Senior Director, Clinical Development
$274.4k - $411.6kTango Therapeutics
Company OverviewTango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.Summary The Senior Director, Clinical Development will provide medical and scientific leadership for Tango’s oncology development programs, driving clinical strategy from early-stage development through registration. Reporting to the President, Research & Development, this individual will lead cross-functional clinical teams, shape development plans, oversee study execution and medical monitoring, and serve as a key partner to investigators, regulators, and senior leadership. This highly visible role combines strategic leadership with hands-on clinical development responsibilities and offers the opportunity to directly influence the advancement of innovative precision oncology therapies for patients. The Senior Director will build and maintain strong relationships with investigators, key opinion leaders (KOLs), and external partners while ensuring the successful execution of clinical studies and overall program objectives. Your Role: Lead the clinical development strategy and execution for assigned clinical-stage oncology asset(s), partnering with cross-functional teams to create and implement comprehensive clinical development plansProvide leadership to the clinical team and serve as the medical and scientific expert for development programsDesign, author, and oversee the development of study protocols, protocol amendments, investigator brochures, and other key clinical documents in compliance with project plans, global regulations, ICH/GCP guidelines, and Good Medical PracticeServe as the primary clinical lead for study investigators and key opinion leaders, building strong relationships that support program success and scientific advancementLead clinical contributions to regulatory submissions, including INDs, CTAs, NDA/MAA filings, and interactions with Health AuthoritiesAct as Medical Monitor and/or oversee external Medical Monitors for company-sponsored clinical trials, ensuring appropriate medical oversight and patient safetyProvide strategic oversight of adverse event review, safety monitoring, protocol compliance, and clinical data evaluationPartner closely with Clinical Operations, Clinical Pharmacology, Biometrics, Regulatory Affairs, Drug Safety, Data Management, Quality, and Translational Sciences to ensure integrated and efficient execution of development programsAnalyze and interpret clinical trial data and communicate findings through regulatory submissions, scientific publications, medical congress presentations, and internal governance reviewsLead responses to questions from Health Authorities, Ethics Committees, and Institutional Review Boards, ensuring consistency and scientific rigorContribute to portfolio strategy, development planning, and broader organizational initiatives as neededPerform additional responsibilities as required to support the advancement of Tango’s clinical programsWhat You Bring: MD required; board certification or board eligibility in Medical Oncology, Hematology/Oncology, or a related specialty strongly preferred5+ years of clinical development experience within the biotechnology and/or pharmaceutical industry, including experience leading oncology development programsDemonstrated experience in the design, execution, interpretation, and reporting of oncology clinical trials involving targeted therapies, small molecules, and/or immuno-oncology agentsExperience supporting or leading late-stage clinical development programs, NDA/BLA/MAA submissions, and Health Authority interactionsStrong understanding of the biological and translational sciences underlying modern oncology drug development, including molecular biology, cancer genetics, immunology, and precision medicine approachesProven ability to lead and influence cross-functional teams within a matrixed organizationExcellent strategic thinking, organizational, and project leadership skills, with the ability to balance high-level planning and hands-on executionStrong problem-solving skills and the ability to identify innovative approaches to advance development programs and organizational objectivesExceptional communication and presentation skills, including the ability to engage effectively with senior leadership, investigators, KOLs, and regulatory agenciesDemonstrated leadership capabilities with a collaborative, team-oriented, and results-driven approachFlexible, resourceful, and entrepreneurial mindset with the ability to thrive in a dynamic and fast-paced biotechnology environment #LI-HybridWe are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.Salary range $274,400—$411,600 USD
$274.4k - $411.6k
...Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.Summary The Senior Director, Clinical Development will provide medical and scientific leadership for Tango’s oncology development programs, driving clinical strategy...Senior- ...This is what you will do:The Senior Medical Director, Clinical Development may lead the clinical sub-team or support the clinical sub-team and the global program team to build global clinical development plans and contributes to the development of asset level and therapeutic...SeniorHourly payFull timeTemporary workWork at office
$292k - $409k
...class potential in small cell lung cancer, now in clinical trials. At the same time, our R&D team is... ...long-term growth. Job Description The Senior Medical Director will lead late-stage clinical development programs in Oncology, including pivotal Phase III...SeniorFull timeWork at officeWorldwideRelocation package$210.9k - $379.2k
The Role:Moderna is seeking an experienced oncology drug developer lead Clinical Development for one or more mRNA-based precision immunotherapies. Experience is early-phase development is essential. This role will report to the Head of Early Clinical Development, Oncology...SeniorPermanent employmentFull timeWork at officeWork from home- ...Senior Medical Director, Clinical Development (Medical Monitoring) About the Company Rapidly growing organization in the oncology & hematology industry Industry Hospital & Health Care Type Privately Held About the Role The Company is seeking a Senior...Senior
$215k - $335k
...Pioneering Medicines, Flagship Pioneering’s in-house drug development unit, is dedicated to conceiving and developing a... ..., development, and production.Position Summary:The Clinical Development Lead (Medical Director or Senior Medical Director level) is a Physician-Scientist...SeniorRemote work$280.6k - $420.8k
...Job DescriptionGeneral Summary:The Senior Medical Director will define the clinical development strategy of povetacicept in primary membranous nephropathy, work with cross-functional multidisciplinary teams to define overall asset strategy as well as clinical trials strategy...SeniorFull timeSummer workRemote workFlexible hours2 days per week$282.2k
