Pharma Project Manager

Located in Thousand Oaks, California, 20BLOC is a small privately held development-stage biopharmaceutical company, driven by a mission to create breakthrough protein-based drugs to save lives. Our lead product is an innovative solution to provide oxygen to tissues. Check us out at

We are looking for a motivated and hands-on Pharma Project Manager to join our team.

How you will add value to 20BLOC

The Pharma Project Manager supports the Clinical and Commercial function by managing projects for R&D, non-clinical, and clinical programs. This role will help drive cross-functional execution of drug development programs in a fast-paced startup environment. The Pharma Project Manager works closely with R&D, clinical, regulatory, and other cross-functional teams to ensure teams are aware of and completing tasks ahead of schedule on the critical path. This role requires a highly adaptable, hands-on leader who can operate with limited resources and accelerate programs from early development through key regulatory milestones.

Key Responsibilities

Project Planning & Execution

• Build and maintain integrated project plans across R&D, CMC, regulatory, and clinical functions with clear dependencies, critical path, and scenario analyses
• Identify critical path activities and proactively manage risks, trade-offs, and resource constraints
• Continuously refine timelines based on new data, regulatory feedback, and technical risks

Regulatory

• Track regulatory commitments, milestones, and agency interactions
• Ensure project plans align with regulatory expectations from agencies like the FDA

External Partner & Vendor Management

• Lead oversight of CROs, CDMOs, and consultants and ensure accountability to timelines and deliverables
• Ensure quality and regulatory compliance in outsourced activities

Process Development & Continuous Improvement

• Introduce tools (e.g., MS Projects) and standard templates
• Scale processes as the organization grows

Cross Functional Support

• Align scientific, clinical, and operational teams around shared milestones
• Facilitate structured decision-making in ambiguous or conflicting situations

Resource & Budget Management

• Contribute to operational scaling as the company grows (e.g., budgeting, resource planning, SOP development)
• Optimize allocation of limited resources to maintain critical path progress

Education

• Bachelor’s degree in Life Sciences or a related field
• Advanced degree preferred, including M.S., MBA, Pharm.D., or Ph.D. in a scientific, engineering, or business-related field

Experience

• 4 years+ of experience in pharma/biotech
• Prior experience building PM processes within a startup, emerging biotechnology company, or high-growth environment strongly preferred
• Demonstrated experience managing complex, cross-functional programs involving multiple stakeholders, timelines, and external partners

Skills & Competencies

• Strong understanding of the drug development lifecycle
• Familiarity with GxP environments (GMP, GCP, GLP)
• Proficiency in project management software (MS Project, Smartsheet), understanding of drug development pathways, and financial acumen
• PMP certification (from Project Management Institute) is a plus but not required
• High attention to detail and strong documentation skills
• Strong organizational and time management skills
• Effective written and verbal communication skills
• Ability to work independently and collaboratively in a team environment

Please apply at ***email_hidden*** – in subject line: Pharma Project Manager

This is a full-time, on-site position located in Thousand Oaks, California, and requires working on-site Monday through Friday. All applicants must be authorized to work in the United States. We are not sponsoring employment visas.

Compensation: The salary range for this position is $100,000.00. to $140,000.00 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.

20BLOC is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status, or other applicable legally protected characteristics.

We offer competitive compensation and benefits including health, dental, vision and life insurance, 401(k) and paid time off.