Principal Scientist

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.Position SummaryTranslational Development is part of the Global Research organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics. Key Responsibilities:Designs and implements program-specific late development biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicableManages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROsPrepares and delivers internal and external translational/biomarker presentationsMaintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as neededKeeps up-to-date on relevant scientific/technical literature in order to applyingexternalknowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biologyWorks with TM laboratory scientists and academic TLs to address nonclinical translational questionsParticipates in post-hoc biomarker analysis and publication effortsSupports regulatory submissions and regulatory interactions as neededQualifications & Experience:PhD or MD/PhD in neuroscience with 7+ years of translational medicine experience5+ years of late stage clinical biomarker experience in biotech/pharmaRecognized expertise in translational biomarkers in neuroscience spaceExperience in late-stage drug development and activities required for and related to clinical trial initiation, maintenance and completionStrong verbal and written communication skillsExperience in interacting with CROs and TLs to manage projects and timelinesProven scientific/leadership expertise (working in teams, mentoring people, managing projects)Accountable for timelines and deliverablesPrioritizes risks and implements contingency plansCommunicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requestedRecognizes cross-functional issues and communicates within the larger organization. Provides expert guidance to multi-disciplinary teams and senior management. Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.Ability to prioritize and manage time efficientlyAccurate and detailed record keepingExcellent organizational skills#LI-HybridWe hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.Compensation Overview:Brisbane - CA - US: $184,060 - $223,036 Cambridge Crossing: $184,060 - $223,036 Princeton - NJ - US: $160,060 - $193,949 San Diego - CA - US: $176,050 - $213,334 The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.Benefits:Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.U.S.-based job seekers can explore full benefit offerings at How We WorkWhere you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at Supporting People with DisabilitiesBMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplaceaccommodations/adjustmentsand ongoing support in their roles. Applicants can request a reasonable workplaceaccommodation/adjustmentprior to accepting a job offer. If you require reasonableaccommodations/adjustmentsin completing this application, or in any part of the recruitment process, direct your inquiries to Visitcareers.bms.com/eeo-accessibilityto access our complete Equal Employment Opportunity statement.Candidate RightsBMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:Data ProtectionWe will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.If this posting is missing required information required by local law or incorrect, contact BMS at the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.R : Senior Principal Scientist, Neuroscience, Clinical Biomarker, Late Phases, Translational MedicineSummaryLocation: San Diego - CA - US; Brisbane - CA - US; Princeton - NJ - US; Cambridge Crossing - MA - USType: Full time RayzeBio