Senior Scientist, Translational Science & Biomarkers

Job Description

Job Description

Location : Redwood City, CA  

Company Overview:  

ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response.    

At ImmunEdge, we are driven by a shared commitment to improving human health through innovative science. We are building a culture based on kindness, collaboration, and a deep passion for advancing science. As an early joiner to the company, you will help cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork. Whether you’re working in the lab, the office, or across functional teams, you will find an inclusive space where your contributions matter and your professional growth is supported.  Join us in shaping the future of biotechnology. Together, we can change lives.   
Position Summary
The position is on the Translational Science & Biomarkers team which supports preclinical and clinical programs through the discovery, development, and validation of biomarkers that inform mechanism of action, indication selection, patient stratification, and clinical development strategy. ImmunEdge is seeking a highly collaborative and scientifically rigorous translational scientist with strong expertise in immune-oncology and tumor biology. The successful candidate will integrate molecular, cellular, and tissue-based data to characterize therapeutic targets, define tumor and immune biology, identify potential biomarkers, and support precision medicine strategies across ImmunEdge's pipeline. The ideal candidate will have hands-on experience with biomarker assays, tumor specimens and clinical samples.

Key Responsibilities

• Conduct and interpret molecular, cellular, immunological, blood-based, and tissue-based assays using mouse- and human-derived samples across preclinical and clinical research
• Conduct multiparameter flow cytometry, immune-cell phenotyping, functional cellular assays, and assessment of blood-based soluble biomarkers.
• Analyze and integrate complex datasets, including genomic/transcriptomic data, multiparameter flow cytometry, tissue-based biomarkers, and experimental data, to characterize tumor and immune biology and identify clinically relevant biomarkers.
• Lead and drive major components of the translational and biomarker strategy by proposing and testing new hypotheses that support therapeutic development, indication prioritization, and patient-selection strategies.
• Execute clinical biomarker strategies to support patient stratification, pharmacodynamic assessment, mechanism-of-action evaluation, and clinical development, including biomarker assay implementation, clinical sample analysis, and integration of tissue, genomic, and translational data. 

Requirements

• Ph.D. in Immunology, Cancer Biology, Molecular and Cellular Biology, or a related field (or M.S. with additional relevant experience).
• 5-8 years of industry experience in oncology drug development, translational science, biomarker development, or a related area.
• Strong knowledge of oncology and immuno-oncology, including tumor–immune interactions and mechanisms of therapeutic response and resistance.
• Proficiency with laboratory techniques including tissue culture, ELISA, qPCR, western blotting, flow cytometry, and tissue-based assays.
• Experience working with tumor specimens and clinical samples is strongly preferred. 
• Experience integrating genomic/transcriptomic data, IHC/pathology, clinical metadata, and other multimodal biomarker datasets.
• Highly collaborative, intellectually curious, strategically minded, and able to work effectively across disciplines.

Expected Salary Range : $137,940 - $206,910

We encourage candidates of all levels to apply as there is sometimes flexibility on job level and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity, and location.

ImmunEdge offers a competitive employment package that includes an annual bonus plan, equity, and a generous benefits package including comprehensive health (medical, dental, and vision) insurance for our employees and their families, a 401k plan, FSA plans (medical, dependent), an Employee Assistance Plan, and a holiday and paid time off plan. 

At ImmunEdge, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. ImmunEdge will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws. 

Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation. 

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