Chief of Staff
Talentpluto
Chief Of Staff
Location: San Francisco, CA
Work Model: Hybrid
Industry: AI Infrastructure / Conversational AI
Compensation: Competitive base and OTE, commensurate with experience
Our partner is a fast-growing, seed-stage AI infrastructure startup building an end-to-end testing and observability platform for conversational AI, spanning both voice and chat agents. In under a year they have surpassed seven figures in ARR, backed by top-tier investors, and count global enterprises and Fortune 500 brands among their customers.
As Chief of Staff, you will work directly alongside the CEO of a fast-growing AI infrastructure startup, operating as a high-caliber generalist across strategy, operations, and execution. This is a high-agency, high-trust role for someone who thrives on ambiguity and outsized ownership.
You will act as a force multiplier for the leadership team, stepping into the highest-priority problems wherever the business needs them most.
Partner directly with the CEO on strategy, operations, and special projects.
Drive cross-functional initiatives from idea to execution.
Bring structure and rigor to decision-making and planning.
Operate as a force multiplier across the leadership team.
Take on high-priority problems wherever the business needs them.
Exceptional caliber and range, with the ability to operate across strategy and operations.
A background such as top-tier finance, consulting, or operations, often paired with an MBA.
High agency and comfort with ambiguity and shifting priorities.
Experience at a pre-Series C startup preferred, with a track record of wearing multiple hats.
Able to work onsite in San Francisco five days per week.
Vacancy posted 4 hours ago
Similar jobs that could be interesting for youBased on the Chief of Staff in San Francisco, CA vacancy
$135k - $175k
...Capital and NVP Capital, looking for builders who want to solve hard problems. The Role & Culture We are seeking a sharp, organized Chief of Staff to support HomeVision’s CEO and company operations. This role is focused on acting as a strategic operational partner to the...SuggestedFlexible hoursHomeVision
San Francisco, CA2 days ago- ..., Coinbase, and Palantir, among others Build a massive, fast-growing business with billions in revenue The Role The Chief of Staff to the CEO is Garrett Lord's closest execution partner - the person who helps him get things done at extraordinary speed across...SuggestedFull timeFreelanceInternshipWork at officeRemote workFlexible hours
Handshake
San Francisco, CA3 days ago - ...that someone else sold back. So that's what we make: a liquid market for GPU offtake. About TheRole SF Compute is seeking a Chief of Staff to the CEO to serve as a strategic partner and force multiplier to the CEO. This role combines strategy, operations, and execution...SuggestedLong term contractContract workFixed term contractWork at officeLocal areaVisa sponsorshipShift work
SF Compute
San Francisco, CA1 day ago - The Role Pair directly with the CEO to scale the company and its impact on patients across the country. Be their force multiplier. Make them 2x more effective, every day. 5 days a week in person in San Francisco. Scope You'll span every topic the CEO touches: ...SuggestedWork experience placement
Healthleap AI
San Francisco, CA2 days ago - ...Chief Of Staff To The CEO This is Chief of Staff to Sam Rodriques, Edison Scientific's co-founder and CEO. This role is one of the highest-leverage seats in the company: you will sit next to Sam, with a front-row view of how Edison is built and how we are accelerating...SuggestedWork at office
Edison Scientific Inc.
San Francisco, CA2 days ago - ...running and grown a high-caliber team turning the art of sales into a scalable science. About the Role We're looking for a Chief of Staff who will operate as a true extension of the CEO. This is a rare opportunity to work directly alongside the CEO and gain an...
Nooks
San Francisco, CA2 days ago - ...Important note: this hiring process is being managed by Hike's current Chief of Staff who is being promoted into a new role. About Hike Medical Hike Medical is building the defining company in musculoskeletal care. We sit at the intersection of AI, robotics, and...Work at officeRelocation package
Hike Medical
San Francisco, CA4 days ago - ...in Denver, CO, and San Francisco, CA. The specific responsibilities and requirements are detailed in the full job description. Chief of Staff role supporting the CEO at Checkr. This position is based in San Francisco, California, and involves high-level strategic support...Work at office
Oppurtuna
San Francisco, CA5 days ago - ...Triumph is looking for a Chief of Staff to partner directly with our VP of Engineering. This is a high-impact, execution-focused role for someone who thrives in ambiguity, moves fast, and knows how to get things done across a complex organization. You’ll be the connective...
Triumph
San Francisco, CA3 days ago - ...Overview Chief of Staff to the SVP, Permanent Full-time job opportunity, San Francisco Bay Area, US. Avataar is a global GenAI visualization company revolutionizing the retail industry with spatial storytelling. Our AI-led Computer Vision platform enables interactive...Permanent employmentFull time
Turbohire Technologies Pvt Ltd
San Francisco, CA5 days ago - ...Foundation Capital , we’re transforming how enterprises protect their people from modern social engineering threats. The Role As Chief of Staff , you will be the primary force multiplier for our CEO and the founding team. You are an operator tasked with ensuring the...Permanent employment
Cerebras
San Francisco, CA4 days ago - ...Overview Join to apply for the Chief of Staff role at Heliux . Heliux is a software platform that unifies and accelerates enterprise-wide operations for manufacturers. Our centralized operating system models cross-functional teams, workflows, and data into a single system...Permanent employmentFull time
Heliux
San Francisco, CA4 days ago $200k - $240k
...including institutions such as Cleveland Clinic, Duke, Stanford, and Johns Hopkins. About The Role AKASA is looking for an exceptional Chief of Staff to report directly to the COO and serve as a strategic partner and force multiplier to the broader executive leadership team....Home officeFlexible hoursAKASA
San Francisco, CA2 days ago$281k - $330k
...highly strategic role, you will partner with executives and senior leaders both across the business and within the Product org. As Chief of Staff reporting directly to the CPO, you will have an immediate impact on our CPO's productivity from day one, streamlining...Work at officeLocal areaImmediate startRemote workRelocationFlexible hours3 days per weekCheckr
San Francisco, CA4 days ago- ...As Chief of Staff at Emanate, you'll work directly with the founder to turn company priorities into execution across hiring, operations, GTM, finance, and team systems. You'll bring structure to fast-moving work-streams, drive follow-through on critical decisions, and...
