Principal Scientist
Drug Hunter
Drug Hunter is a B2B scientific intelligence platform for biotech/pharma R&D scientists that empowers them to discover the medicines of the future. We serve most of the top global biotech & pharma companies including Dow 30 and S&P500 companies. We're a mission-driven, product-focused company backed by top-tier investors and trusted by the world's leading R&D organizations.
We are looking for a Principal Scientists to join the Drug Hunter team. Principal Scientist are the science team’s scientific authorities and leaders. They are able to be responsible and accountable for scientific projects and areas from end to end, defining scope, scientific requirements, and creating high-quality deliverables with minimal direction, while raising the capability of scientists around them. Externally, scientists credibly represent Drug Hunter’s scientific strengths to expert audiences without support..
Core Competencies:
Scientific Expertise
- Recognized internal authority in at least one scientific area or discipline, with credible working coverage of adjacent areas
- Able to enter unfamiliar scientific domains and produce expert-level insight within days and critically review works from adjacent fields
- Demonstrates strong scientific judgment and reasoning, independently making decisions on deliverable requirements, publishable scientific claims, and relevance
- Easily catches subtle scientific and technical errors and issues, and scientific judgment is trusted in their areas of authority without routine review
- Assigned work in areas of authority are completed in a timely manner with high quality and scientific accuracy, and ready for external release with minimal oversight, editing, or review
- Confidently delivers external presentations, talks, and fields expert questions from scientists and leaders in real time in areas of authority
Collaboration & Influence
- Operates as a scientific partner to other functions including product development, engineering, and commercial, actively shaping plans and roadmaps in addition to responding to requests
- Translates scientific judgment and insight into business decisions
- Influence extends beyond their own projects: colleagues across functions seek their input and their recommendations impact areas for which they are not primarily responsible
- Maintains an external scientific network and reputation that brings ideas, contributors, and opportunities to Drug Hunter
Leadership & Mentorship
- Actively develops earlier career scientists and contributors on scientific activities and judgment including through structured review, feedback, and example
- Measurably raises the quality bar of work that they touch
- Leads projects staffed with other scientists, setting direction, unblocking activities, and taking accountability for the team’s output in addition to their own
- May manage 1-2 direct reports and be responsible for hiring, development plans, feedback, performance assessment, and reports’ workload and growth
Adaptability & Ownership
- Able to take accountability for and ownership of a project area in addition to individual projects, defining scope and priorities, committing to outcomes, and delivering results without needing direction on “how”
- Able to replan their areas of responsibility themselves when priorities or rationale shift, surfacing trade-offs and proposing new plans rather than waiting
- Moves into new domains, formats, or programs routinely
- Able to take on novel responsibilities as needed to advance team and company objectives
Requirements
- Ph.D.degree in a relevant scientific area
- Excellent interpersonal and communication skills, with fluency in English
- Typically 6+ years of post-Ph.D./postdoctoral experience, ideally in relevant industry settings
Benefits
Drug Hunter provides industry-leading benefits, including the following:
- Competitive salary, variable compensation, and equity
- Broad range of medical, dental, vision, and life insurance plans for employees and their dependents, including generous coverage for a platinum PPO healthcare plan
- Short-term disability and long-term disability insurance
- Cancer and critical illness coverage
- Up to 12 weeks paid parental leave (after 1 yr tenure) and childcare FSA plan
- 401(k) + employer match (3-5%)
- Home office set up stipend for fully remote employees
- Learning and development support
- Generous and flexible vacation and leave policies
- ...Prellis Biologics, a Berkeley-based biotech, seeks a Principal Scientist for Therapeutic Antibody Characterization to lead analytical characterization of mAbs, bispecifics, and Fc-fusion proteins, guiding candidate selection and preclinical development. You will apply...Principal
- With us, you'll get to:Lead our Cancer Prevention Group in researching and developing novel preventive cancer vaccinesPlease apply if you have:A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccinesIn-depth knowledge of and ...Principal
$66k - $171.6k
...Organization (API-EM) that delivers a diverse portfolio of medicines essential to our patients around the world. The API EM Senior or Principal Scientist will join the Technical Services/Manufacturing Sciences (TS/MS) team who work within a dynamic external manufacturing...PrincipalFull timeContract workH1bVisa sponsorshipWork visaFlexible hoursShift workNight shiftWeekend work- ...MassachusettsCompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts. We are looking for someone who thinks carefully about...Principal
- Job Title: Senior Scientist / Principal Scientist - Biotransformation/Metabolite Identification.Location: Exton, PennsylvaniaFull-time Job Description: We are seeking a highly motivated and experienced Senior Scientist specializing in Biotransformation and Metabolite Identification...Principal
$137k - $215.27k
...information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:The Pharmacovigilance Scientist, Senior Scientist ensures regulatory compliance and safety of Takeda's products by managing large projects, developing innovative...PrincipalMinimum wageLocal area- Qorvo (Nasdaq: QRVO) supplies innovative semiconductor solutions that make a better world possible. We combine product and technology leadership, systems-level expertise and global manufacturing scale to quickly solve our customers' most complex technical challenges. Qorvo...PrincipalWork experience placement
- Senior Principal Quality ScientistTwin Cities, MN (Hybrid)About the OpportunityWe are seeking an experienced Senior Principal Quality Scientist to provide quality leadership and oversight for research and development activities supporting regulated healthcare products....Principal
$137k - $235.75k
