Principal Translational Toxicologist & Safety Lead
F. Hoffmann-La Roche AG
Genentech, a member of the Roche group, seeks a Principal Scientist to provide scientific leadership across drug development, from discovery to clinical stages. You will synthesize toxicology data, shape safety strategies, and supervise safety studies in collaboration with pathologists, translational scientists, and clinicians. The role emphasizes timely decision-making, weight-of-evidence analyses, and early regulatory interactions to enable program progression. #J-18808-Ljbffr F. Hoffmann-La Roche AG
- Genentech in South San Francisco, CA is seeking a Senior Principal Scientist to lead translational safety across multiple development programs, including novel modalities. The role requires integrating toxicology, pathology, pharmacology, translational and clinical data...Principal
- Genentech is seeking a Senior Principal Scientist in Translational Safety to provide scientific leadership across drug development, from discovery to clinical stages. This role leads independent toxicology and safety programs for multiple development projects, integrating...Principal
- Genentech, located in South San Francisco, seeks a Senior Principal Scientist in Translational Safety to provide scientific leadership across drug... ...to shape strategy and enable timely decisions. You will lead cross-functional teams, design safety programs, mentor...Principal
$173.1k - $321.5k
The PositionTranslational Safety Toxicologists provide scientific leadership... ...products. This Senior Principal Scientist role is intended... ..., pathology, pharmacology, translational, and clinical information to... ...Senior Principal Scientist leads the safety assessment of Genentech...PrincipalFull timeLocal areaImmediate startRelocation package3 days per week$173.1k - $321.5k
The Position Translational Safety Toxicologists provide scientific leadership across drug development, from... ...and marketed products. This Senior Principal Scientist role is intended for an experienced... ..., the Senior Principal Scientist leads the safety assessment of Genentech...PrincipalLocal areaImmediate startRelocation package3 days per week- Genentech is seeking a Principal Scientist in Translational Safety located in South San Francisco. The role focuses on providing scientific leadership across drug development, leading safety assessments, and shaping strategies for multiple development programs, including...
$147.8k - $274.4k
...highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the... ...group in the Department of AI for Biology & Translation (AIBT) in Genentech Research and Early... ...ideas. The candidate is expected to lead high profile projects in collaboration with...PrincipalFull timeLocal areaWorldwide$155k - $200k
...of unprecedented scale. This Position NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development. In this role, you will lead the discovery, development, and qualification of pharmacodynamic (...Principal- Genentech is seeking a Principal Scientist in Translational Safety to provide scientific leadership across drug development, from early research through clinical and marketed products. You will lead safety assessments for multiple programs, integrating toxicology, pathology...
$141.5k - $262.9k
...challenges and transforming society.The OpportunityAs a Principal Scientist in Translational Medicine Oncology, you will serve as a vital scientific anchor... ...discovery research and clinical development. You will lead biomarker discovery and translational strategy for...PrincipalFull timeLocal areaRelocation package3 days per week$171k - $223k
...neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically...PrincipalLocal area$202.5k - $236.25k
...and collaborative individuals who are driven to make a positive impact. We are seeking a highly motivated and skilled Principal Scientist, Translational Genetics to join our growing team. The successful candidate will play a critical role in analyzing large-scale...Principal- ...patients suffering from diseases of cardiac muscle dysfunction. We are seeking a highly motivated computational scientist to lead translational biomarker discovery at the intersection of human genetics, multi-omics, and AI/ML. In this role, you will identify biomarkers...Principal
$190.8k - $300.3k
...seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific... ...Diseases/Vaccines portfolios. This role will lead the design, execution, analysis, and communication of translational and clinical biomarker strategies across programs...PrincipalLocal areaRelocationVisa sponsorshipFlexible hoursShift work$190.8k - $300.3k
...seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific... ...Oncology and Hematology portfolios. This role will lead the design, execution, analysis, and communication of translational and clinical biomarker strategies across...PrincipalFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$260.3k - $409.7k
