Research Associate I (Per Diem) - Gibb Lab - Pathology

Cedars-Sinai is committed to pushing the frontiers of medicine and discovering new technologies and innovations that will change how we diagnose and treat disease. As an international leader in biomedical research, we translate discoveries into successful treatments with global impact. With your help, we can change the future of healthcare! Are you ready to be a part of breakthrough research? The Gibb Laboratory investigates inflammatory mechanisms in patients with sickle cell disease (SCD) and lupus, focusing on mechanisms regulating immune responses to red blood cell (RBC) antigens (i.e., KEL antigens) following RBC transfusion. The goal of these studies is to understand why patients with SCD and autoimmunity have the highest incidence of these detrimental anti-RBC antibody responses, which cause potentially fatal hemolytic transfusion reactions and severely limit access to compatible blood for these populations. Specifically, the lab has uncovered a critical role for antiviral cytokines (type I interferons, IFNα/β) and IFNα/β-stimulated genes (ISGs) in these antibody responses. Disrupting this pathway prior to RBC transfusion may promote transfusion safety by preventing hemolytic transfusion reactions. Learn more at Gibb Lab at Cedars-Sinai. Working under direct supervision, the Research Associate I will perform a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research. Assists in general laboratory activities, including maintenance of reagents and stocking of supplies. Files and monitors documents. The RA I will be able to perform routine cellular, micro-and molecular biology procedures including, but not limited to Western, Northern blot, DNA/RNA, PCR, protein extraction, cell culture, Immunohistochemistry, and staining. This position does not have supervisory responsibilities. Primary Job Duties and Responsibilities:

• Keeps accurate and detailed project records of experiments and results.
• May assist with animal husbandry.
• Maintains lab equipment and related records.
• Transports, processes and logs samples.
• Maintains computer database with relevant clinical information.
• Performs lab maintenance duties, including glassware cleaning and

sterilization. * Maintains stocks of general lab materials, and places orders for lab equipment and supplies in a timely manner.

• Assists new students and fellows at the laboratory.
• Assists in the operation of specialized equipment and machinery.
• Observes and complies with safety standards and procedures.

Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. Cedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.