Principal Scientist, Cutting-Edge In Vitro Platforms
Alnylam
A biotechnology firm in Cambridge, MA, is seeking a Principal Scientist to lead innovative advanced in vitro modeling for RNAi drug discovery. The role includes developing physiologically relevant model systems and collaborating across teams to evaluate siRNA delivery efficiency. The ideal candidate will hold a Ph.D. and have over 6 years of experience in biotechnology, with expertise in cellular and molecular biology and in vitro model development. Benefits include comprehensive health coverage and a generous 401(k) match. #J-18808-Ljbffr
- ...for a scientific leader to provide technical oversight in in vitro selection and cell-surface screening for viral and bacterial antigens... ...discovery capabilities and drive innovation within a dynamic team focused on advancing cutting-edge therapeutics. #J-18808-Ljbffr...Principal
- ...ODDITY is a consumer tech platform transforming the global beauty... ...impact. ODDITY Labs is our cutting-edge biotechnology R&D center,... ...ROLE We’re looking to hire a Principal Scientist in Bioengineering or... ...experience: Pre‑clinical in‑vitro testing within dermatology...PlatformPrincipalWork at officeShift work
$111.38k - $185.63k
...Principal Scientist, Oligonucleotide Analytical ChemistryAt GSK, we have... ...of the immune system with cutting-edge technology to transform people... ...accelerate GSK’s pipeline and platform technology ambitions. Key... ...development, including in vitro biology, bioanalysis, DMPK...PlatformPrincipalLocal area$106k - $176.6k
...patients' lives globally. By leveraging advanced science and cutting‑edge technologies, you will play a crucial role in transforming innovative... ...of obesity and cardiovascular diseases. As a member of the In Vitro Pharmacology team, you will be playing a significant role in...PrincipalPermanent employmentH1bLocal areaWorldwideVisa sponsorshipWork visaRelocation package$147.2k - $220.8k
...Overview We are seeking an accomplished and motivated Principal Scientist to lead innovation in advanced in vitro modeling to enable RNAi discovery and development.... ...to the strategic direction of discovery and platform development efforts. Collaborate cross-...PlatformPrincipalFull timeTemporary workFlexible hours$115.5k - $192.5k
...understanding of the immune system with cutting‑edge technology to transform people’s... ...infectious disease‑related initiatives. As a Principal Scientist, you will provide deep subject‑matter... ...bacterial, mammalian, and insect platforms) to support vaccine discovery and...PlatformPrincipalLocal area$166.77k - $202.09k
...experienced, creative, and highly collaborative scientist to join our Biotherapeutics... ...In this role, you will build and deploy cutting‑edge machine learning and structure‑based methods... ...in scaling an agentic antibody design platform from prototype to a core engine of...PlatformPrincipalFull timeTemporary work$144.8k - $227.9k
## Associate Principal Scientist, Biomarker Discovery, MultiomicsApplyremote type: Not Applicablelocations... ...in Cambridge, MA. Our team leverages cutting-edge Spatial Multiomics (CosMx WTx, Xenium... ...ATAC-seq, and spatial multiomics platforms such as CosMx, Xenium, COMET mIF, and...PlatformPrincipalFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$137.81k - $166.99k
## Principal Scientist, Analytical DevelopmentCambridge - MA - USFind out how well you match with this job**Working with Us** Challenging... ...with creativity, contributing to the development of a cutting-edge analytical platform.**Qualifications:*** Ph.D. in Analytical Chemistry,...PlatformPrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work- Director of Chemistry / Chemist Principal Scientist Cambridge, MA ODDITY is a consumer tech platform transforming the global beauty and wellness market. We deploy... ...in our growth and impact. ODDITY Labs is our cutting-edge biotechnology R&D center, powering product...PlatformPrincipalH1bWork at officeVisa sponsorshipShift work
$160k - $190k
...diseases using its proprietary RNA editing platform. Korro is generating a portfolio of... ...Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different... ...is seeking an experienced analytical scientist to join the growing CMC team. You will...PlatformPrincipalFull timeFlexible hours$144.8k - $227.9k
## Associate Principal Scientist, Biomarker Discovery Automation & Engineering, Multi-omicsApplyremote... ...collaborative group that leverages cutting-edge automation and advanced multiomics... ...Our team applies Spatial Multiomics platforms including CosMx WTx, Xenium, COMET...PlatformPrincipalFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$140k - $180k
...Our Cambridge, MA site is dedicated to cutting-edge research aligned with the company strategic... ...diseases. Design and execute in vitro and/or in vivo studies to validate therapeutic... ...with CNS delivery strategies and platform technologies is preferred. Expertise...PlatformPrincipalFull time$208k - $286k
...Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures,... ...and beyond. THE ROLE We are seeking a Principal Scientist (Embedded ML/Computational) to lead... ...pragmatic AI strategies, oversee method and platform development (e.g., systems design,...PlatformPrincipalFull timeInterim role- ...Pioneering Intelligence is seeking a Principal Scientist – Computational Protein Design to... ...harnessing the power of Flagship’s scientific platforms. Position Summary As Principal... .... Join us to shape the future of cutting-edge antibody therapeutics across Flagship...PlatformPrincipal
$99.6k - $223.4k
...Cloud Infrastructure (OCI) is building Oracle Video @ Edge (OVE), a next-generation video delivery platform optimized for live and linear streaming. This role... ...high-quality playback experiences. Why OCI Build cutting-edge streaming infrastructure leveraging UDP, MoQ,...PlatformPrincipalTemporary workFlexible hours- ...Associate Scientist / Scientist – xRNA Process Sciences Overview... ...purification to contribute to cutting-edge therapeutic programs. The... ...will support and execute in vitro transcription (IVT)... ...systems, particularly AKTA platforms. Knowledge and practical...Platform
- ...all-RNA-mediated gene writing platform via nonviral delivery to... ...collaborative and resourceful scientist/senior scientist with extensive... ...optimization of our CAR-T in vitro assays and will interface with... ...has a passion for working on cutting-edge technology, and can communicate...PlatformFull time
- Job title : Senior Scientist, Advanced Ocular In Vitro Models Location : Cambridge, MA About the Job Are... ...acquisition systems, and optimizing robotic platforms for multi‑step differentiation... ...of drug discovery, harnessing cutting‑edge AI, data, and digital platforms to...PlatformWorldwide
$137k - $215.27k
...innovative and dynamic AI/ML scientist with a passion for... ...computational methods with cutting‑edge experimental strategies to advance... ...with automated experimental platforms generating quality data at scale... ...utilizing large‑scale NGS, in‑vitro, in‑vivo and other...PlatformTemporary workLocal area- Scientist I - Discovery Research Immunology | Cambridge, MA We are... ...opportunity to contribute to cutting‑edge early drug discovery... ...conducting, and analyzing in‑vitro assays to address key biological... ...cytometry experiments using platforms and software such as FlowJo...PlatformContract work
$63 - $65 per hour
...Overview: Seeking a Contract Scientist to support the siRNA group within... ...the design and execution of cutting-edge experimental approaches to... ...functional team to advance siRNA platform development for therapeutic... .../Sr. Scientist for in vitro Pharmacology Waltham, MA $90,...PlatformContract workTemporary workPart time$67.6k - $80k
...Postdoctoral Fellow or Research Scientist with strong expertise in... ...organoids and related human in vitro systems. Lead the... ...high-throughput functional platforms, including: Single-unit extracellular... ...and integrate novel, cutting-edge technologies for functional...Platform- ...Overview We are seeking a highly motivated Principal Scientist to lead the development of scalable, cell-based assay platforms for evaluating and ranking multi‑epitope mRNA... ...cross‑functional teams Nice‑to‑Have (Edge) Qualifications Experience in vaccine development...PlatformPrincipal
- ...United Cerebral Palsy of Georgia is looking for a Principal Scientist in Cambridge, MA, to lead cutting-edge machine learning research focused on Alzheimer's, Parkinson's, and other neurodegenerative diseases. You will analyze large-scale omics data to uncover disease...Principal
$108.5k - $201.5k
...Position Summary The Principal Scientist, ADPKD Biology Lead is a senior, lab-embedded scientific... ...human‑relevant model systems, including 3D platforms, and deliver decision‑grade biology... ...on understanding of state‑of‑the‑art in vitro methods, including molecular biology, biochemistry...PlatformPrincipal$108.5k - $201.5k
# Principal Scientist I/II, Molecular PathologyREQ-10079427Jun 03, 2026USA### Summary Cambridge, MA... ...**proteomics strategy and technology platforms** in a translational research environment... ...-making*** Experience with: + In vitro and in vivo models + Clinical or post-mortem...PlatformPrincipal$142.5k - $256.5k
...technical leadership for in vitro selection and cell-surface screening... ...cell–based screening platforms that interrogate broadly applicable... ...This role is intended for a scientist ready to own and evolve a... ...ownership consistent with a Principal Scientist role.**Here’s What...PlatformPrincipalWork at officeWork from home- Senior Scientist / Skin Tissue Engineering Cambridge, MA WHO WE ARE ODDITY is a consumer tech platform transforming the global beauty and wellness... ...impact. ODDITY Labs is our cutting-edge biotechnology R&D center,... ...protocols for in vitro primary cell culture under...PlatformWork at officeShift work
- ...Job Title Principal Scientist, Neurology Research, Cambridge MA Location Cambridge, MA About the Job As a... ...Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science. Equal Employment...PlatformPrincipalShift work
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