Job DescriptionThe Senior Director (Sr. Principal Scientist) has primary responsibility for the planning and directing clinical research activities involving new or marketed medicines... ...medicines span all phases of clinical development (pre-clinical to post-licensure). The...SeniorFull timeFor contractorsLocal areaFlexible hours$282.2k
...Job Description The Senior Director (Sr. Principal Scientist) has primary responsibility for the planning and directing clinical research activities involving new or marketed medicines... ...span all phases of clinical development (pre-clinical to post-licensure). The...SeniorFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- ...execution and interpretation of clinical trials or research activities of a clinical development program. Participates in cross-... ...Qualifications Medical Director Qualifications: Medical Doctor... ...English communication skills. Senior Medical Director Qualifications...SeniorLocal area
- ...direction, planning, execution, and interpretation of clinical trials or research activities of one or more clinical development programs. Participates in cross-functional... ...documents. May oversee the work of Medical Directors and/or Scientific Directors, and of Clinical...SeniorLocal area
$203.21k - $304.82k
...outcomes, across discovery, translational science, biomarkers and clinical development. Role Overview AstraZeneca is building a world-class AI... ...that turn this ambition into delivered value. This is a senior, strategic portfolio-owner role. You will lead the strategy...SeniorFull timeTemporary workWork at officeFlexible hours3 days per week- ...Job Title: Global Development Senior Medical Director, Hematology Oncology Hybrid Working: In the office a minimum of 3 days per week Location... ..., Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated...SeniorHourly payTemporary workWork at officeLocal areaWorldwide3 days per week
$245k - $300k
...Job Description Job Description Description: Sr. Director/Vice President of Clinical Development At Merida Biosciences, we are pioneering true... ...hiring range for this role upfront: typically for the Senior Director level we target $245,000 to $300,000. The final...SeniorLocal area$284.25k
...biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.The Senior Medical Director, Oncology Clinical Development - Lung is a senior physician leader within the clinical programme team, providing medical oversight,...SeniorFull timeWork at officeLocal areaRelocation2 days per week- ...direction, planning, execution, and interpretation of clinical trials or research activities of one or more clinical development programs. Participates in cross-functional... ...documents. May oversee the work of Medical Directors and/or Scientific Directors, and of Clinical...SeniorFull timeLocal area
$284.25k
...timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.The Senior Medical Director, Oncology Clinical Development - Sarcoma, is a senior physician leader within the clinical programme team, providing medical oversight, strategic...SeniorFull timeWork at officeLocal areaRelocation2 days per week$284.25k
The Senior Medical Director, Oncology Clinical Development - GU will report to the Executive Medical Director, Clinical Development Lead (CDL), Oncology Clinical Development. The Sr. Medical Director will be responsible for clinical research activities pertaining to advancing...SeniorFull timeWork at officeLocal areaWorldwide2 days per week- ...We are conducting a confidential search for a Director of Clinical Development to lead clinical development programs within a leading biotechnology organization. This is a high-impact, director-level opportunity based in Boston on a hybrid model for a seasoned clinical...Full time
$272k - $302k
...disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation... ...from pre-clinical development into the clinic. The medical director will serve an integral role in the clinical development...Full timeTemporary work$220k - $240k
...evaluated in MIST, a global Phase 2b clinical trial in patients with... ...expertise in rare respiratory disease development, Avalyn aims to establish a new... ...LinkedIn. Position Summary: The Director, Clinical Development will report to the Senior Vice President, Clinical...Interim roleLocal area$155k - $165k
...demonstrated ability to bring in new revenue and drive significant growth. As a key member of the executive team, the Senior Director of Development will help set organization-wide strategy alongside senior leadership, build and execute a bold revenue strategy, expand...SeniorFull timeWork at officeLocal areaRemote workFlexible hours1 day per week$228.8k - $343.2k
...SummaryTango has an exciting opportunity to join the team as our Senior Director, Clinical Sciences. This is a hands-on leadership role that combines... ...with direct scientific leadership of one or more clinical development programs. The successful candidate will mentor and develop...Senior$332k - $423k
...About This Role As the Executive Medical Director for Clinical Development, marketed MS and NeuroPsychiatry, you will provide scientific and strategic leadership while overseeing asset-specific programs. You will manage 2-4 programs, focusing on key goals such as meeting...Full timeTemporary workLocal area$315.2k
...visionary and strategic oncology leader to serve as Executive Director, Clinical Development. Reporting directly to the President of Research &... ...clinical development strategy for an early-stage program.As a senior clinical and scientific leader, you will partner with Translational...$320k
...patients with immune-mediated diseases, Vertex is building the clinical organization to match its scientific ambition in... ...indications with compelling early signals. As Executive Medical Director, Clinical Development, you will serve as Vertex's primary physician voice on...Full timeSummer workRemote workFlexible hours2 days per week- ...Executive Director, Clinical Development About the Company Excelling biotechnology (BioTech) company Industry Biotechnology Type Privately Held Founded 2017 Employees 51-200 Categories Biotechnology B2B Health Care Medical Therapeutics...
$235.5k - $318.6k
...Summary of Key Responsibilities:Clinical pathology assessment of preclinical results for platform and program supportReview non-GLP... ...biomarker and translational expertise across Research and Early Development Participate in group, department and company meetings and activitiesQualifications...SeniorFull timeTemporary workLocal areaFlexible hours- ...Senior Director, Clinical Pharmacology Reporting to the SVP of Research, the Senior Director, Clinical Pharmacology will drive all aspects... ...toxicokinetic (TK) and pharmacodynamic (PD) assessments, biomarker development and biodistribution studies, and will be accountable for...SeniorWork at office3 days per week
$235k - $330k
Who we are:Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation... ..., seen, and heard.How you’ll make an impact:The Senior Director of Early Phase Formulation Development will provide scientific leadership for preformulation...Senior
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