Research Scientist, Lentiviral Vector Purification and Analytics

Summary The Lentiviral Vector (LVV) Team in the Biologics Research Center (BRC) at Novartis, Cambridge, MA is seeking a highly motivated Research Scientist with experience in production and purification of viral vectors to join our team. In this role, you will play a key part in advancing our Cell and Gene Therapy research initiatives and contributing to groundbreaking research in CAR-T cell therapy. About The Role Internal Job Title: Research Scientist I/II Position Location: Cambridge, MA, onsite This role is based in Cambridge, MA. Novartis is unable to offer relocation support for this role; please only apply if this location is accessible for you. Join a collaborative team at the forefront of cell and gene therapy research. As a Research Scientist focused on lentiviral vector purification and analytics, you will apply hands‑on laboratory expertise to help develop, optimise, and characterise viral vector processes that support next‑generation CAR‑T programmes. Key Responsibilities Lab‑based position requiring hands‑on execution of lentiviral vector purification activities including clarification, chromatography, and TFF. Execute analytical methods (molecular‑ and cell‑based) to assess quality of the purified vector. Write and review protocols, technical reports, technology transfer documents, SOPs, instrument procedures, and other lab documents. Plan and prioritise work to meet goals while managing multiple research activities. Support experimental design, data analysis, and troubleshooting. Identify root causes, implement solutions, and verify effectiveness. Present scientific data and contribute openly to discussions. Document experimental procedures and processes thoroughly. Collaborate across teams, share knowledge, and train team members in technical areas as needed. Essential Requirements BS or MS in bioengineering, virology, or related field, with relevant lab experience (not a PhD‑level position). 1–3 years of experience in protein and/or viral vector purification. Hands‑on experience with chromatography and filtration techniques, including TFF and depth filtration. Strong coordination, communication, collaboration, learning agility, and self‑motivation. Proficiency with Word, Excel, PowerPoint, and GraphPad Prism. Excellent oral, written, and interpersonal communication skills. Desirable Requirements BSL2 experience with AAV, lentiviral, or retroviral vector production. Proficiency in aseptic technique, cell culture, molecular biology, and analytical testing. Bioreactor experience. Compensation and Benefits Salary ranges: Research Scientist I: $66,800–$124,000 per year; Research Scientist II: $81,200–$150,800 per year. Final salary determined based on relevant skills and experience and reviewed periodically. Compensation includes a performance‑based cash incentive and, depending on the level, eligibility for annual equity awards. US‑based eligible employees receive a comprehensive benefits package including health, life and disability benefits, a 401(k) with company contribution and match, and various other benefits. Employees are eligible for a generous time‑off package including vacation, personal days, holidays and other leaves. EEO Statement The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility & Reasonable Accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please contact or call View phone number on click.appcast.io. Include the job requisition number in your message. #J-18808-Ljbffr