Senior Medical Director
Enigma Search
Senior Medical Director
South San Francisco, California, United States
Medical Director / Senior Medical Director (Neurology & Early Development)
Location: South San Francisco, CA (Onsite)
Category: Clinical Sciences / R&D
Our client is seeking a Medical Director or Senior Medical Director to lead their Neurological and Neuropsychiatric clinical portfolio.
This is a high-impact role reporting directly to the Head of Clinical Sciences. You will be the clinical architect for programs moving from preclinical discovery into human "Proof-of-Mechanism" and "Proof-of-Concept" trials.
The Impact You Will Make
- Strategic Leadership: Lead high-performing cross-functional teams to translate preclinical data into robust human clinical strategies and biomarker development.
- Experimental Medicine: Design and execute innovative "Phase 0" through Phase 2 studies to demonstrate proof-of-mechanism for novel targets in the neuropsychiatric space.
- Collaborative Discovery: Act as a key interface between research and drug development, working closely with discovery scientists and external partners to shape disease indication strategies.
- Clinical Expertise: Utilize your medical background to guide the development of preclinical models and ensure they align with human clinical needs.
- Regulatory & Scientific Content: Author and provide expert medical oversight for protocols, Investigator Brochures (IBs), Clinical Study Reports (CSRs), and regulatory submissions.
Who You Are
- Physician-Scientist: You hold an M.D. or an M.D./Ph.D. with a deep scientific mindset.
- Neurology Expert: Board certification or eligibility in Neurology or Pediatric Neurology is highly preferred.
- Proven Industry Veteran: You have 5+ years of translational or clinical drug development experience within biotech, pharma, or a top-tier academic research setting.
- Early Phase Specialist: You possess direct experience or a deep working knowledge of early clinical trial methodology (Phase 0, 1, and 2).
- Collaborative Leader: You excel in a matrixed environment, possessing the ability to lead through influence and bring out the best in cross-functional teams.
Why This Role?
This is not a traditional "late-stage" medical monitoring role. This is a position for a scientist-clinician who wants to be at the forefront of Early Development (Translational), working on novel targets that have the potential to redefine how we treat neurological diseases.
Or refer someone
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Medical Director in South San Francisco, CA vacancy
$374k
...drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.Position Description:The Medical Director/Senior Medical Director at Calico will report to the Head of Clinical Sciences and will be responsible for...Senior$198.6k
...they need today and for generations to come. Creating a world where we all have more time with the people we love. The Sr. Medical Science Director/Sr. Medical Director at Genentech puts patients and science at the center of all actions. They drive medical tactics aimed...SeniorFull timeLocal areaShift work$324k - $409k
...science innovation in both the US and China and capitalizing on the strengths of each geographic location.Position Summary:The Senior Medical Director will provide medical support on clinical drug development of the assigned compound(s), including being a key driver of...SeniorContract work$330k - $390k
A precision medicine company is seeking a Senior Medical Director to lead clinical programs for dry AMD therapeutics. This role involves designing and executing clinical development plans, managing clinical trials, and ensuring the highest standards of quality and impact...SeniorRemote job- Denali Therapeutics Inc. is seeking an Executive Medical Director to lead program strategy and clinical development for TV-mediated therapeutics targeting neurodegenerative diseases. This role requires deep expertise in trial design, regulatory strategy, and cross-functional...Senior
$214.5k - $398.3k
...world where we all have more time with the people we love. US Medical, part of Genentech, is passionate about delivering on Our Promise... ...omnichannel customer experience that maximizes medical impact. Senior Matrix Leadership & Influence: Drive the cultural and...SeniorFull timeWork at officeLocal areaShift work3 days per week- IDEAYA Biosciences in South San Francisco seeks a Medical Director of Patient Safety and Pharmacovigilance to lead medical review of International Case Safety Reports (ICSRs) across the company’s global pharmacovigilance program. This role provides medical leadership and...Senior
- ...and guide regulatory responses with cross-functional colleagues. You will collaborate with pharmacology, toxicology, regulatory, and medical affairs to optimize dose selection, safety monitoring, and labeling considerations while supporting NDA/sNDA submissions and risk...Senior
- Scientific Director / Senior Medical Director, Medical Affairs - Global Oncology Pipeline (Prostate Cancer) We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times...Senior
$299k - $349k
A global biopharmaceutical company in California is seeking a Senior Medical Director to lead late-stage clinical development programs in Oncology. This role requires an MD with board certification in Oncology and at least 5 years of clinical development experience, emphasizing...Senior- AbbVie is seeking a Product Safety Team (PST) lead for late-stage oncology products to set safety strategy across the lifecycle, including surveillance, signal detection and risk management. The role interfaces with PK/toxicology leads, regulatory and clinical development...Senior
$337.5k - $412.5k
...professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Medical Director to join our Clinical Sciences team and take a central role in pioneering the future of healthcare. As a Senior Medical...Senior3 days per weekMaze Therapeutics
