Manager, Applied AI, Advanced Informatics
$150.5k - $245.5kRegeneron Pharmaceuticals, Inc.
Role Description
The Manager, Applied AI is a research-facing technical role within the Advanced Informatics team responsible for designing and developing applied AI solutions across health data systems and analytical pipelines. This role works closely with senior applied AI leaders to:
- Formulate ML problems against complex health data
- Validate methods against clinical ground truth
- Build reusable analytical capabilities that the broader informatics team depends on
The ideal candidate brings solid grounding in AI/ML theory, hands-on experience applying it to real-world data problems, and is excited to deepen their expertise at the intersection of machine learning and health informatics.
This can be a remote position in the US or on-site position at our Tarrytown, NY, Armonk, NY or Warren, NJ offices.
Discover your role:
- Design and develop applied AI/ML solutions for health informatics use cases, from problem framing and data exploration through model development and evaluation.
- Translate business and clinical informatics challenges into well-scoped AI/ML problem statements with clear success criteria.
- Build and maintain ML pipelines including data ingestion, feature engineering, model training, and evaluation, in close collaboration with production engineering.
- Conduct experiments, benchmarking, and ablation studies to validate model performance and inform modeling decisions.
- Partner with clinical informaticists, data engineers, and production AI/ML engineers to integrate models into informatics workflows.
- Stay current with advances in foundation models, LLMs, retrieval-augmented generation, and their application to biomedical and health data domains.
- Contribute to research documentation, internal technical reports, and where appropriate, external publications or conference presentations.
- Communicate model behavior, limitations, and performance clearly to both technical and non-technical stakeholders.
Requirements
- Bachelor's degree (BS) in Computer Science, Machine Learning, Data Science, Biomedical Informatics, Statistics, or a closely related field required. Ph.D. or Master's degree strongly preferred given the research-facing nature of this role.
- 4–6 years of progressive experience in applied AI/ML, with demonstrated ability to independently develop and evaluate models. Ph.D. graduates with relevant research experience may be considered at the lower end of this range.
Knowledge, Skills & Abilities (Required)
- Solid understanding of supervised, unsupervised, and self-supervised learning; deep neural networks; and modern ML frameworks (PyTorch, TensorFlow, or equivalent).
- Strong command of Python and the scientific ML stack (scikit-learn, HuggingFace Transformers, pandas, NumPy, etc.).
- Experience designing and evaluating NLP or multimodal models, including fine-tuning or prompt engineering with large language models.
- Proficiency with experiment tracking, model versioning, and reproducible research practices (MLflow, W&B, DVC, or similar).
- Familiarity with cloud-based ML infrastructure (AWS SageMaker, GCP Vertex AI, Azure ML, or equivalent).
- Ability to drive technical work independently and communicate findings clearly across teams.
Knowledge, Skills & Abilities (Preferred)
- Experience with health or life sciences data — EHR/EMR records, claims data, clinical notes, genomic data, or imaging.
- Informatics domain knowledge (strong plus): familiarity with medical terminologies and ontologies (SNOMED CT, ICD-10/11, LOINC, RxNorm, OMOP CDM) and machinable health data standards.
- Published work or open-source contributions in applied ML, NLP, or computational biomedicine.
- Experience with MLOps pipelines, CI/CD for ML, and model observability in production environments.
- Familiarity with federated learning, privacy-preserving ML, or working with data use agreements in regulated environments.