Emanate
San Francisco, CA4 days ago - ...Chief Of Staff Exa is an applied AI lab building a search engine unlike the world has ever seen. We build massive-scale infra to crawl the entire web, train state-of-the-art embedding models to process it, and design super high performant vector databases to retrieve...H1b
Exa Labs
San Francisco, CA2 days ago - ...Chief Of Staff We're looking for a Chief Of Staff who is highly driven, organized, comfortable with ambiguity, and excited to join us in-person in San Francisco to help build and scale the company. You'll work directly with the CEO and set the cadence for how the...
Variance
San Francisco, CA2 days ago - Helium is a fast‑growing AI company focused on self‑improving software. We are looking for a dynamic operations partner to support the CEO in scaling the business. Responsibilities Act as the CEO’s force multiplier, taking on strategic projects and running them end ‑to‑...Night shift
Helium
San Francisco, CA2 days ago - ...About the Role Our Client is hiring a Chief of Staff to be the CEO's right hand. The team is growing extremely fast and needs a force multiplier who can take strategic projects and run them end-to-end across growth, fundraising, hiring, expansion, customer success, and...Shift workNight shiftDay shift
Product Pulse
San Francisco, CA2 days ago $165k - $205k
...scaling rapidly and building the foundation for a new era of high-performance, Made in America production. About the role: The Chief of Staff is a high-output operator who works directly with the CEO to drive execution across Formic’s highest-priority initiatives. This...Hourly payFull timeTemporary workRemote workHome officeShift work3M HEALTHCARE
San Francisco, CA5 days ago- ...processes, and drive execution in fast-paced startup environments Experience managing internal operations, team coordination, or chief of staff responsibilities at high-growth companies Strong analytical skills with ability to work across both quantitative analysis and...
Casca
San Francisco, CA5 days ago $200k - $250k
...frontier of what Agentic AI can do in production — we ship real systems that run real business processes at scale. Role Overview As Chief of Staff to the CEO, you will be the strategic nerve center of the entire company — a true force‑multiplier to Surojit Chatterjee (ex...Work at officeWorldwideRelocationEMA
San Francisco, CA2 days ago$220k - $345k
...Senior Operator, Chief Of Staff To The President The Center for AI Safety (CAIS) is a leading research and advocacy organization focused on mitigating societal-scale risks from AI. We address AI's toughest challenges through technical research, field-building initiatives...Contract workWork at officeLocal areaShift workCenter for AI Safety
San Francisco, CA3 days ago- ...the role Mixedbread has shipped a major new version of its product and is gaining traction with customers. We're looking for a Chief of Staff to help the founders keep the company focused, organized, and moving. This role spans execution, operations, hiring, and strategic...
MixedBread AI
San Francisco, CA4 days ago $110k - $160k
...talent at innovative companies. Our team is 100% remote and we work with teams across the United States to help them hire. Chief of Staff Location: San Francisco, CA (On-site) Company Stage of Funding: Seed Stage Office Type: In-person 5 days/week Salary...Work at officeRemote workVisa sponsorshipRecruiting from Scratch
San Francisco, CA2 days ago$120k - $160k
...top-tier firm (Goldman, Evercore, Morgan Stanley, JP Morgan, Lazard, Centerview, PJT) with 1-2 years tenure. Strategic ops or chief of staff at a top-tier startup with demonstrated 0-1 ownership and direct founder access. Top university pedigree (MIT, Harvard, Berkeley...Full timeTemporary workInternshipWork at officeVisa sponsorshipRelocation packageDavid Joseph & Company
San Francisco, CA22 hours ago- ...Chief Of Staff, Strategic Growth Initiatives Location: West Coast–Based (San Francisco or Seattle preferred) Reports to: Chief Client & Growth Officer Role Purpose: The Chief of Staff serves as the operating backbone of a high-priority, multi-workstream strategic...
Talentry LLC
San Francisco, CA3 days ago - About Roger Roger is an AI platform that frees home health clinicians from paperwork so they can focus on what matters: delivering life-changing care to our most vulnerable elderly patients in the comfort of their homes. Backed by leading healthcare investors like...Flexible hours
Roger Healthcare
San Francisco, CA3 days ago $90k - $150k
Overview This is a high-ownership role for someone who wants to sit close to the center of a fast-moving company and turn ambiguity into shipped work. This is not a note-taking job. You will own messy, important projects from first principles: customer discovery, sales...Cranston AI (YC F25)
San Francisco, CA2 days ago- ...top-tier investors and led by an experienced, scrappy founding team scaling from seed stage toward Series A. We're looking for a Chief of Staff to partner directly with the CEO and founding team to drive company strategy, OKRs, and execution across product, growth,...Work at office
MaxHome
San Francisco, CA2 days ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Chief of Staff. Be the first to apply!
