Lead Local Operations Manager - Solid Tumor Oncology (1 of 2 Openings)

Role Overview Lead Local Operations Manager – Solid Tumor Oncology. The Lead LOM is a senior operational leader accountable for US country level site performance, operational strategy, and delivery across the end‑to‑end clinical trial lifecycle. The Lead LOM serves as the US operational nexus for assigned trials, coordinating Local Operations Managers, resolving complex escalations, and integrating country level operational insights into global trial planning and execution. Responsibilities Own US site level operational delivery for assigned sites. Lead and coordinate local trial team activities in compliance with SOPs, procedural documents, and regulations. Lead local project planning activities to meet recruitment targets and deliver high quality data on time and within study budget, including development of local trial specific procedures and tools, recruitment planning, contingency and risk management, and budget forecasting. Provide leadership oversight and mentoring support to other local operations managers assigned to the trial or program. Shape US trial operational strategy and integrate site insights into global feasibility and startup planning. Serve as the primary US operational interface to global trial leadership. Monitor country level operational KPIs and identify systemic risks and mitigation strategies. Act as escalation point for complex site contracting, operational, and recruitment issues. Represent US local operations at investigator and/or study coordinator site meetings and key governance forums. Act as subject matter expert for assigned protocols and develop strong therapeutic knowledge to support roles and responsibilities. Represent Oncology Site Enablement on cross‑functional teams and elevate US site insights to inform global decision‑making and continuous improvement. Travel up to 10% of the time. Qualifications Minimum bachelor’s degree in Life Sciences, Nursing, Pharmacy, or related scientific discipline (or equivalent experience); advanced scientific or clinical degrees an advantage. At least 4 years of experience in clinical trial operations, trial management, site management, or clinical monitoring, including significant experience in complex, high‑priority, or multi‑site trials, especially oncology. In‑depth understanding of the clinical development process and end‑to‑end trial delivery, with demonstrated expertise in feasibility, startup strategy, enrollment execution, quality oversight, and closeout. Strong and applied knowledge of GCP, regulatory requirements, inspection readiness, and compliance management, with experience supporting audits and regulatory inspections. Demonstrated leadership experience, including coaching, mentoring, and guiding other Local Operations Managers or site‑facing roles in a player‑coach capacity. Proven ability to lead through influence, resolve escalations, and drive alignment across cross‑functional and global trial teams. Experience shaping or contributing to country‑level or trial‑level operational strategy, including site selection, enrollment forecasting, and risk mitigation planning. Strong analytical skills with the ability to interpret country‑ and site‑level KPIs, identify systemic risks, and implement corrective actions. Excellent written and verbal communication skills in both the local country language (English) and in English for global forums. Willingness to travel up to 10% as required, including overnight stays and participation in investigator meetings and key trial governance meetings. Demonstrated flexibility, resilience, and ability to operate effectively in a highly complex, fast‑changing clinical development environment. Compensation The anticipated base pay range for this position in the US is $109,000–$174,800. For the BayArea, the range is $125,000–$201,250. The position is eligible for an annual performance bonus in accordance with company guidelines. Benefits Medical, dental, vision, life insurance, short‑ and long‑term disability, business accident insurance and group legal insurance. Participation in the consolidated retirement plan (pension) and 401(k). Vacation– 120hours per calendar year; Sick time– 40hours per calendar year (48hours in Colorado, 56hours in Washington). Holiday pay– 13days per calendar year. Work, Personal and Family Time– up to 40hours per calendar year. Parental Leave– 480hours within one year of birth/adoption/foster care of a child. Bereavement Leave– 240hours for an immediate family member, 40hours for an extended family member per year. Caregiver Leave– 80hours in a 52‑week rolling period. Volunteer Leave– 32hours per calendar year. Military Spouse Time‑Off– 80hours per calendar year. Equal Opportunity Employer Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected under federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. This job posting is anticipated to close on May20,2026. #J-18808-Ljbffr 6084-Janssen Research & Development, LLC Legal Entity