Lead Translational PK/PD Scientist — Hybrid
Merck
Merck is seeking a Translational PK/PD Associate Director within our PDMB Translational PK/PD organization in the US. This role focuses on biologics, protein therapeutics, and peptides, applying expert PK/PD modeling to guide drug discovery decisions. The successful candidate will integrate in vitro and in vivo data to build PKPD and QSP models, design studies, and lead automated workflows. Collaboration across disciplines and mentoring junior colleagues are essential. #J-18808-Ljbffr Merck
$129k - $203.1k
...(PDMB) is seeking a curious and collaborative Senior Scientist for our growing Translational PK/PD organization. The Translational PK/PD Senior Scientist... ...Yes Travel Requirements 10% Flexible Work Arrangements Hybrid Shift 1st - Day Valid Driving License No Hazardous Material...SuggestedFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$129k - $203.1k
The Translational PK/PD Senior Scientist will: Serve as PK/PD modeler in cross-functional teams to support model-informed decisions on drug discovery, modality selection, and dose prediction. Integrate in vitro and in vivo data to build PKPD, PBPK, QSP, and other mechanistic...Suggested- Scorpion Therapeutics in Boston seeks a Translational PK/PD Senior Scientist to drive model-informed decisions across drug discovery and dose prediction. The role integrates PKPD modeling with experimental data, supporting forward and reverse translation and informing...Suggested
- ...Therapeutics is seeking a Discovery ADME Project Leader to deliver a deep mechanistic understanding of drug disposition and translational PK/PD modeling that informs dose selection and study design. You will integrate biology, chemistry, and modeling within cross-functional...Suggested
$119.7k - $222.3k
...enthusiastic and motivated PK Sciences representative to lead the development and use of... ...to work seamlessly in the translational and/or clinical space,... ...nonclinical and clinical PK/PD relationships and development... ...considered for Principal Scientist II. 4+ years of experience...SuggestedFull time$114.1k - $211.9k
...seeking a highly motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative and strategic... ...programs. In addition, we provide flexible and hybrid working options, where possible, and a minimum of 14 weeks...Full timeLocal areaFlexible hours- ...biotherapeutics development go hand in hand. As a Scientist, PK/PD Modeling & Simulation, you will be... ...closely with internal cross-functional leads (clinical pharmacology, nonclinical,... ...preclinical and clinical PK/PD data, translating insights into actionable...
- ...seeks a Director of Clinical Pharmacology to lead strategic, scientific and operational... ...pharmacology plans, supervise asset leads and guide PK analyses. The role requires leading... ...regulatory and safety documents, contributing to PK/PD modeling and staff career development, with...
$108.5k - $201.5k
Summary #LI_Hybrid Location:... ...enthusiastic and motivated PK Sciences project... ...and implement translational or clinical pharmacology... ...of PK/PD relationships and develop... ...experience preferably in a lead role overseeing... ...considered for Principal Scientist II • Extensive...- Alnylam Pharmaceuticals, Inc. in Cambridge, MA is seeking a DMPK Scientist to design and interpret in vitro and in vivo ADME and PK/PD studies for siRNA and other modalities, informing human dose projections and candidate selection. You will build quantitative models and...
- Hemab is seeking a Scientist, PK/PD Modeling & Simulation in Cambridge, MA to develop population PK/PD, PBPK and QSP models to support dose selection and trial design. You will collaborate with clinical pharmacology, nonclinical, and regulatory teams to inform clinical...
- Alnylam Pharmaceuticals in Cambridge, MA seeks a DMPK Scientist to design and interpret ADME and PK/PD studies for siRNA and other modalities, applying quantitative pharmacology to guide candidate selection and human dose predictions. The role demands expertise in non-...
- ...Job Description Job Description Scientist/Senior Scientist, Biology Lead – Kidney Experience About the... ...biology, renal disease mechanisms, and translationally relevant kidney disease models to... ...knockdown ü In vivo PK/PD, biodistribution, efficacy, and biomarker...
- ...seeks a Director, Clinical Pharmacology to lead strategic, scientific and operational... ...management. You will supervise asset leads, guide PK/PD analyses, oversee regulatory documents,... ...program reviews and initiatives. Hybrid or on-site work options available. #J-188...