...Leadership position in translational medicine focused on cardiovascular therapeutic development. Responsible for early clinical strategy... ...discovery and clinical research teams. Responsibilities Lead early clinical development strategy design and execution for novel...Principal- Gordian Biotechnology in South San Francisco is seeking a Principal Computational Biologist to shape how large-scale perturbation data... ...integrate multi-omics data, and collaborate with wet-lab groups to ensure rigorous, translatable #J-18808-Ljbffr gordian-biotechnologyPrincipal
$260.3k - $409.7k
...Merck seeks a physician-scientist to lead translational medicine and early clinical development for infectious disease therapeutics. The role bridges discovery research and clinical trials, requiring expertise in target validation, biomarker strategy, and clinical pharmacology...Principal- ...Principal Computational Biologist Are you ready to own the strategy behind how Gordian turns large-scale in vivo perturbation screens into a prioritized, translatable pipeline of therapeutic targets across chronic and age-related disease, and to help build sophisticated...PrincipalDay shift
- ...in South San Francisco, seeks a Senior Principal Research Scientist in Computational Chemistry... ...small molecule discovery. You will lead design efforts, partner with medicinal chemists... ...within a multidisciplinary team to translate computational insights into tangible #J...Principal
$202.5k - $236.25k
...Cytokinetics seeks a computational scientist to lead translational biomarker discovery in cardiac and skeletal muscle disease using human genetics, multi-omics, and AI/ML methods. The role bridges discovery research with clinical applications to identify disease biomarkers...Principal$268k - $384k
...yourself and report honestly when a contribution adds nothing. Co-design with ML scientists, mechanism scientists and engineers, translate model output into decisions people actually make, and publish — what is and is not predictable from mechanistic and human evidence...PrincipalFull timeWork at officeLocal areaFlexible hours$165.2k - $306k
...to announce an opportunity for a Senior Principal Scientist, Lab Head, to join the Synthetic... ...therapy programs. The position will lead a research group focused on developing next... ...novel programs in Synthetic Immunity. Translational Impact: Generate high-quality, original...PrincipalLocal areaRelocation package- A leading biotechnology company in South San Francisco is seeking a Senior or Principal Machine Learning Scientist. In this role, you will lead the development of large language... ...work on designing scalable systems and translating complex biological knowledge into...Principal
$173.1k - $321.5k
...the people we love.The Senior Principal Scientist serves as the... ...Bioanalytical Sciences, Research, Translational Medicine, Clinical Development... ...to efficacy, durability, and safety.Working collaboratively... ...Bioanalytical Sciences project leads to developing integrated bioanalytical...PrincipalFull timeLocal areaRelocation package- ...Responsibilities Role Overview We're hiring a Robotics Safety & Compliance Lead to own safety, risk, and compliance across our robotics operations... ...of risk assessment and incident management ~ Ability to translate standards into practical, operational processes ~ Clear...
$141.5k - $262.9k
...Toxicology group within the Translational Safety department is dedicated to... ...safety assessments, guide lead optimization, and de-convolute... ....Partner with Project Team Toxicologists, Discovery Scientists, and... ...or CRO environments.Senior Principal Scientist: Ph.D. with >5+...PrincipalFull timeLocal areaRelocation package- Genentech in South San Francisco, CA, invites a Principal Scientist in Structural Biology to lead cross-functional efforts integrating cryoEM, X-ray crystallography... ...will guide discovery teams, design constructs, and translate insights into drug discovery strategies. The role...Principal
$207.48k - $385.32k
...Analytical Data Science is recognized as a leading hub for top industry talent, operating... ...development.The OpportunityThe Senior Principal DSX Data Scientist in the Data Science Acceleration... ...clinical scientists, the Data Scientist translates scientific and operational needs into...PrincipalFull timeLocal areaShift work- ...in South San Francisco, CA, invites applications for a Principal Scientist, Lab Head, to lead a research group focused on designing next-generation... ...proteomics, tissue genomics, drug development, early clinical development and translational medicine. #J-18808-Ljbffr GenentechPrincipal
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