Bioprocess Applications Engineer 3

Work Location: Bedford, MassachusettsShift: Department: LS-PS-RUAP PAT & Digital ApplicationsRecruiter: Michelle ColeThis information is for internals only. Please do not share outside of the organization.Your RoleWe’re seeking a Bioprocess Applications Engineer 3 to join the Single Use and Integrated Systems PAT & Digital Applications team, part of MilliporeSigma’s Process Solutions business unit. Based at our Bedford, MA campus, this role will support the development and application of integrated platform solutions for next-generation bioprocessing.In this role, you will combine engineering fundamentals, hands-on experimentation, data analysis, modeling, and customer-focused problem-solving to evaluate emerging technologies and characterize system performance. You will translate application insights into product requirements, technical recommendations, and practical guidance that support both product development and customer success. Key responsibilities include:Integrate PAT sensors and inline spectroscopy into downstream unit operations, including Protein A chromatography, UF/DF, and other mAb purification stepsLead development, optimization, and lifecycle management of Raman chemometric models for mAb streams, buffers, and excipientsOversee qualification, deployment, and lifecycle support of Raman instruments and inline sensing units, including model transfer and qualification activitiesIdentify and address customer PAT performance gaps, competitive technology landscapes, and process design targets through data-driven solutions and strategic recommendationsDrive technical strategy in inline spectroscopy, advanced process control, and digitalization of process and analytical toolsLead cross-functional contributions spanning R&D, Manufacturing, Quality, Sales, and Product Management to commercialize PAT and digital solutionsProduce customer-facing technical content, including application notes, technical guides, and webinarsSupport customer trials and investigations; capture actionable feedback to inform product and application developmentWho You AreMinimum Qualifications:Ph.D. in Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering disciplineORMaster’s degree in Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline AND 4+ years of industry experienceORBachelor's degree in a Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline AND 5+ years of industry experiencePreferred Qualifications:Experience in biopharmaceutical process development, PAT implementation, or analytical method development in a biomanufacturing context, with a demonstrated track record of leading technical projects to completionTechnical expertise and hands-on experience with PAT sensors, inline spectroscopy (e.g., Raman), chemometric model development, process automation, and downstream biomanufacturing unit operationsExperience leading projects of moderate to extended complexity, driving results and meeting milestones with excellent problem-solving skills, a collaborative mindset, and strong adherence to data integrity and cGMP documentation standardsAbility to communicate effectively with peers, customers, vendors, and stakeholders through written technical reports, oral presentations, timely discussions and experience mentoring junior engineers Ability to apply engineering and scientific principles to resolve technical challenges of extended scope and complexity, with the ability to translate analytical insights into actionable process improvements and strategic recommendationsPay Range for this position: $84,900 - $127,300 annuallyThe offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.