Postdoctoral Associate

About The Research Foundation for SUNY at Binghamton : Binghamton University is a premier public R1 research institution in the State University of New York (SUNY) system that unites more than 130 broadly interdisciplinary educational programs with some of the most vibrant research in the nation. Our unique character - shaped by our mission, outstanding academics, facilities, and community life - promotes extraordinary student success, research, and service; Binghamton University is where our students, faculty and staff thrive Working at Binghamton University is about more than having a great job - it is about having the opportunity to flourish in an exciting, engaging environment. Our faculty and staff appreciate Binghamton's collegial and inclusive culture and its commitment to excellence, education, innovation and civic engagement. Our diverse campus community contributes to our success. Embedded within the University, The Research Foundation (RF) exists to serve SUNY and to capitalize on the scope, scale and diversity of SUNY as an engine of New York State's innovation economy. We are the largest comprehensive university-connected research foundation in the country. The RF is mission focused and serves Binghamton University by providing essential administrative services that enable faculty to focus their efforts on the education of students and the performance of life-changing research. As a private not-for-profit corporation, we support nearly $1 billion in SUNY research activity annually, providing sponsored programs administration and commercialization support services to SUNY faculty performing research in numerous disciplines. The RF offers a comprehensive benefits package that is a valuable part of our total compensation. Included in the benefits package are comprehensive health, dental, and vision insurance, dependent care and healthcare spending accounts, employer retirement contributions at 7% of earnings, retiree health benefits and more! The RF promotes employee work/life balance through generous paid leave offerings and wellness resources for employees and their families. Furthermore, our 10 Perks of Working at the RF provides an at-a-glance view of our top benefits that make us a great place to work. Employees receive support throughout their career with access to professional development opportunities across campus, college savings plans, access to public student loan forgiveness programs, a tuition waiver program, and much more! Job Description: Develop synthetic methods to prepare backbone-modified RNA and peptide nucleic acids (PNAs). This will be done using techniques of synthetic organic chemistry and by adopting and optimizing solid-phase peptide, PNA, and RNA synthesis methods; Synthesize small interfering RNAs with various backbone modifications using an automated RNA synthesizer and the monomeric units prepared in (1); Test the biophysical and biological properties and RNA interference activity of the synthetic RNA molecules prepared in (2). Other tasks may include (but are not limited to) testing the effects of various backbone modifications in CRISPR RNAs and/or testing the ability of triplex-forming PNAs to modulate the structure and function of non-coding regulatory RNAs. The project integrates synthetic organic chemistry, nucleic acid chemistry, biophysics, biochemistry, and RNA biology to study the activity of backbone-modified RNAs and triplex-forming PNAs in live cells. The project is interdisciplinary and involves collaborations with structural biochemists. The Postdoctoral Research Associate will also be responsible for supporting these collaborative efforts. Requirements: Ph.D. in chemistry, biochemistry or related field. Experience with nucleic acid or peptide chemistry. Excellent problem-solving skills and the ability to work independently and in a collaborative research environment. Strong written and verbal communication skills. Preferred: Experience with molecular biology and cell culture techniques. Experience with RNA interference and CRISPR. Proven track record of publications in high-impact journals. Additional Information: Salary: $53,000 annually Employee Benefits: The Research Foundation for the State University of New York offers a comprehensive benefits package that is a valuable part of total compensation. This includes medical, dental, vision, dependent care subsidy and other benefits such as SUNY Tuition Assistance. Furthermore, our 10 Perks of Working at the RF provides an at-a-glance view of our top benefits that make us a great place to work. Research Foundation Commitment to Equal Employment Opportunity As an Equal Opportunity / Affi­rmative Action Employer, The Research Foundation for SUNY will not discriminate in its employment practices due to an applicant's race, color, creed, religion, sex, pregnancy‑related conditions, reproductive health decisions, childbirth or related medical conditions, sexual orientation, gender identity or expression, transgender status, age, national origin or ancestry, marital status, familial status, citizenship, physical and mental disability, prior arrest or conviction record, genetic characteristics/genetic information, pred­isposition or carrier status, domestic violence victim status, military status or service, veteran status, or any other characteristics protected under federal, state or local law. The Company will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. The Research Foundation for SUNY is a private, not for profit corporation and is a separate employer from SUNY and the State of New York and offers separate compensation and benefit plans. Binghamton University is a tobacco‑free campus.

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