Postdoctoral Associate

Job Description The Ye Lab is seeking a highly motivated Postdoctoral Associate to join our team and contribute to an NIH-funded project focused on understanding how glioma hijacks the tumor microenvironment to drive malignant progression. Our research lies at the intersection of glial biology and brain cancer, with a particular emphasis on malignant glioma, the most aggressive form of primary brain tumor. The successful candidate will investigate the role of astrocytes—one of the most abundant and functionally diverse types of glial cells—in glioma progression and their modulation of the tumor microenvironment. The project will employ genetically engineered mouse and human glioma models, along with advanced imaging techniques, single-cell and spatial transcriptomics, and molecular biology approaches. The Postdoctoral Associate is expected to lead research projects from experimental design, data analysis, to presentations in lab meetings, conferences, and seminars, as well as prepare manuscripts for peer-reviewed publications. Additionally, the candidate will contribute to mentoring research technicians and students involved in the project. We are committed to supporting your career development by building on your existing expertise while providing opportunities to gain new skills in a collaborative and productive research environment. Required Qualifications Ph.D. in Biology, Neuroscience, or a related field. PhD must be awarded no more than four years prior to the effective date of appointment with a minimum of one year eligibility remaining. Experience with in vivo research involving mouse Proficiency in immunostaining and fluorescence microscopy Familiarity with basic molecular biology techniques (e.g., cloning, Western blotting) Experience with mammalian cell culture Track record of first-author publication(s); preprints are acceptable Preferred Qualifications Hands-on experience with rodent brain surgery Experience with primary cell culture Background in brain cancer, brain injury, or neuroscience research Overtime Status Exempt: Not eligible for overtime Appointment Type Restricted Salary Information Commensurate with experience Hours per week 40+ Review Date 7/21/2025 Additional Information The successful candidate will be required to have a criminal conviction check. About Virginia Tech Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicine college, Graduate School, and Honors College. The university has a significant presence across Virginia, including the Innovation Campus in Northern Virginia; the Health Sciences and Technology Campus in Roanoke; sites in Newport News and Richmond; and numerous Extension offices and research centers. A leading global research institution, Virginia Tech conducts more than $500 million in research annually. Virginia Tech endorses and encourages participation in professional development opportunities and university shared governance. These valuable contributions to university shared governance provide important representation and perspective, along with opportunities for unique and impactful professional development. Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, ethnicity or national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law. If you are an individual with a disability and desire an accommodation, please contact Brittany Shelton at View email address on click.appcast.io during regular business hours at least 10 business days prior to the event. #J-18808-Ljbffr Virginia Tech