Manager, Accounting

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

As Manager, Accounting you will oversee the daily operations of the company's accounting function, ensuring accurate, timely, and compliant financial reporting and accounting operations in a fast-paced, high-growth environment. You will lead and develop the accounting team, manage high-volume transactional processes and month-end close activities, maintain strong internal controls, and partner cross-functionally to support the company's continued growth and operational execution.

Essential Duties & Key Responsibilities

• Oversee all aspects of the accounting function, ensuring accurate, timely, and compliant financial reporting while supporting the organization's strategic and operational objectives.
• Manage and maintain the general ledger, including preparing and reviewing journal entries within assigned areas of responsibility.
• Develop and maintain a comprehensive understanding of the company's financial reporting processes and general ledger structure.
• Ensure compliance with internal accounting policies, procedures, GAAP standards, and applicable regulatory requirements.
• Lead, mentor, and supervise accounting staff, while driving improvements and enhancing operational efficiency.
• Coordinate and support external audit activities, including annual financial statement audits, quarterly reviews, and internal control testing.
• Oversee statutory and regulatory filings in accordance with local jurisdiction requirements, including but not limited to 1099 reporting, sales and use tax, property tax, and census reporting.
• Experience with clinical trial accounting and accrual management is preferred but not required.
• Proficiency with ERP systems, preferably NetSuite and strong knowledge of accounting software and financial reporting tools.

Minimum Experience, Education, Certifications, Licenses

• Bachelor's degree in Accounting, Finance, or related field; CPA preferred.
• 5+ years of progressive accounting experience within biotechnology or life sciences.
• Prior people management experience required, including leading and developing accounting staff and driving accountability/performance.
• Strong knowledge of day-to-day accounting operations, including accounts payable, general ledger, monthly close, accruals, and statutory/compliance filings.
• Experience managing high-volume AP and operational accounting workflows in a fast-paced environment.
• Demonstrated ability to operate with firmness and accountability while building effective cross-functional relationships.
• Strong organizational skills, attention to detail, and ability to prioritize across competing deadlines.
• Experience with ERP/accounting systems and Microsoft Excel.

$125,000 - $155,000 a year

The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.

Who we are

We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.

We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.

We innovate on a path that hasn't been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren't afraid to ask "why not" and challenge the status quo.

We maintain a start-up culture of camaraderie and leadership by example, regardless of title.

We're proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.

Notice to staffing firms

Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.