Benefits
- Annual bonuses or other incentive plans
- Equity awards
- Pension or retirement benefits
- 401(k) company match
- Health and wellness programs
- Fitness centers
- Insurance benefits (e.g. medical, dental, vision, life and disability)
- Paid time off
- Family support benefits
Salary Range
$150,500.00 - $245,500.00
$176.6k - $294.3k
...Applied AI and Machine Learning Scientist (Director) ~ United States - Massachusetts - Cambridge... ...Research Unit (IMRU), translating advances in foundation models, agentic systems, multimodal... ...in day‑to‑day work. Shape and manage selected external partnerships relevant...SuggestedPermanent employmentH1bLocal areaVisa sponsorshipWork visaRelocation package2 days per week- ...media supply chain, data & analytics, IP & rights management, broadcast transformation, Salesforce and applied AI, our exceptionally talented teams partner with... ...matching and flexible vacation; we sponsor training to advance our teams' skill sets and we prioritize our...SuggestedInternshipWork at officeRemote workFlexible hours
$115k - $194k
Role Description As the Manager, IT SOX PMO, you'll own information... ...systems for SOX requirements, and advancing automation in a high-growth... ...technologies for SOX impact, and applying practical, scalable control... ...related to artificial intelligence (AI), and help prepare reports and...SuggestedFull timeFor contractorsWork at officeHome officeFlexible hours$184k - $287.5k
...validation data, resolve obstacles, apply workarounds, and detail... ...and finding solutions to deploy AI Factories globally. What you will be doing: ~Recruit & manage a team of solutions architects,... ...deep subject-matter expertise in advanced GPU and network systems and serve...SuggestedFull time$55 per hour
...engineering focus on leveraging advanced technologies and techniques to... ...Engineer... Full-time Safety Management System (SMS) Manager.... ...department... Remote Full-time AI data lab for training frontier... ...with disabilities, and others to apply. Equal Employment Opportunity...SuggestedHourly payFull timePart timeWork at officeLocal areaRemote workWork from homeNight shift$175k - $250k
...alignment with business goals AI and productivity... ...intelligence, automation, and advanced analytics to improve productivity... ...strengthens governance, risk management, business continuity, disaster... ...What You Should Know Before You Apply Interstates may collect personal...Work from home$220k - $385k
...customer-facing solutions, data and AI capabilities, and key... ...working by strengthening product management, optimizing vendor partnerships... ...North America. You’ll advance the application of data and AI... ...exactly who we’re looking for. Apply today and let’s go to great places...Temporary workWork at officeLocal areaWork from homeWorldwide$116.04k - $168.29k
...Description The Senior Delivery Manager is responsible for driving... ..., platform, analytics, AI/ML, and informatics leaders to plan, sequence,... ...role. ~Understands and applies current digital technology... ...Certified Scrum Master (CSM), Advanced Certified Scrum Master (ACSM...Full timeFlexible hours$115k - $160k
...and driver who will not just manage our IT operations, but strategically... ...that balance technological advancement with fiscal responsibility. 3.... ...strong sense of community. To Apply If you are a strategic IT... ...into each article, started with the help of AI. #J-18808-Ljbffr...Full timeRemote work- 10 - IT Project Manager 2 Req ID: 137500 Hiring Manager: Grace Rodriguez Santos Band... ...-outs, isolated lab network delivery, advanced AI platform provisions, and strategic... ..., state, and local laws. This policy applies to hiring, promotion, discharge, pay, fringe...Temporary workWork at officeLocal areaNight shift
$178.51k - $247.94k
...‑functional collaboration to advance enterprise performance and member... ...Intelligence, Analytics, and AI Enablement Architect and... ...personalization, lending strategy, risk management, and fraud prevention.... ...digital transformation, applying member‑centric design thinking...Full timeRemote work2 days per week1 day per week- ...(policy, digital education, AI, etc.) and address external threats... ...priorities. 30% IT Management Facilitate and manage information... ...initiatives to enhance the School's advanced technology. Partner with... ...technology innovation and applied research and development in large...Immediate startRemote workFlexible hoursNight shiftWeekend workEarly shift
- ...media supply chain, data & analytics, IP & rights management, broadcast transformation, Salesforce and applied AI, our exceptionally talented teams partner with... ...matching and flexible vacation; we sponsor training to advance our teams’ skill sets and we prioritize our...InternshipWork at officeRemote workFlexible hours
- ...media supply chain, data & analytics, IP & rights management, broadcast transformation, Salesforce and applied AI, our exceptionally talented teams partner with... ...matching and flexible vacation; we sponsor training to advance our teams’ skill sets and we prioritize our...InternshipWork at officeRemote workFlexible hours
$184.35k - $270.39k
