Principal Scientist, Pathology

The Position We advance science so that we all have more time with the people we love. The successful Translational Safety Principal Pathologist candidate will provide scientific leadership and play an active role in the process of drug development from target assessment through marketed products. Working in a team environment, Translational Safety Project Pathologists participate in and may lead the strategic design, implementation, and data analysis of non-GLP investigative and GLP regulatory studies to ensure the comprehensive, highly integrated safety profiling of Genentech drug candidates. The Opportunity The responsibilities of this Principal Scientist project pathologist position will include: Provide veterinary clinical, technical, and scientific expertise on in-house and CRO-based studies from protocol development through necropsy, clinical pathology, and histopathology evaluations, pathology peer review and final report generation. Collaborate closely with toxicologists and study operations professionals, providing expertise in the development of streamlined, innovative safety assessment programs for Genentech drug candidates. Work independently to leverage literature to develop and optimize best‑evidence arguments in support of data interpretation or experimental approaches. Lead or coauthor high quality scientific manuscripts and regulatory documents, and represent Genentech/Roche in meetings with regulatory authorities to influence toxicologic pathology and industry standards in drug development. Collaborate with in vitro systems scientists to characterize and qualify assays for assessment of toxicity. Design and conduct in vitro and/or in vivo investigative and mechanistic studies in collaboration with toxicologists and subject matter experts. Advance applications of digital pathology for greater scientific insights and workflow efficiencies. Participate in the therapeutic area focused Expert Working Groups. Participate in and lead interdisciplinary project teams. Provide functional area mentorship and leadership in Pathology. Perform managerial, administrative, tactical, or strategic roles within Translational Safety, Development Sciences, or gRED, commensurate with experience. Who You Are A DVM/VMD, or equivalent, and board certification in the American College of Veterinary Pathology or European College of Veterinary Pathology. PhD in Integrative Pathobiology, or related discipline, preferred. Alternatively, a minimum of 5 years of relevant industry experience. Relocation Assistance benefits are not available for this posting. The expected salary range for this position based on the primary location of San Francisco, CA is $181,200 - $336,400 Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This position also qualifies for the benefits detailed here: Benefits. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. #J-18808-Ljbffr