists, mechanism scientists and engineers, translate model output into decisions people actually make, and publish — what is and is not predictable from mechanistic and human evidence...PrincipalFull timeWork at officeLocal areaFlexible hours$143.29k - $266.11k
...and media optimization. As a member of this team, you will lead cutting-edge efforts to develop and optimize cell culture media... ...on state-of-the-art cell therapy media development practices, translating deep scientific expertise into strategic innovations that enable...PrincipalLocal areaRelocation package$150k - $180k
We are seeking a Senior/Principal Scientist to lead the bioanalytical/analytical characterization of our oligonucleotide therapeutics. The role... ..., through method development and data interpretation, to translating findings for project teams. It is a hands-on role that...PrincipalFull time$260.3k - $409.7k
...Description Description of Position Translational Medicine is responsible for early... ...Cardiovascular Disease and related conditions. The Principal Scientist (Clinical Director) must have... ...clinical and biomarker plans for Lead Optimization programs, early clinical development...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$173.1k - $321.5k
...the people we love. The Senior Principal Scientist serves as the... ...Bioanalytical Sciences, Research, Translational Medicine, Clinical... ...to efficacy, durability, and safety. Working collaboratively across... ...Bioanalytical Sciences project leads to developing integrated bioanalytical...PrincipalLocal areaRelocation package- Genentech’s Investigative Toxicology group within Translational Safety advances science to elucidate safety liabilities across Neuroscience and... ...Scientist will drive strategy, develop preclinical safety roadmaps, lead matrixed studies, and collaborate with predictive toxicology,...
- NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development to lead PD biomarker assays that characterize the biological activity of our mRNA-LNP medicines in preclinical and IND-enabling studies...
- Google is seeking a Regulatory Operations Specialist for YouTube Trust and Safety in San Bruno, CA / Mountain View, CA. The role focuses on handling legal and regulatory escalations and ensuring compliant processes for emerging content regulations. You will work with cross...
- OpenAI is hiring a Model Policy Manager focused on the safety of multimodal models. You will shape how OpenAI identifies, evaluates,... ...design policies for audio, image, video, and omni-modal behavior, translate harm theories into measurable criteria, and partner with...Relocation package
- Alvah Contracting LLC is seeking a Field Safety Specialist to support field operations across construction sites in California. You will... ...conducting JHAs, risk assessments, safety audits, and leading incident investigations, with a focus on proactive safety culture...
- See’s Candies in South San Francisco, CA, seeks a Sanitation Supervisor to lead the sanitation team and ensure strict adherence to safety and food safety procedures. The role supports scheduling, training, and program improvements, with a focus on quality and compliance...Afternoon shift
- ...antibody discovery and development for autoimmune disease. We seek a Senior Research Associate / Associate Scientist to join our Translational Biology team, supporting autoimmunity programs from discovery through IND-enabling studies. The role involves designing,...
$163k - $196k
...Principal Data Scientist InterVenn South San Francisco, CA, US Job Type: Full-Time... ...across oncology indications Lead exploratory research into new quantification... ...relying on protein-quantity signal alone Translate emerging techniques from the ML, AI, and...PrincipalFull time- Genentech in South San Francisco, CA is seeking a highly motivated scientist to lead pharmacology efforts within the CVRM Translational Biology group. The role focuses on driving drug discovery and mechanistic studies, coordinating multidisciplinary teams to advance candidates...
- Nurix Therapeutics, Inc. is seeking a Senior Director of Translational Medicine and Clinical Biomarkers to own the biomarker strategy across... ...expertise in immunology, oncology, or hematology. You will lead assay development and team growth, partnering with clinical development...
- Genentech is seeking a Senior Scientist in translational PKPD to advance preclinical ADME/PKPD studies and support INDs/BLAs under supervision. The role involves independent design, data interpretation, and collaboration with Clinical Pharmacology, Biochemical Sciences...Relocation package
- MSD in South San Francisco, CA seeks a Translational PK/PD Associate Director to lead modeling for biologics and protein therapeutics. You will independently design analyses guiding drug discovery strategy and dose prediction in cross-functional teams. Work with in vitro...
- ...experiences for everyone. Why Safety? At Roblox, we strive to... ...AI Systems? As a Senior/Principal Machine Learning Engineer... ...Safety ML pillar. You will lead and scale a high-performing group... ...planning ability: able to translate platform safety requirements...PrincipalFull time
- Genentech, a Roche company, is advancing Biological Research | AI Development (BRAID) within AI Biology & Translation. We seek a Scientist/Senior Scientist with strong computational and data-science foundations to develop AI methods that translate into biological and clinical...
$143.2k - $265.9k
...The Position The Opportunity SE7 As a Principal Scientist in Small Molecule Biomarkers (Metabolomics & Lipidomics) within our... ...Partner with multidisciplinary teams and project stakeholders to translate complex omics data into actionable drug target research....PrincipalLocal areaRelocation package- Genentech in South San Francisco seeks a scientist to drive preclinical and translational imaging research, bridging in vivo experiments, MRI/PET operations, and AI-enabled workflows to turn imaging data into therapeutic insights. You will design and execute imaging studies...
- Genentech, a member of the Roche group, seeks a highly skilled imaging scientist to drive preclinical and translational imaging research. You will work across in vivo experiments, scanner operations, quantitative analysis, and AI-enabled workflows to translate imaging data...
- Genentech is seeking a Senior Scientist in the translational Pharmacokinetics and Pharmacodynamics (tPKPD) team within gRED to advance PKPD science for biologics across its pipeline. You will design and execute in vitro and in vivo ADME/PKPD studies, generate regulatory...Relocation package
$153.3k - $284.7k
...Medical Data Review (MDR) and safety signal detection, aligned... ...The Early Development Principal Statistician is a critical partner... ...development strategy. ● You lead the statistical design of complex... ..., such as integrating translational data, navigating sparse or emerging...PrincipalLocal areaRelocation package
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