Senior Scientist - Discovery Immunology, Autoimmunity

Job Description Senior Scientist, Discovery Immunology - Autoimmunity Our company, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. We are seeking a Growth and Improvement minded Senior Scientist Immunology to join our Immunology Discovery therapeutic area at our organization in Cambridge MA and can help drive our Strategic Operating Priorities. Invent | Pursue the Most Promising Internal and External Science to Address Significant Unmet Medical Needs Adapt | Develop Our People, Culture and Business Model to Evolve with a Dynamic Landscape Diverse Talent | We are committed to providing an inclusive and welcoming environment with supporting leadership behaviors because having a high-performing, engaged workforce is critical to our ability to deliver innovative solutions to patients and customers around the world Values and Standards | Our Steadfast Commitment to Our Values and Standards will Continue to Guide Us as We Take on New Challenges and Will Always be Fundamental to Our Success – They are a Competitive Advantage for Us Key Responsibilities Work in a team that supports early development of novel therapeutics for autoimmune and inflammatory disease indications Validating novel immunology targets to advance drug discovery programs to clinical candidates Education The ideal candidate will have a PhD degree in Biological Sciences, Immunology, Pathology, Biochemistry, Biotechnology, Biomedical Engineering, Genetics/Genomics, or related STEM field with experience in the area of Immunology. Experience in the pharmaceutical / biotech industry is preferred. Required Expertise with multi-parameter flow cytometry, developing in vitro assays to investigate immune function and possess a deep knowledge of technologies commonly used to assess immune endpoints. Experience in primary immune cell isolation and stimulation, proliferation and apoptosis assays, immunoassay techniques/platforms (e.g. Western, ELISA, Mesoscale), as well as RT-PCR. Candidate should be competent in standard scientific software used for data analysis (e.g. Microsoft Excel) as well as Microsoft Word and PowerPoint and Graphpad Prism. Good data handling and recording skills as well as the ability to interpret moderately complex data sets and draw appropriate conclusions from them. Excellent organization and ability multi-task and manage multiple projects Ability to adapt to rapid changes in projects priorities, define and meet aggressive timelines Committed to working in a collaborative manner across functional areas within a matrixed organization Excellent oral and written communication skills. Curious, self-motivated with principled verbal and written communications Preferred Expertise in key areas of autoimmunity focused around modulation of immune response and induction of tolerance Experience with preclinical model systems and human disease tissues and transcriptomic analyses Experience leading biologics or chemistry discovery projects Background in clinical immunology, translational biomarkers Ability to analyze multi-OMICs datasets #EligibleforERP Required Skills: Adaptability, Assay Development, Autoimmune Diseases, Biochemical Assays, Cell Culture Techniques, Detail-Oriented, Drug Target Identification, Flow Cytometry, Immunoassays, Immunology, Molecular Biology, Personal Initiative, Teamwork, Transcriptomics Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts The salary range for this role is $119,100.00 - $187,500.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: No Travel Requirements: No Travel Required Flexible Work Arrangements: Not Applicable Shift: Not Indicated Valid Driving License: No Hazardous Material(s): Biological samples and standard lab reagents Job Posting End Date: 06/11/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.