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Principal Scientist

Scorpion Therapeutics

Role: Principal Scientist leading antibody engineering initiatives within Bristol Myers Squibb's Therapeutic Discovery Sciences Department, focusing on early-stage research and platform technology development for recombinant antibody therapeutics. Responsibilities: design, execute, and troubleshoot workflows for affinity maturation, humanization, format conversion, and characterization of diverse antibody formats (IgG, Fab, scFv, bispecifics) analyze biophysical properties using SEC, SPR/BLI collaborate across discovery, structural biology, computational biology, and other teams evaluate emerging technologies including AI/ML author technical documentation and lead scientific discussions. Requirements: PhD in protein science, structural biology, biochemistry, or related field 4+ years of relevant industry or academic experience hands-on expertise in antibody design, expression, purification, and characterization experience with protein interaction assays like SPR/BLI proven independent experiment planning and troubleshooting skills scientific leadership with impactful publications or patents. Preferred: experience with advanced antibody formats, bioinformatics, structural techniques, and therapeutic areas such as oncology or immunology prior biotech or pharma experience. HighValue: biologics antibody engineering early discovery biophysical characterization platform development cross-disciplinary collaboration. Work setup: laboratory-based role in San Diego, CA. #J-18808-Ljbffr Scorpion Therapeutics

Vacancy posted 1 day ago
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