Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Business Operations Lead

Brainco

About Brain Co.

Brain Co. is an applied AI startup co-founded by Jared Kushner and Elad Gil, and backed by leading Silicon Valley builders including Patrick Collison and Andrej Karpathy.
We are building AI applications for the world's most important institutions, delivering impact on real-world problems across governments, healthcare systems, and critical industries.

Our progress so far:
  • Automated construction permitting for a sovereign government → 80% faster, unlocking $375M+ in value
  • Optimized supply chains for a leading global energy company → 30% lower cost, 99% reliability, preventing $100M+ in losses
  • Streamlined hospital patient care across national health systems → 40% better outcomes, 80% less admin work
Company momentum:
  • Raised a $55M Series A from leading investors
  • Built a team of 70+ AI experts from Tesla, Google DeepMind, NVIDIA, and Databricks
At Brain Co., we focus on applying frontier AI to real institutional challenges, working alongside governments, healthcare systems, and critical industries to modernize how essential services operate.
We are looking for leaders who want to help bring new technology into institutions that impact millions of people.

About the Role

We're hiring a Business Operations Lead to build and run the systems that power our internal and go-to-market operations to keep the company moving fast. You'll start hands-on building the foundation, but the role is designed to expand and evolve: the exact scope will shift as the company grows.

You'll move fluidly between designing how something should work and standing it up yourself. You should be senior enough to run things independently, spot what's missing before being asked, and operate to a high standard without hand-holding, and be comfortable with a remit that changes as our needs do.

Key Responsibilities

You'll build the systems that support our company's most important operations, from how the company runs day to day to how we go to market. The areas below are representative rather than fixed; expect the mix to shift as the company grows and as more of this work becomes automated.
  • Own the businesses internal operations, areas like procurement, onboarding, and vendor management, and the processes that hold them together.
  • Build and improve the systems behind our go-to-market, partnering with engineering to make how we sell faster, more consistent, and increasingly automated.
  • Set up systems for smoother deal processes, working cross-functionally with privacy, legal, sales, product, and engineering to help us manage deal volume at scale.
  • Partner with finance and engineering to build the systems and reporting that tie our go-to-market - pipeline, deals, revenue - to how we plan and forecast the business.
  • Replace ad-hoc workarounds with durable, lightweight systems that hold up as the team grows, building the operational plumbing that's currently informal or missing.
  • Identify opportunities to build or improve systems before they become bottlenecks, and think in terms of the infrastructure the company will need as it scales.
  • Make company and team goals legible, and support how we focus our efforts - so the team knows what matters and where to spend its energy.
What We're Looking For

This role is defined more by judgment, ownership, and trajectory than by a specific resume. That said, strong candidates will likely bring:
  • 10-12+ years in Business and/or GTM operations, revenue operations, BizOps, or strategy and operations, with experience building foundations, operating independently, and holding a high standard.
  • An understanding how a go-to-market motion runs including pipeline, enablement, deal flow, with past experience building the systems and infrastructure that make it faster and more consistent.
  • Ability to design and build processes, with a clear sense of how a company should operate as it scales.
  • Ability to work across internal ops, GTM, product, and engineering, and add value quickly without deep domain ramp-up.
  • Ability to design how something should work while also diving into the weeds to stand up the system itself. Low ego, high standards, bias for action.
  • Comfort with ambiguity and experience in how to go from 0 to 1 effectively. They bring structure to undefined problems and building from nothing without waiting for a playbook.
  • Analytically fluency. They are at home with metrics, systems, and data; able to distill complexity into clarity and build processes others can follow.
Nice to Have
  • MBA or equivalent experience.
  • Experience scaling a high-growth startup.
  • Experience with B2B SaaS or recurring-revenue GTM motions.
  • A track record of building systems and working with executive leadership teams.
  • Technical or AI experience, comfort building with, or alongside, AI tools and engineering teams.

Join Us

If you're excited about helping modernize government and bringing frontier AI into the public sector, we'd love to hear from you.

Location

Must be in San Francisco or willing to relocate (hybrid, 3 days/week in office).

