Research Lab Technician I

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary The Morini and Slaugenhaupt Laboratories at the Center for Genomic Medicine, Massachusetts General Hospital (MGH), are seeking a highly motivated Research Technician to join an interdisciplinary team investigating the molecular mechanisms of Familial Dysautonomia (FD) and developing novel therapeutic strategies. The successful candidate will contribute to cutting-edge translational research, including single-cell transcriptomic studies of FD mouse models and the development and preclinical evaluation of innovative therapeutic approaches, including gene editing and small-molecule therapies aimed at correcting the underlying splicing defect responsible for the disease. The successful candidate will play a key role in advancing translational research on Familial Dysautonomia through both therapeutic development and disease modeling. Responsibilities will include supporting single-cell transcriptomic studies in FD mouse models, conducting preclinical efficacy studies of novel therapeutic approaches and performing molecular and cellular biology techniques such as genotyping, tissue processing, RNA isolation, qPCR, Western blotting, and next-generation sequencing library preparation. The candidate will also assist with mouse colony management, behavioral phenotyping, and the collection of high-quality samples for downstream genomic analyses. We are looking for a highly motivated, detail-oriented, and collaborative individual who thrives in a fast-paced research environment. The ideal candidate is organized, eager to learn, and comfortable working both independently and as part of a multidisciplinary team. A background or strong interest in neuroscience, genetics, genomics, molecular biology, or therapeutic development is highly desirable. Prior experience with mouse handling and colony management, as well as familiarity with RNA biology or next-generation sequencing techniques, is preferred but not required. Does this position require Patient Care? No Essential Functions Perform laboratory experiments following established protocols and procedures. Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines. Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed. Record experimental data accurately and maintain organized records of procedures, protocols, and results. Compile and analyze data using appropriate statistical and analytical methods. Assist in data interpretation and presentation, contributing to research findings and reports. Qualifications Education Bachelor's Degree Related Field of Study required Can this role accept experience in lieu of a degree? Yes Experience Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred Knowledge, Skills And Abilities Strong theoretical and practical knowledge of laboratory techniques and procedures. Familiarity with common laboratory equipment and instruments used in research experiments. Proficiency in data collection, analysis, and scientific software tools. Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively. Strong problem-solving skills and the ability to troubleshoot technical issues. Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges. Additional Job Details (if Applicable) Remote Type: Onsite Work Location: 185 Cambridge Street Scheduled Weekly Hours: 40 Employee Type: Regular Work Shift: Day (United States of America) Pay Range: $21.00 - $29.01/Hourly Grade: 5 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. EEO Statement 1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at View phone number on click.appcast.io. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. #J-18808-Ljbffr