Senior Manager, Commercialization FP&A

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi‑selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C‑selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D‑selective inhibitor; and RMC-5127, a RAS(ON) G12V‑selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity Revolution Medicines is seeking a Senior Manager, Commercialization FP&A to support our growing Global Commercialization organization. The Senior Manager, Commercialization FP&A will be a key operational finance partner across Global Commercial Development, US Commercialization, and Global Medical Affairs teams. This role reports to the Senior Director, Commercialization FP&A and is based out of our headquarters in Redwood City, CA. Responsibilities Support Global Commercialization FP&A cadences including annual budget, quarterly forecasting, and long‑range planning; partner with functional leaders to align assumptions, timing, and resource needs and utilize FP&A systems (Adaptive) for consolidation and reporting. Own and deliver executive‑ready management reporting packages (budget vs. actuals, forecast updates, regional/product P&L views as applicable) and clearly communicate key insights, risks, and opportunities. Drive monthly variance analysis of actuals vs. budget/forecast; investigate discrepancies, understand key business drivers, and provide actionable recommendations to stakeholders. Provide ad hoc analytical support to enable decision‑making, including spend tracking, benchmarking, and scenario analysis (e.g., resourcing trade‑offs, vendor strategy, and investment prioritization). Lead the monthly accounting close process for Global Commercialization OPEX, including preparation of month‑end OPEX accrual journal entries and review of open POs, invoices, and service completion status in coordination with Accounting/Procurement and functional operations teams. Establish and maintain governance for PO coding and mapping to ensure alignment to business initiatives, accurate initiative‑level reporting, and scalable cost management practices. Maintain a continuous improvement mindset across processes, systems, and reporting—identifying opportunities to standardize, automate, and strengthen controls as Revolution Medicines scales into a global, fully integrated commercial‑stage company. Required Skills, Experience and Education Bachelor’s degree in Finance, Accounting, or related field. 6+ years’ experience in a similar role in biotechnology industry. Highly proficient in Excel, PowerPoint and AI automation (Codex, Claude Code). Experience working effectively in a demanding environment with minimal direction. Strong work ethic and ability to adjust workload based on changing priorities. Highest standards of accuracy, precision, and diligence; highly organized. Ability to think creatively, highly driven, and initiative‑taking. Ability to work effectively and collaboratively cross‑functionally with demonstrated ability to multi‑task, prioritize options, anticipate challenges, and execute corporate goals. Strong analytical and advanced excel skills as well as excellent written and verbal communication skills. Preferred Skills CPA or MBA preferred. Demonstrated experience utilizing financial systems and other business intelligence tools; NetSuite, Adaptive Insights (including OfficeConnect), and Coupa experience. Base Pay Salary Range

$164,000 - $205,000 USD

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact View email address on click.appcast.io. We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to View email address on click.appcast.io so we can share these impersonations with our IT team for tracking and awareness. #J-18808-Ljbffr Revolution Medicines