Overnight Clinical Research Nurse/Paramedic

Job Description

Job Description

Job Title: Clinical Research Nurse / Paramedic – Overnight Shift
Job Description

This role provides advanced clinical care and oversight for healthy volunteers participating in clinical research studies in a converted hospital research unit. You will perform complex nursing and paramedic activities, ensure accurate execution of study protocols, and prioritize the safety and welfare of all study participants. The position primarily operates on an overnight schedule and requires strong clinical judgment, attention to detail, and a calm, professional presence on a busy research floor.

Responsibilities

• Perform advanced nursing and paramedic activities in support of clinical trials, including informed consent documentation, medical history collection, adverse event and concomitant medication documentation, drug administration and accountability, dose verification, focused physical assessments, IV placement, IV infusions, vital signs, ECG lead placement, and other protocol-specific procedures.
• Conduct the practical, hands-on activities of clinical studies in strict accordance with study protocols, regulatory requirements, standard operating procedures (SOPs), scope of practice, and current training status.
• Stay current with SOPs, ICH/GCP guidelines, NIH guidelines, and applicable state and national regulatory requirements, and apply this knowledge consistently in daily practice.
• Maintain a calm, professional atmosphere on the study floors, leading by example in resolving conflicts professionally and delegating tasks appropriately.
• Ensure that the Study Manager and Clinical Floor Supervisors receive timely updates on study-related issues arising on the study floors, escalating urgent matters promptly and communicating other issues to the appropriate departments as warranted.
• Record participants’ adverse events accurately, including proper documentation and treatment as warranted, and escalate concerns to medical personnel or project management as appropriate.
• Administer oral study drugs while strictly ensuring the Five Rights of Medication Administration: the right subject, the right drug, the right dose, the right route, and the right time.
• Perform dose verification and assist other staff during dosing to accurately verify subject identity and dosing labels, providing an additional quality check.
• Contribute to and remain accountable for the secure and appropriate storage of all drug supplies after removal from the pharmacy, following all accountability procedures.
• Ensure all shift duties are completed according to the Charge Checklist or equivalent, including accurate completion of all applicable logs and metrics.
• Collaborate with colleagues across the unit to achieve departmental goals and support overall study success.
• Maintain awareness of organizational and departmental goals and help floor staff understand and engage with these goals to support their development.
• Maintain a clean, quiet, and orderly study environment in all study areas to support participant comfort and data integrity.
• Partner with the Training Department to perform and document process monitoring, ensuring staff compliance with procedures and adherence to training and regulatory standards.
• When required by study or site needs and when trained and delegated, perform additional study procedures such as obtaining participant information and histories, administering questionnaires, coordinating meals, collecting vital signs, performing EKGs, administering study drugs, collecting specimens, and conducting luggage searches.
• Work an overnight schedule of approximately 11:00 p.m. to 7:30 a.m., Monday through Friday, with the possibility of a Sunday through Thursday schedule subject to discussion with the hiring team.
• Provide coverage every other weekend when work is available, including locking up the unit on weekends and holidays as needed.

• Active Registered Nurse (RN) or Paramedic licensure in the state of Wisconsin.
• Medical background with a clinical skill set appropriate for advanced clinical research responsibilities.
• Training or in-training status as a Clinical Research Technician – Advanced or Clinical Research Nurse – Advanced.
• Demonstrated professionalism, leadership, and problem-solving skills in a clinical floor environment.
• Approximately 6 months of effective performance as clinical floor staff in a similar setting or equivalent external experience in a charge, supervisory, or leadership role that can translate immediately to a charge-level role.
• Proficiency in clinical research activities including pre-screening participants, obtaining informed consent, following study protocols, and adhering to regulatory and ethical standards.
• Ability to accurately measure and document vital signs and perform ECG lead placement and ECG procedures.
• Competence in IV placement and IV infusions in a clinical research setting.
• Strong understanding of and adherence to ICH/GCP guidelines, NIH guidelines, SOPs, and relevant state and national regulations.
• Ability to administer medications safely, including strict adherence to the Five Rights of Medication Administration.
• Skill in documenting adverse events and concomitant medications accurately and escalating clinical concerns appropriately.
• Basic Life Support (BLS) certification obtained within 6 months of hire or promotion date.
• CPR certification obtained within one year of hire or promotion date.
• Willingness and ability to work an overnight schedule and provide coverage on alternating weekends.

• Previous experience in a clinical research environment, particularly in a charge or supervisory capacity, is highly beneficial.
• Experience working with healthy volunteers in a controlled inpatient or unit-based setting.
• Familiarity with regulatory documentation, including informed consent forms and study-specific logs and metrics.
• Advanced Cardiac Life Support (ACLS) certification, or willingness to obtain it within one year of hire or promotion date if required.
• Strong communication skills to interact effectively with study participants, colleagues, and cross-functional teams.
• Ability to maintain composure and exercise sound judgment in a 24-hour facility with shifting priorities.
• Comfort working with electronic systems, logs, and documentation tools commonly used in clinical research.

This role is based in a former hospital that has been converted into a dedicated clinical research unit in West Bend, Wisconsin. The facility spans three floors and can accommodate up to 200 beds, with typical operations currently around 50 participants, distributed across floors with approximately 20 to 30 healthy volunteers per floor. The environment is a 24-hour facility focused on clinical trials with normal healthy individuals, emphasizing participant safety, comfort, and protocol adherence. The unit operates primarily on an overnight schedule for this role, generally from 11:00 p.m. to 7:30 a.m., Monday through Friday, with the possibility of a Sunday through Thursday schedule subject to discussion. Training consists of two weeks on first shift to ensure thorough onboarding; alternative training arrangements may be considered when necessary. Staff are expected to be available every other weekend when work is present and to assist with securing and locking the unit on weekends and holidays as needed. The facility offers an on-site chef who prepares meals for both participants and employees, with staff able to purchase meals at a low cost, creating a convenient and supportive work environment. The study floors are maintained as clean, quiet, and orderly spaces to support high-quality data collection and participant well-being, and staff work closely with medical, project management, and training teams while using standard clinical equipment such as IV supplies, ECG machines, and vital sign monitors.

Job Type & Location

This is a Permanent position based out of West Bend, WI.

The pay range for this position is $72800.00 - $93600.00/yr.

Benefits. Benefits. Benefits. Benefits. Benefits. Benefits. =Benefits. Benefits.

This is a fully onsite position in West Bend,WI.

This position is anticipated to close on Jun 11, 2026.

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