...motivated and experienced Leader of ML and AI Engineering within the AI team. The... ...consumers, and team members. As a Senior Manager, MLE at Credit Acceptance, you will play... ...the organization. ~Explore and apply advanced machine learning techniques, including large...Full timeWork at officeLocal areaWork from home- ...leadership operating at the intersection of an advanced engineering technology director and a... ...business as a member of the senior IT management team, reporting directly to the CIO.... ...enablement and governance strategy for applied AI engineering initiatives, pioneering...Work at officeRemote workWorldwideShift work
$116k - $145k
...is seeking a Senior IT Project Manager to join our Shared Services... ...options and clear next steps. ~Apply PMBOK principles, governance... ...stakeholders at all levels. ~Advanced proficiency with Microsoft... ...initiatives. ~Experience leveraging AI-enabled tools, custom GPTs, or...Permanent employmentFull timeFor contractors$144k - $329.1k
...build a better working world. Role AI & Data - Data Architecture – Senior Manager – Power & Utilities Sector EY is... ...complex technical initiatives, you will apply your depth of expertise to guide... ...markets. Enabled by data, AI and advanced technology, EY teams help clients...Summer holidayFlexible hours- ...Care Coordinator - Care Management Mount Sinai Health Partners... ...the opportunity to thrive and advance professionally. Explore this... ...our time — discovering and applying new scientific learning and... ...artificial intelligence and informatics while keeping patients' medical...Full timeTemporary workTraineeshipLocal areaRemote workWork from homeShift work
$221k - $286k
...Job Description Senior Director, Applied AI, Design & Innovation Global Development... ...Design & Innovation is responsible for advancing the clinical trial experience through evidence... ...product development, and AI delivery management. Establish governance,...Full timeFor contractorsLocal areaRemote work$150k - $175k
..., and operationalizes modern AI capabilities (e.g., predictive... ...experience, and risk management. The ideal candidate is equally... ...fluent in business strategy and applied AI, with a track record of delivering... ...(Agile, product ops). ~Advanced degree in Business, Computer...Full timeShift work$110k - $180k
Position: Senior Technical Project Manager Location: Orlando HQ -... ...solution recommendations. Use AI-enabled tools and workflows... ...implementation practices. Advanced knowledge of Agile software development... ...US, the following conditions apply. If you are made a conditional...Full timeTemporary workWork at officeLocal areaRemote workFlexible hours$89.26k - $151.74k
...seeking an experienced Service Desk Manager to lead delivery of a modern, AI-enabled IT service desk supporting... ...reviews, and client stakeholders. Apply ITIL-based service management... ...candidates are instructed to contact us in advance at ****@*****.***....Full timeContract workWork experience placementWork at officeLocal areaRemote work$30 per hour
...and forward-thinking organization, apply now. We are currently seeking a... ...and financial services. Leveraging advanced technologies such as agentic AI, we enable organizations to adopt proactive... ..., and C-suite relationship management. Responsibilities: Serve as...Full timeTemporary workRemote workFlexible hours$107.1k - $199.8k
Role Description We are looking for a Senior Advanced Analytics & Insights Manager with 5+ years of experience to support high-impact analytics work across... ...who can work directly with complex healthcare datasets, apply data science methods, write strong SQL and Python, and...Full timeFlexible hours- ...The AI orchestration of your wildest imagination. n8n is... ...what you can build. If you’re applying, try n8n out - whether you’re... ...contributor role, you won't be managing a traditional 1:1 book of business... ...host live office hours, build advanced workflow templates, and step...Contract workTemporary workWork at officeLocal areaRemote workVisa sponsorship
$118.7k - $280k
Role Description In this role, you advance that mission by planning and directing the AI development that turns massive... ...with R&D Leadership, Product Management, and the Security Services (S2)... ...people. ~Sets the direction for applying the right approach to each problem...Full time- ...Description Baptist Health is looking for an AI Manager to join our team! This will be a... ...on, operational leadership role in advancing the organization’s applied artificial intelligence strategy... ...stakeholders ~IT ~Informatics ~Legal ~Risk ~External AI...Full timeRemote work
- ...Description Shape EPAM's frontier AI ecosystem and accelerate our... ...partnerships. As a Senior Manager of AI Alliances, you develop and... ...creates enterprise value ~Advanced business development and relationship... ...responsible AI frameworks) apply to enterprise business ~...Full time
- ...Delivery Manager Opportunity We're looking for an experienced Delivery... ...participation with sufficient advance notice Coach the team on... ...sessions, and metrics analysis Use AI tools to improve personal... ...solving and analytical skills, applied to identifying and removing delivery...Full timeTemporary workWork at officeRemote workHome officeFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Manager, Applied AI, Advanced Informatics. Be the first to apply!












