Clinical Trial Manager

J oin Immatics and s hape the f uture of c ancer i mmunotherapy ; one patient at a time !

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities spanning TCR T-cell therapies and TCR bispecifics .

Why Join Us

• Innovative Environment : Help to pioneer advancements in cancer immunotherapy.

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.

• Global Impact : Contribute to therapies that make a lasting impact on patient s globally .

Role Overview :

We are seeking a Clinical Trial Manager (CTM) to support our U.S. Clinical Operations team. The CTM will oversee site management monitoring oversight and clinical trial operations activities to ensure compliance with GCP regulatory requirements and company this role you will work closely with cross-functional teams and clinical sites to drive study execution site engagement and operational excellence across clinical trials.

Reports to : Associate Director Team Lead Site Operations
Location : Fully Remote

Salary Range: $130000 - $150000

Basic Qualification s :

• Bachelors degree in life sciences nursing or a related field

• 2 years of experience in on-site clinical monitoring and 2 years of Clinical Trial Manager experience within the pharmaceutical or biotechnology industry

• Strong knowledge of ICH-GCP FDA EMA and applicable clinical trial regulations

• Demonstrated experience managing clinical trial sites monitoring activities and regulatory documentation

• Proficiency with clinical trial systems and tools (e.g. CTMS eTMF Microsoft Office)

Preferred Qualifications :

• Experience in oncology clinical trials or related therapeutic areas

• Advanced ability to manage complex clinical operations processes and drive operational improvements

• Experience leading training initiatives for CRAs and clinical trial sites

• Demonstrated ability to drive quality efficiency and milestone achievement in fast-paced clinical environments

• Experience contributing to process harmonization innovation and continuous improvement initiatives

• Strong presentation organizational and cross-functional stakeholder management skills

In this r ole you w ill :

• Partner with Clinical Operations leadership to support clinical trial execution and monitoring activities in alignment with project goals

• Lead site feasibility selection initiation and greenlight activities for clinical trial sites

• Develop and maintain study-specific operational plans training materials and monitoring documentation

• Oversee site management activities including site engagement regulatory submissions and monitoring oversight

• Review trial progress patient recruitment and data quality metrics and implement actions to support study objectives

• Provide guidance and oversight to CRAs including trip report review and training support

• Manage protocol and GCP deviations and contribute to continuous improvement of clinical operations processes and procedures

Travel required: up to 50% travel domestically and internationally .

Qualified candidates will participate in a structured interview process which includes:

• An initial recruiter phone screen (conducted via video)

• A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)

• A final-stage interview which may include an in-person meeting at our U.S. Headquarters in Houston TX

Wh at do we offer

At Immatics we believe in investing in our team s health safety and well-being . Heres what you can expect if you join Immatics

Comprehensive Benefits :

• Competitive rates for Health Dental and Vision Insurance

• 4 weeks of vacation granted up front each year and prorated for first and last year of employment.

• 12 company paid holidays

• 7 days of sick time

• 100% e mployer- p aid l ife i nsurance up to at 1x annual salary up to one hundred thousand dollars

• 100% e mployer -p aid s hort- and l ong-Term d isability c overage

• 401(k) with i mmediate e ligibility and company mat ch

• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employmen t 4% for years 2-3 of employment and up to 5% of your salary from the fourth year onward of continued employment.

• P artially paid p arental l eave for eligible employees.

• Additional voluntary employee - paid benefits and services including a ccident h ospital i ndemnity and c ritical i llness insurance as well as i dentity t heft p rotection and p et i nsurance .

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace . We consider all qualified applicants for employment without regard to race color religion sex (including pregnancy childbirth or related medical conditions) sexual orientation gender identity or expression national origin ancestry age marital status disability genetic information veteran status or any other st atus protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs practices or observances . If you require assistance or accommodation during the application or interview process please contact us at

Required Experience:

Manager