Principal Scientist
Denali Therapeutics
Denali Therapeutics Inc in South San Francisco, CA, seeks a Principal Scientist to lead formulation and drug product development for a growing portfolio of protein biologics. You will design studies, establish shelf life, and support comparability across development stages. The role requires a PhD with 10+ years in DP/CMC for protein therapeutics, strong analytical skills, and hands-on LC-MS, HPLC, and cIEF experience. Collaboration with CMOs, QA, and other R&D teams is essential. #J-18808-Ljbffr Denali Therapeutics
$197k - $235k
...create an inspiring and exciting place to catalyze and enable medical breakthroughs.Position Description:Calico is seeking a Principal Scientist, Drug Metabolism and Pharmacokinetics to join our Drug Discovery team. This position is a unique opportunity to shape the DMPK...Principal$143.2k - $265.9k
The PositionThe OpportunitySE7As a Principal Scientist in Small Molecule Biomarkers (Metabolomics & Lipidomics) within our Drug Metabolism and Pharmacokinetics (DMPK) team, you will play a key role in advancing safe and effective therapeutics for patients. Joining Genentech...PrincipalFull timeLocal areaRelocation package$141.5k - $262.9k
...creativity while boldly pursuing answers to the world’s most complex health challenges and transforming society.The OpportunityAs a Principal Scientist in Translational Medicine Oncology, you will serve as a vital scientific anchor bridging discovery research and clinical...PrincipalFull timeLocal areaRelocation package3 days per week$200k - $240k
...medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Principal Scientist, Potency, you will report to the Sr. Director, Head of Molecular and Potency Method Development. You will either lead or...PrincipalTemporary workWork at officeImmediate startWeekend work$168.6k - $313k
...s what makes us Genentech. The Opportunity We are seeking a highly motivated and experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative research and development team. This is a technical leadership position within our Peptide Therapeutics...PrincipalLocal areaRelocation package$143.2k - $265.9k
...The Position The Opportunity We are seeking a creative and highly motivated Principal Scientist, Medicinal Chemist to join our R&D team. This is a primarily lab-based, technical leadership position within the Peptide Therapeutics department. In this lab-based leadership...PrincipalLocal areaRelocation package$164k - $205k
...Principal Scientist, Protein Engineering South San Francisco, California, United States Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to...PrincipalFlexible hours$143.29k - $266.11k
The PositionThis role is a vital part of our Cell Therapy Process Development team within Pharma Technical Cell and Gene Therapy Development (PTCC), which is committed to advancing next-generation cell therapies through innovative metabolomics research and media optimization...PrincipalFull timeLocal areaRelocation package$140k - $210k
...Senior Scientist/Principal Scientist, Protein Sciences: Analytical & Biophysical Characterizations Department: Technology/Protein Sciences Work Location: On-site role at our Corporate Headquarters (South San Francisco) Position Summary: Soleil is seeking an...PrincipalFull timeTemporary workFlexible hours- ...disease-relevant, translatable therapeutics in this space. As a Principal Computational Biologist, you go beyond executing individual... ...pathophysiology and experimental design with disease-area and experimental scientists as you are discussing computational models and analytical...PrincipalAgency workRemote workDay shift3 days per week
$194.1k - $305.6k
...Job Description The South San Francisco DMPK organization is seeking an accomplished and highly collaborative Senior Principal Scientist to provide scientific leadership across drug conjugate discovery and development programs, support strategic portfolio decisions,...PrincipalFull timeContract workFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$143.2k - $265.9k
The Position THE OPPORTUNITY The Department of Immunology Discovery at Genentech is excited to announce an opportunity for a Principal Scientist, Lab Head, to lead a research group focused on designing next-generation cell therapies to treat autoimmune diseases. The successful...PrincipalLocal areaRelocation package$176.2k - $277.3k
...purpose of turning breakthrough science into life-changing medicines. We are seeking an exceptional and experienced scientist in the role of Principal Scientist in the South San Francisco Discovery Biologics group. The qualified candidate will be a scientist with a...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$176.2k - $277.3k
...field, DVM, MD degree or equivalent. Minimum 8 + years of demonstrated pharmaceutical industry experience as a non-clinical safety scientist (e.g. Toxicology, Pathology etc.) and/or as non-clinical safety assessment representative to a cross-functional development and/or...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$141.5k - $262.9k