Compensation

Competitive compensation including salary, equity, and performance incentives.
Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Business Operations Lead in San Francisco, CA vacancy
  • $230k - $260k

     ...standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to...  ...opportunity to serve as a key partner and advisor on Notion’s Business Operations team, working primarily with our Engineering, Product, and... 
    Suggested
    Local area

    Pat Kelly Engineering

    San Francisco, CA
    8 hours ago
  • $230k - $260k

     ...About The Role This role is a key partner and advisor on Notion's Business Operations team, working primarily with Engineering, Product, and Design. You will identify high‑leverage opportunities, define problems, drive execution, and work directly with senior leadership... 
    Suggested

    Dealhub

    San Francisco, CA
    14 hours ago
  • $155k - $210k

     ...story still has its best chapters ahead. Why this role, why now Business Operations is the connective tissue across Go-to-Market (GTM), Marketing, Finance, Engineering, and Product. As Business Operations Lead , you'll build the systems, analytics, and AI-native workflows... 
    Suggested
    Local area

    Patch

    San Francisco, CA
    4 days ago
  • $175k - $225k

     ...Business Operations Lead San Francisco, California, United States Job Openings Business Operations Lead Business Operations Lead Onsite | San Francisco, CA Direct Hire / Permanent Placement HireNow Staffing is actively recruiting a seasoned, highly skilled... 
    Suggested
    Permanent employment
    Full time

    HireNow Staffing Inc

    San Francisco, CA
    2 days ago
  • $150k - $250k

     ...Business Operations Lead Location: San Francisco Employment Type: Full time Department: Operations Building Open Superintelligence Infrastructure Prime Intellect is building the open superintelligence stack — from frontier agentic models to the infra that enables anyone... 
    Suggested
    Full time
    For contractors
    Remote work
    Visa sponsorship
    Relocation package
    Flexible hours

    Prime-Intellect

    San Francisco, CA
    3 days ago
  •  ...Bizops Lead We believe that software is the foundation of modern civilization. Yet...  ...things at once, from data and analysis to operational execution to cross-functional projects....  ...Will... Support analysis of key business drivers, pulling data, building models,... 
    Work at office
    Relocation

    depthfirst

    San Francisco, CA
    2 days ago
  •  ...About The Role We’re hiring a Business Operations Lead to build and run the systems that power our internal and go‑to‑market operations to keep the company moving fast. You’ll start hands‑on building the foundation, but the role is designed to expand and evolve: the exact... 
    Work at office
    Relocation
    Shift work
    3 days per week

    BRAIN CORP

    San Francisco, CA
    1 day ago
  • $190k - $291k

     ...busywork and focus on what matters. Learn more at superhuman.com and about our values here. The Opportunity We are looking for a Business Operations Lead to partner with leaders across the Managed Growth business and the broader Go-to-Market (GTM) organization to drive... 
    Worldwide
    Home office
    Flexible hours
    2 days per week

    Superhuman

    San Francisco, CA
    1 day ago
  • $137k - $208k

     ...and Austin, which is now home to our US operations. We offer flexibility in how and where you...  ...is to win the hearts and minds of small businesses by bringing their creative ideas to life...  ...the Role As a Business Ops and Strategy Lead, you’ll play a critical role in shaping... 
    Work experience placement
    Work at office
    Relocation
    Flexible hours

    black.ai

    San Francisco, CA
    14 hours ago
  • Aurora Solar is seeking a Senior Business Operations Manager to join our Business Operations team and report to the Director of Business Operations. You will drive end-to-end initiatives, build data-driven insights, and influence across Sales, Marketing, Finance, Product... 

    Aurora-Solar

    San Francisco, CA
    14 hours ago
  • HireNow Staffing is recruiting a seasoned Business Operations professional to join a client partner in San Francisco, CA. This role is designed for a strategic operator who thrives in high-growth environments and builds operational infrastructure where processes do not... 

    HireNow Staffing

    San Francisco, CA
    4 days ago
  • Flint in San Francisco is searching for a Business Operations professional to oversee essential financial and operational functions. You will manage projects that improve efficiency across departments while working closely with the founders. The ideal candidate has 2-5... 

    Flint

    San Francisco, CA
    4 days ago
  • $125.3k - $248.4k

    Principal BizOps & Programs Lead Adobe's Monetization Strategy & Growth team drives hundreds...  ...of Monetization Growth. The role blends operator, strategist, and cross‑functional...  ...What You Bring 10+ years of experience in business operations, strategy, program management,... 
    Local area

    Adobe Inc.

    San Francisco, CA
    2 days ago
  •  ...Backed by General Catalyst and trusted by leading AI labs, high-growth companies, and...  ...foundational hire and help shape how Arphie operates at scale. The Opportunity This is a high...  ...role sitting at the center of Arphie's business. You'll work directly with the founders... 
    Relocation

    Arphie, Inc.

    San Francisco, CA
    4 days ago
  •  ...GitHub Actions substantially faster and cheaper by owning and operating our own global fleet of bare‑metal machines rather than renting...  ...has real impact, and where success in this role can evolve into leading a critical part of the company over time. Enjoy working in person... 

    Blacksmith

    San Francisco, CA
    1 day ago
  • $132k - $208k

    Snorkel AI is looking for a Senior Business Operations Manager in San Francisco, CA (hybrid) to lead strategic initiatives that drive growth. The ideal candidate has over 5 years of experience with strong business judgment and analytical skills. Responsibilities include... 

