Postdoctoral Fellow - Thoracic Head & Neck Medical Oncology (F. Skoulidis' Lab)

Overview Postdoctoral Fellow - Thoracic Head & Neck Medical Oncology (F. Skoulidis' Lab) at MD Anderson Cancer Center. Positions available to study molecular mechanisms of therapeutic response and resistance to RAS inhibition in non-small cell lung cancer (NSCLC) in the laboratory of Ferdinandos Skoulidis, MD, PhD, at the University of Texas MD Anderson Cancer Center in Houston, TX. The lab focuses on the molecular diversity of KRAS-mutant NSCLC and developing rational, tailored treatment strategies for patients with KRAS-mutant lung tumors. Responsibilities Trainees will perform basic and translational research involving molecular biology approaches (CRISPR/Cas technology, Western blotting, ELISA, immunohistochemistry), in vitro assays (drug screening, flow cytometry, development of resistant cell lines) and in vivo experiments using xenograft, syngeneic, and genetically engineered mouse models of KRAS-mutant lung cancer. Candidates with prior experience in computational biology will analyze single-cell RNA sequencing, whole-exome sequencing, and in situ transcriptomics data. Trainees will present findings at regular lab meetings, departmental seminars, and national conferences, and submit findings for publication in peer-reviewed journals. Qualifications PhD and/or MD. Ideal candidate has less than 2 years of prior postdoctoral experience and a background in cancer or cell and molecular biology. Experience in RAS signaling and targeting, and studies involving mouse models of KRAS-driven cancers, is preferred. Computational biology/bioinformatics experience (including analysis of single-cell RNA sequencing data and in situ transcriptomics) is desirable. Applicants should be innovative, highly motivated to pursue an independent career in biomedical research, and have excellent written and spoken English. Additional Information Applications are invited from qualified individuals interested in working in a translational research lab, with three professional references. Lab profile: Position Information MD Anderson offers full-time postdoc positions with a salary range of $64,000 to $76,000, depending on years of postgraduate experience. Benefits include medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and recognition programs. Offsite work arrangements are subject to approval and may be modified based on business needs. Equal Employment Opportunity: The University of Texas MD Anderson Cancer Center provides equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by law. #J-18808-Ljbffr MD Anderson Cancer Center