- Merck in Boston, MA is seeking a Translational PK/PD Senior Scientist to design and execute modeling analyses that guide drug discovery for biologics... ...collaborating across Discovery and Translational divisions while leading or contributing to mechanistic modeling projects with...
- Hebrew SeniorLife’s Marcus Institute for Aging Research in Boston seeks a Senior Scientist in ADRD to expand its clinical research program and translation efforts. The appointment may include a Harvard Medical School faculty rank, commensurate with teaching responsibilities...
$89.6k - $166.4k
...OnsiteLocation: CambridgeInternal Title: Senior Scientist ISupport discovery and development projects through... ...metabolic stability and permeability to support PK Science’s strategies.Interpret in vitro ADME data and translate findings to support early discovery, compound...Full time$126k - $234k
...Description Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior... ...therapies. We are seeking a translational modeler eager to... ...and mechanistic PBPK/PD approaches to inform... ...Simulation (M&S) team lead within the... ...mechanistic models (PK/PD, QSP, and PBPK/PD...Full time- ...Inc. seeks a strategic, hands-on Biomarkers Senior Research Lab Scientist to develop and optimize biomarker assays for clinical trials.... ...tissues, working closely with Research, Quality, and Biomarker Leads in a fast-paced, agile environment. You will lead method development...
- Flagship Pioneering is looking for a Senior Scientist to join their research team in Cambridge, Massachusetts. The ideal candidate will have a Ph.D. and experience in cell isolation, flow cytometry, and in vivo mouse studies. This position involves designing and executing...
- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...
- ...supports cross-functional teams and may represent Medical Writing Science in study- and program-level activities. The position is hybrid, with 2 days remote per week and 3 days in the Boston Fan Pier office, offering flexible designations for Hybrid/On-Site work. #J-...Work at officeRemote workFlexible hours2 days per week
$178.5k - $257.83k
Job title: Health Value Translation LeadLocation: Cambridge, MAAbout the jobJoin the engine... .... As Health Value Translation (HVT) Lead within our Patient Driven Medicines Development... ...protected by law. #GD-SA #LI-SA #LI-Hybrid#vhdPursue progress, discover extraordinaryBetter...Full timeWork experience placementLocal area$142.22k - $172.34k
...sites in Cambridge and Seattle, scientists focus on novel targets and... ...drug discovery through translational and early clinical development... ...translational expertise, biology and leading academic research centers in... ...roles may be eligible for a hybrid work model with at least 50%...Hourly payFull timeContract workTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$100k - $120k
...StealthCo - Associate Scientist, In Vitro... ...focus offers strong translatability from animal models... ...vivo pharmacology lead. The two are connected... ...engagement and PD effect across delivery... ...data anchoring PK/PD interpretation... ...immunohistochemistry, in situ hybridization, microscopy,...Shift work$105.04k - $127.29k
...59 : Senior Associate Scientist, In Vivo Pharmacology,... ...drug discovery through translational and early clinical... ...expertise, biology and leading academic research centers... ...in vivo efficacy and PK/PD studies and experiments... ...may be eligible for a hybrid work model with at...Hourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$111k - $189k
The Lead Strategic Partnership Data Analyst turns data into clear, actionable insights... ...visualization and executive-ready presentations, translating complex findings into clear stories and... ...the internal mobility guidelines in the hybrid policy reference guide for more...Full timeWork at officeLocal areaRelocationRelocation packageFlexible hours$260.3k - $409.7k
...opportunity for a physician-scientist to join our group as a- Principal... ...(Clinical Director) in Translational Medicine/Early Clinical Development... ...strategy Taking a lead role in developing and executing... ...Flexible Work Arrangements: Hybrid Shift: Not Indicated...Full timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work- ...pharmacokinetic/pharmacodynamic (PK/PD) relationships of... ...and Development as a Principal Scientist within Drug Metabolism and Pharmacokinetics... ..., candidate selection, translational research, and clinical... ...and governance discussions.• Lead or contribute to the preparation...Full timeTemporary workWork at officeLocal areaFlexible hours
$146k - $236k
...in human health, sustainability, and beyond.About the Role Pioneering Intelligence (PI) is building AI systems that accelerate translational decision making. This forward-deployed role bridges the gap from capability to impact by leveraging PI technologies to take on translational...
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