Associate Director

The Associate Director of Cell Line Development at BIB will lead a team of scientists and associates to develop mammalian cell lines and strains for the expression of therapeutic proteins. As a core member of the Biopharmaceutical Development management team, the director will be responsible for the strategic planning and growth of cell line and strain development functions. Responsibilities Lead the development and optimization of mammalian cell lines and microbial strains to produce therapeutic proteins. Lead the activities range from vector development, screening, transfections, media optimization, development of stable cell lines and cell banking activities. Manage team to perform recombinant protein characterization activities including ELISA, PCR, SDS-PAGE, western blot, etc. Direct cell line and strain development innovation projects, new technology evaluation/ implementation, as well as conference presentation and journal publication. Contribute to department and corporate strategic planning and objectives setting. Mentor team members and manage department budget. Provide technical support to business and sales team and represent cell-line development functions in client meeting. Author SOPs, protocols and technical reports and ensure adherence to high technical standards and compliance with applicable regulatory guidelines. Maintain accurate experimental records and results in laboratory notebook and/or datasheet. Qualifications B.S., M.S. or Ph.D. in Molecular Biology or related discipline. Ph.D. with ≥11 years, M.S. with ≥14 years, or B.S. with ≥16 years industry experience. Demonstrated Scientific and Engineering expertise developing mammalian cell line optimization and mammalian expression technologies for the generation of monoclonal antibody and recombinant protein therapeutic products. Expertise working with a variety of microbial strains, cell lines and mammalian expression systems especially CHO, HEK and NS0, prior experience with CHO-GS system is highly desired. Experience with bi-specific cell line development is highly preferred. Able to analyze complex molecular biology problems, develop strategic initiatives and execute technical programs, and make recommendations to executive management. Ability to work in a fast pace environment, manage priorities, and maintain timelines for multiple projects is required. Strong knowledge in PAT technologies, GMP / ICH guidelines and CMC experience. Advanced cross-functional communication, written and presentation skills. Effective organizational and staff management skills. Proficient in statistical design of experiment and data analysis using JMP, Minitab, or Design Expert software. Flexible and results oriented. Salary Range: $150,000-$160,000 annually BIB is a full service CDMO partner offering cGMP and non-GMP mammalian, microbial, gene therapy and cell therapy services. #J-18808-Ljbffr