Sr. Upstream Processing Technician

Job Title: Upstream Processing TechnicianJob Description

Join a dynamic team in the pharmaceutical industry, supporting the manufacture of commercial and clinical biologics. As an Upstream Processing Technician, you will follow Current Good Manufacturing Practices (cGMPs) to perform various functions related to upstream cell culture, including mammalian cell propagation, aseptic operations, and large-scale bioreactor production.

Responsibilities

• Review all area documents.

• Manage the WNS.

• Assist in the manufacture of controls and calibrators, completing batch records in compliance with cGMPs.

• Perform in-process assays using equipment such as spectrophotometers, pH meters, and clinical analyzers.

• Weigh, transfer, and mix chemicals.

• Conduct product filtrations.

• Clean and steam steel tanks (CIP/SIP).

• Prepare glassware and steel tanks for sterilization in an autoclave and operate the autoclave.

• Maintain lab equipment including pumps, pH meters, and flow meters.

• Keep department lead or manager updated on all issues.

• Monitor stocks of common lab supplies.

• Respond to emergency notifications.

• Perform other job duties as required.

• Be flexible with working hours, including weekends.

Essential Skills

• Experience in a cGMP regulated environment and proficiency in aseptic techniques.

• Bachelor's Degree in Science with expertise in aseptic techniques, cell culturing, and pipetting.

• Minimum of 2 years of work experience in manufacturing, operations, production, lab settings, or related fields.

Additional Skills & Qualifications

• Preferred: Experience in a cGMP environment and a 4-year STEM degree.

• Knowledge of cGMP practices, aseptic techniques, or chemical concepts is advantageous.

• Subject Matter Expertise in upstream processing steps is preferred.

Work Environment

Work in a cleanroom/aseptic suite environment, requiring full gowning, including bodysuit, gloves, hair & beard nets, face covers, and safety glasses. Adhere to cleanroom protocols, prohibiting makeup, jewelry, nail polish, cologne/perfume, and scented lotions or hair care products. The role involves working on a rotating 10-hour shift schedule, 40 hours a week, with the ability to lift a minimum of 25 lbs independently and stand for 80% of the shift.

Job Type & Location

This is a Contract to Hire position based out of Saint Louis, MO.

Pay and Benefits

The pay range for this position is $30.80 - $30.80/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: - Medical, dental & vision - Critical Illness, Accident, and Hospital - 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available - Life Insurance (Voluntary Life & AD&D for the employee and dependents) - Short and long-term disability - Health Spending Account (HSA) - Transportation benefits - Employee Assistance Program - Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Saint Louis,MO.

Application Deadline

This position is anticipated to close on Jun 29, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email View email address on click.appcast.io for other accommodation options.

San Francisco Fair Chance Ordinance: Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI): We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.