Senior Associate Scientist - Engineered Cell Therapy Discovery

R1603327 : Senior Associate Scientist - Engineered Cell Therapy Discovery Company: BMS Req Number: R1603327 Location: Seattle-WA Position Summary We are seeking an innovative and driven Senior Associate Scientist to join the Engineered Cell Therapy Discovery team and help advance next-generation CAR T and eTCR therapies for patients with cancer and other chronic diseases. In this role, you will apply immunological knowledge and experimental rigor to design and execute detailed functional assays, support screening of engineered T cell constructs, and interpret large biological datasets that shape discovery decisions. You will work closely with scientists across disciplines to develop robust assay platforms, evaluate engineered cell function in relevant biological models, and communicate clear, data-driven recommendations. The ideal candidate is excited by the intersection of immune cell engineering, quantitative biology, and scalable data generation in a fast-paced discovery setting. Position Responsibilities Applies strong immunological knowledge to the design, execution, and interpretation of studies evaluating engineered T cell CAR/eTCR constructs, novel payloads/gene editing across diverse biological conditions. Contributes to screening strategies that assess engineered T cell constructs and functional responses leveraging automation where applicable, enabling data-driven prioritization of candidates. Performs fine-detailed, nuanced mechanistic studies to interrogate engineered T cell function using multiparametric immune profiling approaches, including assessment of activation, exhaustion, memory, and effector phenotypes. Analyzes and interprets complex datasets from cellular, molecular, and functional assays to identify biological trends, support hypothesis generation, guide experimental follow-up, and enabling data-driven prioritization of candidates. Develops and optimizes novel assays to quantitatively assess the biological and functional properties of novel synthetic biology in engineered T cells. Ensures the robustness and reproducibility of these assays to support key project milestones. Generates and cryopreserves CAR T cells and eTCR T cells with complex genetic engineering approaches. Performs phenotypic and functional analysis of CAR and eTCR T cells using flow cytometry, IncuCyte, MSD, and other relevant methods. Analyzes data to provide insights into the performance, quality, and potential of engineered T cells. Participates in troubleshooting activities related to the evolution of new approaches/technologies. Collaborates effectively with cross-functional teams. Communicates findings clearly and concisely to stakeholders at all levels. Maintains electronic notebooks in a rigorous and timely manner to support project milestones and patent/regulatory filings. Basic Qualifications Bachelor’s Degree 4+ years of academic and / or industry experience Or Master’s Degree 2+ years of academic and / or industry experience Preferred Qualifications Required developed knowledge of the principles and concepts of biological sciences, immunology, bioengineering, or related discipline. Experience developing and using quantitative in vitro assays to drive decision-making, especially in the drug development context, is strongly desired Experience with automation platforms, including liquid handling systems or related technologies, in a high-throughput screening context is strongly desired. Experience analyzing and visualizing complex biological datasets using software such as JMP, R, or similar quantitative analysis tools is preferred. Familiarity with data handling and analysis best practices for screening, multiparametric flow cytometry, or other higher-content assay platforms. Proficiency in MSD, IncuCyte-based assays, multi-parameter flow cytometry, and/or high-content imaging technologies is strongly desired. Skilled in generating, expanding, characterizing, and cryopreserving CAR T and eTCR T cells. Experience with antibody discovery and molecular biology is preferred. Excellent organizational skills for thorough and timely documentation of experiments across multiple projects. Maintains electronic notebooks rigorously. Ability to independently recognize potential problems and recommend/develop appropriate solutions strongly desired. Strong communication skills for working with cross-functional teams as well as cross-departmental colleagues. Ability to work productively as both team member and as individual contributor. Compensation Overview Seattle - WA: $102,570 - $124,290 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit Benefit Offerings Health Coverage: Medical, pharmacy, dental, and vision care. Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to View email address on click.appcast.io . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Candidate Rights BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at . Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law. #J-18808-Ljbffr Bristol Myers Squibb