Principal Investigator

Principal Investigator (Part Time)

As a Principal Investigator, you will lead and oversee clinical investigation protocols, ensuring adherence to FDA regulations and GCP/ICH guidelines. You will manage the medical care of research subjects, protect their rights and welfare, and ensure the validity and documentation of trial data.

Responsibilities:

• Complete required training, including GCP and IATA.
• Maintain a working knowledge of FDA regulations, GCP/ICH guidelines, SOPs, and study protocols.
• Keep an up-to-date curriculum vitae and current licensure to practice.
• Assume responsibility for clinical investigation protocols.
• Understand the requirements of each protocol thoroughly.
• Determine adequate resources for conducting research protocols.
• Manage the medical care of subjects and protect their rights and welfare.
• Ensure validity of trial data reported to sponsors.
• Document study-related procedures, processes, and events.
• Ensure proper use and storage of Investigational Products.
• Attend investigator meetings as necessary.
• Assist with creating PI oversight plans for studies.
• Conduct and oversee staff training.
• Conduct patient consent discussions, ensuring understanding of procedures, risks, benefits, and alternatives.
• Provide clear explanations of study protocols and ensure patient understanding before obtaining consent.
• Facilitate effective communication between patients, healthcare providers, and research staff.

Essential Skills:

• Clinical research expertise.
• Minimum of 1 year of clinical research experience - preferably within general medicine or other complex therapeutic area.
• Experience with Phase I clinical trials.
• Medical Doctor (M.D.) or Doctor of Osteopathy (D.O.) with an active medical license.
• Compliance with clinical trial regulations.

Additional Skills & Qualifications:

• Board certification or eligibility in a relevant specialty.
• Training and certification in SOPs, and Good Clinical Practice (GCP).

Work Environment:

This position requires onsite work, ensuring direct engagement with research activities and protocols.

Job Type & Location:

This is a Permanent position based out of Houston, TX.

Pay and Benefits:

The pay range for this position is $270400.00 - $312000.00/yr. Texas's largest private research network, teams up with dedicated doctors, researchers, medical and scientific leaders to shape the future of medical advancements. Offers competitive pay and benefits, and rewards high performance with excellent career opportunities.

Workplace Type:

This is a fully onsite position in Houston, TX.

Application Deadline:

This position is anticipated to close on Aug 14, 2026.

About Actalent:

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email View email address on click.appcast.io for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.