    Snorkel AI

    San Francisco, CA
    14 hours ago
  • Cardless, a San Francisco-based fintech, is seeking a Business Operations generalist to work directly with our COO on high-priority company initiatives across operations, product, partnerships and finance. You’ll own workstreams end-to-end, jump into what’s most important... 
    Work at office

    Cardless

    San Francisco, CA
    4 days ago
  • $170k - $180k

     ...coordinating across teams, tracking projects, and keeping the company’s operational rhythm running falls on engineers, designers, and product leads. That’s not sustainable, and we know it. As our first Business Operations hire, you’ll build the operational infrastructure... 
    Work at office
    Remote work

    Prelim

    San Francisco, CA
    7 days ago
  • $310k

     ...products. We partner across engineering, finance, legal, and operations to identify, negotiate, and execute strategic partnerships...  ...-efficiency. About the Role We’re hiring a Compute Business Operations Lead to drive high-priority, cross-functional initiatives that... 
    Work at office
    Local area
    Relocation package
    Flexible hours

    OpenAI

    San Francisco, CA
    more than 2 months ago
  • We’re seeking an experienced and highly analytical Finance & Business Operations leader to play a key strategic and operational role within our...  ..., operational, and corporate functions. You’ll own FP&A, lead core business operations, and manage critical partnerships across... 

    Pattern Biosciences

    Emeryville, CA
    14 hours ago
  • Position Overview The Sr. Manager of Business Operations for Amazon Music serves as the Music General Manager’s organizational backbone, owning...  ...range planning cycles, and goal‑setting mechanisms. The role leads the Program Management Office (PMO), a lean team that drives... 
    Work at office

    Amazon Music

    San Francisco, CA
    4 days ago
  • Nooks, based in San Francisco, is seeking a Business Operations professional to drive strategic initiatives as part of a rapidly growing AI company. The role involves working closely with executive leadership, managing business planning processes, and supporting data-driven... 

    nooks

    San Francisco, CA
    3 days ago
  • HireNow Staffing Inc. seeks a seasoned Business Operations Lead for an AI-native security platform. This role drives pricing strategy, financial reporting, and cross-functional execution across Finance, GTM, Product, and Leadership to scale operations during rapid growth... 

    HireNow Staffing Inc

    San Francisco, CA
    2 days ago
  • $215k - $260k

     ...with the Great Place to Work certification for the second year in a row. Position Overview The Business Sector Lead of Planning provides strategic, operational leadership and market growth across several service areas, including Agency Staffing, Community... 
    Work at office
    Local area
    Flexible hours

    BKF

    San Francisco, CA
    1 day ago
  • $60 per hour

     ...Mercor is hiring for the position of Google Workspace & Business Profile Owners. This remote role requires active management of a verified Google Business Profile, customer engagement to enhance online presence, and collaboration with industry representatives. Must have... 
    Hourly pay
    Contract work
    Remote work

    Mercor Inc

    San Francisco, CA
    2 days ago
  •  ...the Role We are seeking an experienced operations leader to oversee the day‑to‑day management...  ...before they impact operations. You will lead incident response efforts, drive...  ...improve operational processes to support business growth. Experience with high‑density GPU... 
    Work at office
    Remote work

    AI Fabrik

    San Francisco, CA
    3 days ago
  •  ...You can talk to both a technical engineer and a non-technical operator about the same problem. You care as much about whether something...  ...whether it shipped. What You’ll Bring 2-5+ years of experience in business operations, strategy, technical program management, or applied... 
    Flexible hours

    Jobr

    San Francisco, CA
    4 days ago
  •  ...Position Overview You'll own the day-to-day operations that keep Mach9 running: people, workplace, IT, internal systems, and the infrastructure...  ...team scale without losing rigor. Reporting to the Head of Business Operations and Finance, you'll be the operating partner who... 
    Work at office

    Quiet Capital

    San Francisco, CA
    1 day ago
  •  ...We're hiring an Operations Lead to bridge the gap between our technology and real-world logistics execution. You'll work directly with enterprise customers to deploy our platform, optimize their operations, and ensure they achieve measurable ROI. What you'll do Lead customer... 

    CIRCL

    San Francisco, CA
    2 days ago
  •  ...future where AI is embedded into how we operate, not layered on top. We're looking for a...  ...driving AI adoption and impact across Assort’s business teams. You'll partner closely with GTM,...  ...Sit one‑on‑one with each department lead to shape their quarterly AI goals and sequence... 
    Work at office

    assorthealth

    San Francisco, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Business Operations Lead. Be the first to apply!