Associate Researcher

Title: Research Associate – RNAi Chemical Development

Location: Boulder, CO – Onsite

Schedule: 8:00 AM–5:00 PM, with some flexibility

Duration: 1+ year, with potential extension

Pay Rate: $27/hr on w2

Role Overview

Seeking a Research Associate to support the preparation and delivery of high-quality oligonucleotide starting materials for RNAi manufacturing and process development. This role will work within a cross-functional environment supporting innovation, chemical development, and scale-up activities.

Responsibilities

• Prepare and deliver oligonucleotide starting materials.
• Perform laboratory procedures related to oligonucleotide synthesis, processing, and purification.
• Maintain reliable material supply workflows and laboratory equipment.
• Support ligation development through timely substrate preparation.
• Document laboratory workflows, materials, and activities.
• Identify opportunities to improve efficiency and scalability.
• Collaborate with cross-functional teams involved in chemical development, innovation, API development, and oligonucleotide production.

Requirements

• Bachelor’s or Master’s degree in Chemistry, Biochemistry, Science, Engineering, or a related field .
• 0–3+ years of relevant laboratory experience.
• Familiarity with standard laboratory techniques.
• Strong communication and teamwork skills.
• Positive, willing, and collaborative attitude.

Preferred Qualifications

• Experience with HPLC or LC-MS .
• Familiarity with automated oligonucleotide synthesizers, such as Mermade systems .
• Experience with ion-exchange purification of oligonucleotides.
• Basic understanding of RNAi or oligonucleotide chemistry .