...challenges and transforming society. The Opportunity Genentech’s Department of Antibody Engineering is seeking a visionary Principal Scientist to lead a high-impact laboratory team at the forefront of biotherapeutic innovation. In this role, you will pioneer...PrincipalFull timeWork at officeLocal areaRelocation package- ...Warner Bros. Discovery is seeking a Principal Research Scientist (Recommender Systems) to lead large ML projects, advance personalization and search, and guide ML/AI researchers toward scalable solutions for HBO Max. The role partners with product, engineering, content...Principal
$260.3k - $409.7k
...Job Description We have an exciting opportunity for a physician-scientist to join our group as a- Principal Scientist (Clinical Director) in Translational Medicine/Early Clinical Development in the Infectious Diseases Therapeutic Area . Translational Medicine at...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$195.67k - $253.22k
...populations. The successful candidate will advance established as well as new programs, evaluate emerging antiviral concepts, mentor scientists, and remain directly involved in experimental design, assay execution, data interpretation, and troubleshooting. This position...PrincipalFull timeFor contractorsLocal area$176.2k - $277.3k
...DVM, MD degree or equivalent. - ~ Minimum 8 + years of demonstrated pharmaceutical industry experience as a non-clinical safety scientist (e.g. Toxicology, Pathology etc.) and/or as non-clinical safety assessment representative to a cross-functional development and/or...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$150k - $200k
...Job Description Principal Scientist – Histopathology & Translational Biomarkers \n \n Location : Bay Area, CA \n Compensation: $150,000–$200,000 annually \n Employment: Full-Time, Permanent \n \n We are seeking an experienced Principal Scientist to...PrincipalPermanent employmentFull time$185k - $215k
...range $185,000.00/yr - $215,000.00/yr * Posting for our client, Isotovia Biosciences * We are looking for an outstanding Principal Scientist to join our Discovery team at Isotovia Biosciences, a new company in San Carlos. This individual will be a part of an integrated...PrincipalFull time- ...responsible for CMC analytical development of AbbVie's pipeline of innovative therapeutic biologic products. We are a world-class team of scientists and leaders united by a shared mission to advance industry-leading analytical capabilities and meaningfully contribute to the...PrincipalFull timeLocal area
$155k - $260k
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value...PrincipalH1bVisa sponsorshipNight shift$190.8k - $300.3k
...Job Description We are seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific biomarker leadership across programs within the Cardiovascular & Metabolic and Infectious Diseases/Vaccines portfolios. This role will lead...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$159.6k - $251.2k
...Job Description We are recruiting an Associate Principal Scientist to join our In Vivo Pharmacology team located at our South San Francisco research laboratories. This role will focus on developing in vivo pharmacology strategy and pharmacodynamics (PD) and efficacy...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$260.3k - $409.7k
...all therapeutic areas within our Research Division with the role focused on Cardiovascular Disease and related conditions. The Principal Scientist (Clinical Director) must have a strong background in basic and/or clinical translational research and a desire to work...PrincipalFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$120.7k - $224.1k
The PositionWe advance science so that we all have more time with the people we love.This opening is for a Senior Scientist position in the translational Pharmacokinetics and Pharmacodynamics (tPKPD) department within the Development Sciences division in Genentech Research...Full timeLocal areaRelocation package- ...Brisbane, CaliforniaCompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** Research Associate - Scientist I, Discovery Biology The OpportunityPlan, execute, and analyze in vitro cell-based assays to support small molecule and degrader-...
- ...is to find better drugs, faster — and bring them to more patients who need them. Your role As a Senior Machine Learning Scientist , you will play a leading role in designing the next generation of foundation models of gene regulatory networks powered by Tahoe...Work at officeRelocation
- Client is seeking an experienced and driven scientist/engineer to lead late-stage upstream cell culture process development activities for clinical and commercial-stage large molecule programs. This individual will serve as the upstream lead for scale-up and tech transfer...PrincipalContract work
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