...and pioneering the path from lab to life while championing patients every step of the way.Learn more at Purpose: The Senior Principal Scientist will be a key member of discovery project teams and interact closely with biology, chemistry, and other drug metabolism and pharmacokinetic...PrincipalFull timeLocal area- Scientist/ Senior Scientist/ Principal Scientist, method Developer, Large Molecules Quantitation by LC-MS/MS, Bioanalytical ServicesLocation: Exton, PA (Corporate)Full timeResponsibilities:Mainly responsible for developing bioanalytical quantitation methods for large molecules...PrincipalTemporary workWork experience placement
$160k - $235k
...Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Boston, MA Salary Band: $160,000-$235,000 Location: Downtown Boston, MA Position Summary Antares Therapeutics is seeking to add an enthusiastic and highly motivated...Principal$173.1k - $321.5k
The PositionWe advance science so that we all have more time with the people we love.The Senior Principal Scientist serves as the scientific leader for Bioanalytical Strategy in support of our Cell Therapy portfolio. In this role, the individual will define and drive the...PrincipalFull timeLocal areaRelocation package- ...Leading scientific projects as a remote full-time Principal Scientist, the successful candidate will be responsible for defining project scope, delivering high-quality scientific insights, and mentoring junior scientists while representing the company's scientific strengths...PrincipalFull timeRemote work
$143.29k - $266.11k
The PositionThis role is a vital part of our Cell Therapy Process Development team within Pharma Technical Cell and Gene Therapy Development (PTCC), which is committed to advancing next-generation cell therapies through innovative metabolomics research and media optimization...PrincipalFull timeLocal areaRelocation package$137k - $235.75k
...more at Real-world Evidence & Advanced Analytics team within Johnson and Johnson Innovative Medicines is looking for outstanding scientists and leaders whose responsibilities include:Be a hands-on scientific and technical leader, leading a portfolio of RWE projects,...PrincipalFull timeLocal areaImmediate start- ...building needs a roof and at Carlisle Construction Materials (CCM), we make one the industry trusts. We are looking for a Principal TPO Scientist to serve as one of our foremost technical visionaries, who will define what the next generation of commercial roofing membrane...Principal
- ...Leading method transfer, validation, and routine testing, the full-time Principal Scientist, QC Analytical in Cell Therapy will serve as a subject matter expert in bioanalytical techniques while managing complex projects and representing the department in regulatory inspections...PrincipalFull timeRemote work
$115k - $215k
...quantitative proteomics data analysis tools.Domain leadership with cross-functional drug discovery:Highly organized, solutions-oriented scientist with the ability to manage multiple priorities simultaneously while driving innovation in targeted proteomics workflows and...Principal$144.9k - $269.1k
...power of data and Artificial Intelligence (AI) to assist our scientists in delivering more innovative and transformative medicines for... ...postdoctoral research or 3 years equivalent experience after PhD (Principal Scientist). The ideal candidate will have deep experience in...PrincipalFull timeLocal areaWorldwideRelocation package3 days per week$177k - $235k
...inspiring and exciting place to catalyze and enable medical breakthroughs. Position Description:We are seeking an innovative Principal Scientist to bridge the gap between traditional antibody discovery and cutting-edge computational design. In this role, you will serve...Principal$155.9k - $190.22k
...also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.Position OverviewThe Senior / Principal Scientist, Formulation and Drug Product Development will lead formulation and drug product (DP) development activities for Immunome's ADC...Principal- In vitro ADME Senior/Principal Scientist - DMPKLocation: Exton, PA Department: DMPK (Drug Metabolism & Pharmacokinetics)Employment Type: Full-TimeCompanyFrontage Laboratories Inc. is an award winning, publicly listed, full-service CRO/Contract Research Organization operating...PrincipalContract workTemporary work
$147.8k - $274.4k
...power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative... ...are seeking a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology group...PrincipalFull timeLocal areaWorldwide$120k - $150k
...Principal Scientist Title of Role: Principal Scientist Location: -, onsite Company Stage of Funding: Series B Office Type: Onsite Salary: $120K-$150K Company Description We're representing a dynamic company in the consumer healthcare and life...PrincipalWork at officeRemote work- ...development of safe and effective vaccines for the global swine industry. We are recruiting a highly motivated veterinary clinical scientist to contribute to advancing strategies in swine vaccine development at Zoetis. This scientist will have a specific focus on...PrincipalFull timeLocal area
- Reference: 630468Posted: 2026-09-03Location: San Diego, CaliforniaCompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** ResponsibilitiesContribute to the design, development, and optimization of LNP formulations for mRNA delivery, including...Principal
- ..., we respect the diversity and dignity of our employees and recognize their merit.We are searching for the best talent for a Principal Scientist, In-vivo CAR-T Potency Method Development to be located in Malvern, PA. You will be responsible for:Leading in-vivo CAR-T potency...PrincipalFull timeLocal area
- ...Senior/Principal Scientist, MPN Biology, Translational Sciences Job summary: PharmaEssentia Innovation Research Center (PIRC) is seeking a highly motivated and experienced myeloproliferative neoplasm (MPN) biologist to join our Translational Sciences team as a Senior...PrincipalContract work
$124k - $174k
...our people to achieve common goals. Together, let's build a brighter, healthier future for all.We are seeking an enthusiastic Principal Scientist to lead a segment of our dynamic Handsoap Personal Care R&D team. You will own the end-to-end product development lifecycle...PrincipalHourly payLocal areaRelocation$154.4k - $242.55k
...information I submit in my employment application is true to the best of my knowledge.Job DescriptionJoin Takeda as a Senior/Principal Scientist, Cell Based-Potency Assay Development. As an expert professional within the organization, you develop innovative solutions to...PrincipalMinimum wageContract workTemporary workLocal area
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Scientist. Be the first to apply!
- scientist ii United States
- regulatory scientist United States
- fermentation scientist United States
- principal scientist United States
- graduate scientist United States
- manufacturing scientist United States
- analytical scientist United States
- senior research scientist United States
- genomics scientist United States
- support scientist United States

