Bioinformatics, Senior Scientist, ctDNA

Senior Bioinformatics Scientist ( ctDNA ), San Diego, CA / Remote (US) - $150,000 - $180,000

Are you passionate about advancing cancer diagnostics through cutting-edge bioinformatics and testing? Our client, an innovative biotechnology company focused on molecular diagnostics, is seeking a Senior Bioinformatics Scientist to lead the development of next-generation laboratory-developed tests in a highly collaborative and regulated environment.

Who you are:

• PhD in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a related quantitative field (or MS plus additional industry experience).
• 6+ years of experience in biotech, diagnostics, or regulated healthcare environments.
• Hands-on experience developing NGS-based clinical assays, including ctDNA and MRD applications are a must.
• Strong Python programming skills with experience building production-grade bioinformatics pipelines and following SDLC best practices.
• Proven success working within CAP/CLIA, IVD, FDA, or similarly regulated development environments.

What you'll do:

• Lead bioinformatics strategy, development, optimization, and validation efforts for MRD diagnostic assays.
• Design and execute analytical studies evaluating assay performance, including sensitivity, accuracy, reproducibility, and limit of detection.
• Develop and maintain scalable bioinformatics pipelines for QC, variant calling, MRD detection, and reporting.
• Collaborate with assay development, clinical, quality, regulatory, software, and data science teams to deliver validated solutions.
• Mentor junior scientists and contribute to technical documentation, audits, and regulatory submissions.

What does this position pay?

Compensation is determined by several factors which may include skillset, experience level, and education.

The expected range for this role is $150,000-$180,000 per year. Please note this range is an estimate and actual pay may vary based on qualifications and experience.

What's next?

Please email your resume to View email address on apply.j-vers.com if you're excited to explore this opportunity with our client.

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