South San Francisco, CA21 days ago- AbbVie is seeking an Executive Medical Director for Oncology Early Development to lead the design, execution, and interpretation of clinical trials across development programs. This role requires deep medical expertise, regulatory know-how, and cross-functional leadership...Senior
- ...AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including...Senior
- Zai Lab in South San Francisco is seeking a Senior Medical Director to lead late-stage oncology development programs, including pivotal Phase III trials and regulatory submissions. You will serve as Medical Monitor, provide scientific leadership, and collaborate with regulatory...SeniorWork at office
$337.5k - $412.5k
Maze Therapeutics in South San Francisco is looking for a Senior Medical Director to lead clinical development programs focused on innovative treatments. This role requires 6+ years of drug development experience and expertise in clinical trial design. The Senior Medical...Senior$325k - $358k
...Responsibilities Broadly represent the interests of Alumis as a senior leader and spokesperson for Clinical Development within the... ...contribute to cross-functional teams within Research, Biomarkers, Medical Affairs, Commercial, and Study Team as an expert within the...SeniorRemote work- AbbVie is seeking a senior clinical development expert to oversee direction, planning, execution, and interpretation of clinical trials... ...to translational strategies in partnership with Discovery and Medical Affairs. The role requires MD/DO with 2+ years of clinical...Senior
$270k - $360k
Medical Director/Senior Medical Director, Clinical Development TenvieTherapeutics is developing precision‑engineered small molecule therapies to address core drivers of neurological and peripheral diseases: neuroinflammation and cellular dysfunction. Leveraging its proprietary...SeniorLocal areaRemote work$299k - $349k
...commercializing best-in-class and first-in-class therapies that address medical conditions with significant unmet needs in oncology,... ..., global reach, and long-term growth. Job Description The Senior Medical Director will lead late-stage clinical development programs in...SeniorWork at officeWorldwideRelocation package- ...solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable... ..., X and YouTube. Job Description Purpose: The Senior Medical Director leads the direction, planning, execution, and interpretation...SeniorLocal area
AbbVie Inc.
South San Francisco, CAa month ago $182k - $346k
Senior Medical Director, Hematology Clinical Development Full-time Salary Min: 182000 Salary Max: 346000 Workday Global Grade: 22 Compensation: USD 182,000 - USD 346,000 - yearly About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions...SeniorFull timeLocal area$330k - $390k
Senior Medical Director / Executive Medical Director / Vice President Character Biosciences | Posted Mar 14 Full-time Brisbane Unknown About Character Biosciences Character Biosciences is a precision medicine company pioneering targeted therapies for ophthalmology....SeniorFull timeRemote work$300k - $400k
...indications to maximize the therapeutic potential of our portfolio. Position Summary Alumis is seeking an experienced Executive Medical Director or Senior Medical Director to lead clinical development strategy and execution for Phase 1 and Phase 2 studies in neurology and...SeniorRemote work$242k - $347k
...discoveries. These values are the foundation of our work, empowering us to make a real difference, every day. Position Title Senior Director / Medical Director - Clinical Trial Lead Department Clinical Development Reports To Vice President, Clinical Development Lead...Senior3 days per week- AbbVie is seeking a senior Clinical Pharmacology leader to conceive, execute, and manage multi-disciplinary pharmacology development plans that meet commercial and regulatory goals. The role leads PK/PD strategy, proposes study plans, and collaborates with internal teams...Senior
- The Center for Autism and Related Disorders, LLC (CARD) seeks a Clinical Supervisor II to oversee clinical treatment across CARD centers, patients’ homes, schools, and telehealth. This role involves developing treatment plans, supervising technicians, and coordinating care...SeniorRemote jobRelocation package
$280.4k - $316.5k
...Senior Director, Translational Medicine and Clinical Biomarkers Own the translational science that decides which patients get treated and how — leading biomarker strategy across Nurix’s entire oncology and immunology portfolio. This is a senior, portfolio-level role...SeniorFull timeLocal area$166k - $209k
...geographic location.Position Summary:The Senior Manager, Clinical Business Systems is responsible... ...applications. Reporting to the Associate Director, GxP Operations, this role is the primary... ...the pharmaceutical, biotechnology, or medical device industries.Hands-on experience...SeniorContract workWork at officeRemote work- ...Job Description Job Description Job Title: Senior Medical Director, Medical Affairs Position Type: Full Time Location: Thousand Oaks, CA or San Francisco Bay Area Company Description: Latigo Biotherapeutics, Inc. is a biotechnology company focused...SeniorFull time
Latigo Bio
San Francisco, CA6 days ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Medical Director. Be the first to apply!
Related searches
- health insurance manager South San Francisco, CA
- director population health South San Francisco, CA
- health services director South San Francisco, CA
- senior director clinical development South San Francisco, CA
- hospital manager South San Francisco, CA
- medical operations supervisor South San Francisco, CA
- director environmental health & safety South San Francisco, CA
- medical and health service manager South San Francisco, CA
- healthcare data manager South San Francisco, CA
- occupational health manager South San Francisco, CA