Senior Director, Human Resources Business Partner, Global Commercial Strategy

Job DescriptionRole SummaryThe Senior Director, Human Resources Business Partner (HRBP) provides strategic HR partnership to leaders across Global Commercial Strategy, U.S. Pricing & Access / Government Affairs, Global Pricing, and Health Economics & Outcomes Research (HEOR).Reporting to the Head of HR for Commercialization, this role focuses on talent strategy, organizational design, and supporting commercial transformation efforts.This role partners closely with the VP of Commercial Transformation to align people and organizational priorities with the broader Commercial Transformation agenda, and in support of the resources within the transformation office.Key ResponsibilitiesHR Business PartnershipServe as a strategic HR advisor to senior leaders across multiple Commercialization functionsProvide guidance on organization design, talent management, and workforce planningSupport leaders in aligning people strategies to business prioritiesCommercial Transformation SupportPartner with Commercial Transformation leadership to support execution of transformation initiativesTranslate business priorities into organizational and talent implicationsSupport implementation of new operating models and ways of workingTalent StrategySupport identification and assessment of critical roles across CommercializationPartner with Talent and business leaders on succession planning and development strategiesContribute to capability-building and commercial excellence initiativesOrganizational Effectiveness & ChangeSupport organizational design and change initiatives across supported functionsProvide coaching and guidance to leaders during periods of changeUse data and insights to inform talent and organization decisionsHR Delivery ModelPartner with a shared People Advisor who supports employee relations, performance management processes, and day‑to‑day HR needsEnsure alignment between strategic priorities and HR program executionQualifications10–12+ years of HR experience, including HR Business Partner roles in complex, matrixed organizationsExperience supporting commercial, pricing, access, strategy, or value functions preferredExperience in organizational design, talent management, and change initiativesStrong business acumen and ability to influence senior stakeholdersPay Range:$227,200 - $340,800Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Flex Designation:Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select2. On-Site: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-HybridCompany InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io: Boston, MAType: Full time