Principal Scientist, Preclinical Safety & Translational Sciences-Translational Pharmacokinetics/Pharmacodynamics
$117k - $201.25kJohnson & Johnson
Principal Scientist role in preclinical safety and translational sciences focused on pharmacokinetics and pharmacodynamics modeling. The position supports drug discovery and early clinical development through quantitative model-based analyses to inform candidate selection and dosing strategies.
Responsibilities
- Apply PK/PD modeling to inform project decisions across discovery through early clinical studies
- Develop physiologically-based and mechanistic modeling approaches to predict drug profiles
- Quantify exposure-response relationships for biomarkers, efficacy, and safety outcomes
- Guide experimental designs to generate the most informative data for modeling and analysis
- Contribute to organization-wide modeling and simulation strategies
Requirements
- PhD in Pharmacology, Engineering, Mathematics, Physics, or related field with 4+ years industry experience; or Master's degree with 6+ years experience
- Strong knowledge of pharmacokinetic and pharmacodynamic principles with PK/PD modeling experience
- Demonstrated mathematical modeling and simulation skills with peer-reviewed publications
- Excellent written and oral communication abilities
- Strong interpersonal and teamwork skills
- Experience guiding experimental design for modeling applications
Compensation: $117,000-$201,250 base
Vacancy posted 2 days ago
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